Abstract
Constructive features of tissue engineering scaffold with defect bone are defined. And based on the definitions and medical image 3D reconstructions as well as CAD technology, the constructing method for macrostructure of its interior features of tissue engineering scaffold with defect bone is presented, which is based on parametric expressions. And demonstrations of two constructing methods are given. Finally from calculations of the porosity, the structures of interior features are proven to meet the demand of porosity of tissue engineering scaffold with defect bone.
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References
Giltaij, L.R.: BMP-7 in orthopaedic applications: a review. Musculoskel. Res. 6, 55–62 (2002)
Minamide, A., Boden, S.D., Viggeswarapu, M., Hair, G.A., Oliver, C., Titus, L.: Mechanism of bone formation with gene transfer of the DNA encoding for the intracellular protein LMP-1. Bone Joint Surg. 85, 1030–1039 (2003)
Karageorgiou, V., Kaplan, D.: Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26, 5474–5491 (2005)
Elutmacher, D.W.: Scaffold design and fabrication technologies for engineering tissues – state of the art and future perspectives. Biomaterials: Sci. Polymer Edn. 12, 107–124 (2001)
Borden, M., Attawia, M., Khan, Y., Laurencin, C.T.: Tissue engineered microsphere-based matrices for bone repair, design and evaluation. Biomaterials 23, 551–559 (2002)
Sun, W., Starly, B., Nam, J., Darling, A.: Bio-CAD modeling and its applications in computer-aided tissue engineering. Computer-Aided Design 37, 1097–1114 (2005)
Shao, X.X., Hutmacher, D.W., Ho, S.T., Goh, J.C.H., Lee, E.H.: Evaluation of a hybrid scaffold/cell construct in repair of high-load-bearing osteochondral defects in rabbits. Biomaterials 27, 1071–1080 (2006)
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© 2007 Springer-Verlag Berlin Heidelberg
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Dai, C., Hu, Q., Fang, M. (2007). Parametric-Expression-Based Construction of Interior Features for Tissue Engineering Scaffold with Defect Bone. In: Li, K., Li, X., Irwin, G.W., He, G. (eds) Life System Modeling and Simulation. LSMS 2007. Lecture Notes in Computer Science(), vol 4689. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74771-0_11
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DOI: https://doi.org/10.1007/978-3-540-74771-0_11
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-74770-3
Online ISBN: 978-3-540-74771-0
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