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Molecular Genetics of GAL Regulon

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Galactose Regulon of Yeast

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In general, a replica of a living or a non-living entity is called a clone. In biology, a clone refers to a progeny genetically identical to its parents. Clones are produced during vegetative or mitotic or asexual reproduction. Occasionally, during asexual reproduction, genetic variants arise at a frequency of 10−6 due to errors in copying the genetic information. Such variants are not the clone of the parent cell. In singlecelled organisms like yeast, such variants can be isolated using genetic screens or selection, and this process is called “cloning of an organism”. We have learned how to clone yeast strains that exhibit different phenotypes. Cloning multicellular organisms entails different approaches (Box 5.1.1). By definition, descendents of sexual reproduction are not clones because they are not genetically identical to the parents. This definition breaks down when one considers the haploid spores of a homo-diploid yeast cell. Here, the haploid spores produced through sexual reproduction are genetically identical to one another.

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(2008). Molecular Genetics of GAL Regulon. In: Galactose Regulon of Yeast. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74015-5_5

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