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Effects of Radiotherapy on Swallowing Function: Evaluation, Treatment, and Patient-Reported Outcomes

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Functional Preservation and Quality of Life in Head and Neck Radiotherapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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References

  • Aaronson NK, Ahmedzai S, Bergman B et al. (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85:365–376

    Article  PubMed  CAS  Google Scholar 

  • Aviv JE, Kim T, Sacco RL et al. (1998) FEESST: a new bedside endoscopic test of the motor and sensory components of swallowing. Ann Otol Rhinol Laryngol 107:378–387

    PubMed  CAS  Google Scholar 

  • Bjordal K, Hammerlid E, Ahlner-Elmqvist M et al. (1999) Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H & N35. J Clin Oncol 17:1008–1019

    PubMed  CAS  Google Scholar 

  • Brady SL, Hildner CD, Hutchins BF (1999) Simultaneous vid-eofl uoroscopic swallow study and modifi ed Evans blue dye procedure: an evaluation of blue dye visualization in cases of known aspiration. Dysphagia 14:146–149

    Article  PubMed  CAS  Google Scholar 

  • Campbell BH, Spinelli K, Marbella AM et al. (2004) Aspiration, weight loss, and quality of life in head and neck cancer survivors. Arch Otolaryngol Head Neck Surg 130:1100–1103

    Article  PubMed  Google Scholar 

  • Carrara-de-Angelis E, Feher O, Barros APB et al. (2003) Voice and swallowing in patients enrolled in a larynx preservation trial. Arch Otolaryngol Head Neck Surg 129:733–738

    Article  PubMed  Google Scholar 

  • Carroll WR, Locher JL, Canon CL et al. (2008) Pretreatment swallowing exercises improve swallow function after chemoradiation. Laryngoscope 118:39–43

    Article  PubMed  Google Scholar 

  • Cella DF, Tulsky DS, Gray G et al. (1993) The functional assessment of cancer therapy scale: development and validation of the general measure. J Clin Oncol 11:570–579

    PubMed  CAS  Google Scholar 

  • Chen AY, Frankowski R, Bishop-Leone J et al. (2001) The development and validation of a dysphagia-specifi c quality-of-life questionnaire for patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 127:870–876

    PubMed  CAS  Google Scholar 

  • Chen PH, Golub JS, Hapner ER et al. (2008) Prevalence of perceived dysphagia and quality-of-life impairment in a geriatric population. Dysphagia

    Google Scholar 

  • Connor NP, Cohen SB, Kammer RE et al. (2006) Impact of conventional radiotherapy on health-related quality of life and critical functions of the head and neck. Int J Radiation Oncology Biol Phys 65:1051–1062

    Google Scholar 

  • Daeffler R (1981) Oral hygiene measures for patients with cancer. Cancer Nurs 4(1):29–35

    Article  PubMed  CAS  Google Scholar 

  • Eisbruch A, Lyden T, Bradford CR et al. (2002) Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys 53:23–28

    PubMed  Google Scholar 

  • Ekberg O, Nylander G (1983) Pharyngeal dysfunction after treatment for pharyngeal cancer with surgery and radiotherapy. Gastrointest Radiol 8:97–104

    Article  PubMed  CAS  Google Scholar 

  • Epstein JB, Emerton S, Le ND et al. (1999) A double-blind crossover trial of oral balance gel and biotene toothpaste versus placebo in patients with xerostomia following radiation therapy. Oral Oncol 35(2):132–137

    Article  PubMed  CAS  Google Scholar 

  • Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), Center for Devices and Radiographic Health (CDRH) (2006) Guidance for industry patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. Health Qual Life Outcomes 4:79

    Article  Google Scholar 

  • Gillespie MB, Brodsky MB, Day TA et al. (2004) Swallowing-related quality of life after head and neck cancer treatment. Laryngoscope 114:1362–1367

    Article  PubMed  Google Scholar 

  • Hammerlid E, Silander E, Hornestam L et al. (2001) Health-related quality of life three years after diagnosis of head and neck cancer — a longitudinal study. Head Neck 23:113–125

    Article  PubMed  CAS  Google Scholar 

  • Jensen K, Lambertsen K, Grau C (2007a) Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: frequency, intensity and correlation with dose and volume parameters. Radiother Oncol 85(1):74–82

    Article  Google Scholar 

  • Jensen K, Lambertsen K, Torkov P et al. (2007b) Patient assessed symptoms are poor predictors of objective fi nd-ings. Results from cross sectional study in patients treated with radiotherapy for pharyngeal cancer. Acta Oncologica 46:1159–1168

