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Tools for the Diagnosis of Renal Disease

  • Chapter
Book cover Pediatric Nephrology in the ICU

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Core Messages

  • Kidney function abnormalities are associated with increased morbidity and mortality in critically ill ICU patients.

  • Even modest increases in serum creatinine of 0.3–0.4 mg dL−1 lead to a 70% greater risk of death compared with patients without an increase.

  • Physiologic changes that occur during illness may affect solute and water handling as well as renal function. These changes can easily be assessed using a combination of readily available clinical and laboratory data or what can be considered diagnostic tools.

  • These tools can be used to do the following:

    • Determine the appropriateness of the renal response for a particular clinical circumstance.

    • Make or confirm a diagnosis.

    • Guide and monitor therapy.

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Author information

Authors and Affiliations

  1. Pediatric Nephrology, University of California, San Diego, 9500 Gilman Drive, MC 0634, La Jolla, CA, 92093, USA

    K. Mistry

  2. Division of Nephrology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA, 02115, USA

    J. T. Herrin

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  1. K. Mistry
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  2. J. T. Herrin
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Editor information

Editors and Affiliations

  1. Division of Pediatric Nephrology and Renal Transplantation, Kentucky Children's Hospital University of Kentucky, 740 South Limestone Street Room J460, Lexington, KY, 40536, USA

    Stefan G. Kiessling

  2. Nephrology and Hypertension Division Medical Director, Kidney Transplantation Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229-3039, USA

    Jens Goebel

  3. Division of Nephrology, Harvard Medical School Children's Hospital Boston, 300 Longwood Avenue, Boston, MA, 02115, USA

    Michael J. G. Somers

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Mistry, K., Herrin, J.T. (2009). Tools for the Diagnosis of Renal Disease. In: Kiessling, S.G., Goebel, J., Somers, M.J.G. (eds) Pediatric Nephrology in the ICU. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74425-2_10

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  • DOI: https://doi.org/10.1007/978-3-540-74425-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74423-8

  • Online ISBN: 978-3-540-74425-2

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