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Scanning Probe Microscopy in Biological Research

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Applied Scanning Probe Methods X

Part of the book series: Nano Science and Technolgy ((NANO))

Abstract

Scanning probe microscopy (SPM) is especially attractive to biologists, because it has the advantage of obtaining three-dimensional images of sample surfaces at high resolution not only in a vacuum but also in a nonvacuum (i. e., air or liquid) environment. In addition to the visualization of biological structures, SPM has also been applied for measuring the physical properties (i. e., viscoelasticity) of living cells, and as a manipulation tool in biomaterials. The present reviewdescribes the application of SPM to biological fields for investigating the structure and function of biomaterials from biomolecules to living cells, and shows that SPM has great potential for broadening and opening up new fields in biomedical research.

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Author information

Authors and Affiliations

  1. Graduate School of Medical and Dental Sciences, Division of Microscopic Anatomy, Niigata University, 757 Asahimachi-dori, 951-8510, Chuo-ku, Niigata, Japan

    Tatsuo Ushiki

  2. Division of Biological Sciences, Graduate School of Science, Hokkaido University, North 10 West 8, 060-0810, Kita-ku, Sapporo, Japan

    Kazushige Kawabata

Authors
  1. Tatsuo Ushiki
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  2. Kazushige Kawabata
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Editor information

Editors and Affiliations

  1. Nanotribology Laboratory for Information Storage and MEMS/NEMS (NLIM), The Ohio State University, 201W. 19th Avenue, 43210-1142, Columbus, Ohio , USA

    Bharat Bhushan

  2. Advanced Institute of Science & Technology, School of Materials Science, 923-1292, Ishikawa, Japan

    Masahiko Tomitori

  3. Institute of Physics, FB 16, University of Münster, Wilhelm-Klemm-Str. 10, 48149, Münster, Germany

    Harald Fuchs

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© 2008 Springer-Verlag Berlin Heidelberg

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Ushiki, T., Kawabata, K. (2008). Scanning Probe Microscopy in Biological Research. In: Bhushan, B., Tomitori, M., Fuchs, H. (eds) Applied Scanning Probe Methods X. Nano Science and Technolgy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74085-8_9

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