    Article  Google Scholar 

  • Kays S, Robbins J (2006) Effects of sensorimotor exercise on swallowing outcomes relative to age and age-related disease. Semin Speech Lang 27:245–259

    Article  PubMed  Google Scholar 

  • Kuhlemeier KV, Yates P, Palmer JB (1998) Intra- and interrater variation in the evaluation of videofl uorographic swallowing studies. Dysphagia 13:142–147

    Article  PubMed  CAS  Google Scholar 

  • Kulbersh BD, Rosenthal EL, McGrew BM et al. (2006) Pretreatment, preoperative swallowing exercises may improve dysphagia quality of life. Laryngoscope 116:883–886

    Article  PubMed  Google Scholar 

  • Langmore SE, Terpenning MS, Schork A et al. (1998) Predictors of aspiration pneumonia: how important is dysphagia? Dysphagia 13:69–81

    Article  PubMed  CAS  Google Scholar 

  • Larsson M, Hedelin B, Athlin E (2003) Lived experiences of eating problems for patients with head and neck cancer during radiotherapy. J Clin Nurs 12:562–570

    Article  PubMed  Google Scholar 

  • Lawson JD, Otto K, Grist W et al. (2008) Frequency of esopha-geal stenosis after simultaneous modulated accelerated radiation therapy and chemotherapy for head and neck cancer. Am J Otolaryngol 29(1):13–19

    Article  PubMed  Google Scholar 

  • Lazarus CL, Logemann JA, Pauloski BR et al. (1996) Swallowing disorders in head and neck cancer patients treated with radiotherapy and adjuvant chemotherapy. Laryngoscope 106:1157–1166

    Article  PubMed  CAS  Google Scholar 

  • Lazarus CL, Logemann JA, Pauloski BR et al. (2000) Swallowing and tongue function following treatment for oral and oropharyngeal cancer. J Speech Lang Hear Res 43:1011–1023

    PubMed  CAS  Google Scholar 

  • Lin A, Kim HM, Terrell JE et al. (2003) Quality of life after parotid sparing IMRT for head and neck cancer: a prospective longitudinal study. Int J Radiat Oncol Biol Phys 57:61–70

    PubMed  Google Scholar 

  • Linden P, Kuhlemeier KV, Patterson C (1993) The probability of correctly predicting subglottic penetration from clinical observations. Dysphagia 8:170–179

    Article  PubMed  CAS  Google Scholar 

  • List MA, Bilir SP (2004) Functional outcomes in head and neck cancer. Semin Radiat Oncol 14:178–189

    Article  PubMed  Google Scholar 

  • List MA, Ritter-Sterr C, Lansky SB (1990) A performance status scale for head and neck cancer patients. Cancer 66:564–569

    Article  PubMed  CAS  Google Scholar 

  • Logemann JA, Pauloski BR, Rademaker AW et al. (1993) Speech and swallow function after tonsil/base of tongue resection with primary closure. J Speech Hear Res 36(5):918–926

    PubMed  CAS  Google Scholar 

  • Logemann JA, Pauloski BR, Rademaker AW et al. (1997) Speech and swallowing rehabilitation for head and neck cancer patients. Oncology 11(5):651–656, 659; discussion 659, 663–664

    PubMed  CAS  Google Scholar 

  • Logemann JA, Pauloski BR, Rademaker AW et al. (2003) Xerostomia: 12-month changes in saliva production and its relationship to perception and performance of swallow function, oral intake, and diet after chemoradiation. Head Neck 25(6):432–437

    Article  PubMed  Google Scholar 

  • Logemann JA, Smith CH, Pauloski BR et al. (2001) Effects of xerostomia on perception and performance of swallow function. Head Neck 23(4):317–321

    Article  PubMed  CAS  Google Scholar 

  • Lundy DS, Smith C, Colangelo L et al. (1999) Aspiration: cause and implications. Otolaryngol Head Neck Surg 120:474–478

    Article  PubMed  CAS  Google Scholar 

  • Madden C, Fenton J, Hughes J et al. (2000) Comparison between videofl uoroscopy and milk-swallow endoscopy in the assessment of swallowing function. Clin Otolaryngol Allied Sci 25:504–506

    Article  PubMed  CAS  Google Scholar 

  • Maurer J (1977) Providing optimal oral health. Nurs Clin North Am 12(4):671–685

    PubMed  CAS  Google Scholar 

  • McCullough GH, Wertz RT, Rosenbek JC et al. (2001) Inter- and intrajudge reliability for videofl uoroscopic swallowing evaluation measures. Dysphagia 16:110–118

    Article  PubMed  CAS  Google Scholar 

  • McHorney CA, Bricker DE, Kramer AE et al. (2000a) The SWAL-QOL outcomes tool for oropharyngeal dysphagia in adults: I. Conceptual foundation and item development. Dysphagia 15:115–121

