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Application of Image Processing and Finite Element Analysis in Bionic Scaffolds’ Design Optimizing and Fabrication

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Life System Modeling and Simulation (LSMS 2007)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 4689))

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Abstract

Design optimizing is the key step in obtaining bionic scaffolds with proper shape and inner microstructure, which are two critical parameters for bionic scaffolds in Tissue Engineering. In this paper, the application of image processing and finite element analysis in the design optimizing of bionic scaffold’s shape and inner microstructure were studied respectively. The bionic scaffold’s shape was obtained through Mimics’ image processing and 3D reconstruction technologies. Finite element analysis (FEA) was used in evaluating the mechanical properties of scaffold’s structure models with different macro-pores shape and distribution to obtain the optimized parameters. Three groups of bioceramic scaffolds samples were fabricated through an indirect method combining stereolithography (SLA) and slurry casting, and then mechanical experiments were tested. The change trendy of the compressive strength obtained through mechanical experiments was consistent with the FEA results basically so the significance of FEA in bionic scaffolds’ design optimizing was proved.

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References

  1. Tan, K.H., Chua, C.K., Leong, K.F., Cheah, C.M.: Scaffold development using selective laser sintering polyetheretherketone-hydroxyapatite biocomposite blends. Biomaterials 26, 4281–4289 (2005)

    Article  Google Scholar 

  2. Yang, S.F., Leong, K.F., Du, Z.H., Chua, C.K.: The design of scaffolds for use in tissue engineering: Part 1-Traditional factors. Tissue Eng. 7(6), 679–690 (2001)

    Article  Google Scholar 

  3. Linbo, W., Jiandong, D.: Compression Molding of PCL Porous Scaffolds with complicated shape for Tissue Engineering. Polymer Material Science and Engineering 25(1), 296–299 (2005)

    Google Scholar 

  4. Deville, S., Saiz, E., Tomsia, A.P.: Freeze casting of hydroxyapatite scaffolds for bone tissue engineering. Biomaterials 27, 5480–5489 (2006)

    Article  Google Scholar 

  5. Madihally, S.V., Howard, W.T.: Matthew Porous chitosan scaffolds for tissue engineering. Biomaterials 20, 1133–1142 (1999)

    Article  Google Scholar 

  6. Junmin, Q., Kai, C., Hao, A., Zhihao, J.: Progress in research of preparation technologies of porous ceramics. Ordnance Material Science and Engineering 28(5), 60–64 (2005)

    Google Scholar 

  7. Woesz, A., Rumpler, M., Stampfl, J., Varga, F.: Towards bone replacement materials from calcium phosphates via rapid prototyping and ceramic gelcasting. Materials Science and Engineering C 25, 181–186 (2005)

    Google Scholar 

  8. Chen, Z., Li, D., Lu, B.: Fabrication of osteo-structure analogous scaffolds via fused deposition modeling. Scripta Materialia 52, 157–161 (2005)

    Article  Google Scholar 

  9. Williams, J.M., Adewunmi, A., Schek, R.M., Flanagan, C.L.: Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. Biomaterials 26, 4817–4827 (2005)

    Article  Google Scholar 

  10. Chen, V.J., Smith, L.A., Ma, P.X.: Bone regeneration on computer-designed nano-fibrous scaffolds. Biomaterials 27, 3973–3979 (2006)

    Article  Google Scholar 

  11. Kalitaa, S.J., Bosea, S., Hosickb, H.L.: Amit Bandyopadhyay, Development of controlled porosity polymer-ceramic composite scaffolds via fused deposition modeling. Materials Science and Engineering C 23, 611–620 (2003)

    Google Scholar 

  12. Zein, I., Hutmacher, D.W., Tan, K.C.: Fused deposition modeling of novel scaffold architectures for tissue engineering applications. Biomaterials 23, 1169–1185 (2002)

    Article  Google Scholar 

  13. Leea, M., Dunna, J.C.Y., Wu, B.M.: Scaffold fabrication by indirect three-dimensional printing. Biomaterials 26, 4281–4289 (2005)

    Article  Google Scholar 

  14. Leukers, B., Gulkan, H., Irsen, S.H.: Hydroxyapatite scaffolds for bone tissue engineering made by 3D printing. Journal of Materials Science: Materials in Medicine 16, 1121–1124 (2005)

    Article  Google Scholar 

  15. Huanwen, D., Yingjun, W., Qingshui, Y.: Recent development of Computer-aided tissue Engineering. Chinese Journal of Reparative and Reconstruction of Surgery 5, 574–577 (2006)

    Google Scholar 

  16. Xi, H., Longbiao, Z., Zhisong, Z., Jianwei, Z.: CT-image Based Reverse of Custom Made Stem. Journal of Nantong University (Natural Science) 5, 52–56 (2006)

    Google Scholar 

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Kang Li Xin Li George William Irwin Gusen He

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© 2007 Springer-Verlag Berlin Heidelberg

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Lin, L., Zhang, H., Yao, Y., Tong, A., Hu, Q., Fang, M. (2007). Application of Image Processing and Finite Element Analysis in Bionic Scaffolds’ Design Optimizing and Fabrication. In: Li, K., Li, X., Irwin, G.W., He, G. (eds) Life System Modeling and Simulation. LSMS 2007. Lecture Notes in Computer Science(), vol 4689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74771-0_16

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  • DOI: https://doi.org/10.1007/978-3-540-74771-0_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74770-3

  • Online ISBN: 978-3-540-74771-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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