Abstract
Bioimpedance has shown potential as a method for characterising biological tissue with the use of the tetrapolar electrode configuration. This configuration has been shown to distinguish between normal squamous epithelium and Cervical Intra-epithelial Neoplasia (CIN) [1]. The tetrapolar configuration has also been shown to produce anomalous results in the form of an increase in measured impedance when a low impedance lesion is located between a drive and measurement electrode [2]. We have investigated a possible solution to this problem using bioimpedance mapping employing an array of 25 (5x5) electrodes. The array allows 64 individual tetrapolar measurements to be taken on 16 locations giving an impedance map of 49 mm2 on the surface of a tissue sample. Multiple measurements at each location reduce the chance of anomalous results since these can later be identified and excluded. Preliminary results on bovine blood have shown good separation of the measured impedance between areas of different haematocrit and provided a visual representation of the surface impedance. Impedance maps have been obtained for a range of haematocrit between 0 - 80%.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brown B H, Tidy J A, Boston K, Blackett A D, Smallwood R H and Sharp F (2000) Relation between tissue structure and imposed electrical current flow in cervical neoplasia. The Lancet 355:982-895
Smith J G, Thomas B J and Cornish B H (2004) FEA modelling: efficacy of tetrapolar electrode arrays in virtual biopsy-cervix, XII ICEBI, Gdansk, Poland, 2004, pp 313-316
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Smith, J., Thomas, B., Cornish, B. (2007). A Pilot Study For Tissue Characterisation Using Bioimpedance Mapping. In: Scharfetter, H., Merwa, R. (eds) 13th International Conference on Electrical Bioimpedance and the 8th Conference on Electrical Impedance Tomography. IFMBE Proceedings, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73841-1_40
Download citation
DOI: https://doi.org/10.1007/978-3-540-73841-1_40
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-73840-4
Online ISBN: 978-3-540-73841-1
eBook Packages: EngineeringEngineering (R0)