    CAS  Google Scholar 

  • McHorney CA, Bricker DE, Robbins J et al. (2000b) The SWAL-QOL outcomes tool for oropharyngeal dysphagia in adults: II. Item reduction and preliminary scaling. Dysphagia 15:122–133

    CAS  Google Scholar 

  • Mcttorney CA, Robbins J, Lomax K et al. (2002) The SWAL-QOL and SWAL-CARE Outcomes Tool For Oropharyngeal dysphagia in adults: III. Documentation of reliability and validity. Dysphagia 17:97–114

    Article  Google Scholar 

  • Mirza N, Machtay M, Devine PA et al. (2008) Gustatory impairment in patients undergoing head and neck irradiation. Laryngoscope 118(1):24–31

    Article  PubMed  Google Scholar 

  • Morris J, Perez D, McNoe B (1998) The use of quality of life data in clinical practice. Qual Life Res 7:85–91

    Article  PubMed  CAS  Google Scholar 

  • Morton RP (2003) Studies in the quality of life of head and neck cancer patients: results of a two-year longitudinal study and a comparative cross-sectional cross-cultural study. Laryngoscope 113:1091–1103

    Article  PubMed  Google Scholar 

  • Murry T, Madasu R, Martin A et al. (1998) Acute and chronic changes in swallowing and quality of life following intraarterial chemoradiation for organ preservation in patients with advanced head and neck cancer. Head Neck 20:31–37

    Article  PubMed  CAS  Google Scholar 

  • Pauloski BR, Logemann JA (2000) Impact of tongue base and posterior pharyngeal wall biomechanics on pharyngeal clearance in irradiated postsurgical oral and oropharyn-geal cancer patients. Head Neck 22:120–131

    Article  PubMed  CAS  Google Scholar 

  • Pauloski BR, Logemann JA, Rademaker AW et al. (1993) Speech and swallowing function after anterior tongue and floor of mouth resection with distal flap reconstruction. J Speech Hear Res 36(2):267–276

    PubMed  CAS  Google Scholar 

  • Pauloski BR, Logemann JA, Rademaker AW et al. (1994) Speech and swallowing function after oral and oropharyngeal resections: one-year follow-up. Head Neck 16(4):313–322

    Article  PubMed  CAS  Google Scholar 

  • Pauloski BR, Rademaker AW, Logemann JA et al. (2000) Pretreatment swallowing function in patients with head and neck cancer. Head Neck 22:474–482

    Article  PubMed  CAS  Google Scholar 

  • Pauloski BR, Rademaker AW, Logemann JA et al. (2004) Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer. Head Neck 26(7):625–636

    Article  PubMed  Google Scholar 

  • Pauloski BR, Rademaker AW, Logemann JA et al. (2006) Relationship between swallow motility disorders on video-fl uorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy. Head Neck 28:1069–1076

    Article  PubMed  Google Scholar 

  • Peruzzi WT, Logemann JA, Currie D et al. (2001) Assessment of aspiration in patients with tracheostomies: comparison of the bedside colored dye assessment with videofl uoroscopic examination. Respir Care 46:243–247

    PubMed  CAS  Google Scholar 

  • Petruson KM, Silander EM, Hammerlid EB (2005) Quality of life as predictor of weight loss in patients with head and neck cancer. Head Neck 27:302–310

    Article  PubMed  Google Scholar 

  • Rademaker AW, Logemann JA, Pauloski BR et al. (1993) Recovery of postoperative swallowing in patients undergoing partial laryngectomy. Head Neck 15(4):325–334

    Article  PubMed  CAS  Google Scholar 

  • Rampling T, King H, Mais KL et al. (2003) Quality of life measurement in the head and neck cancer radiotherapy clinic: is it feasible and worthwhile? Clin Oncol 15:205–210

    Article  CAS  Google Scholar 

  • Robbins J, Kays SA, Gangnon RE et al. (2007) The effects of lingual exercise in stroke patients with dysphagia. Arch Phys Med Rehabil 88:150–158

    Article  PubMed  Google Scholar 

  • Robbins J, Levine R, Wood J et al. (1995) Age effects on lingual pressure generation as a risk factor for dysphagia. J Gerontol A Biol Sci Med Sci 50(5):M257–M262

    PubMed  CAS  Google Scholar 

  • Robbins JA, Gangnon RE, Theis SM et al. (2005) The effects of lingual exercise on swallowing in older adults. J Am Geriatr Soc 53:1483–1489

    Article  PubMed  Google Scholar 

  • Schattner M (2003) Enteral nutritional support of the patient with cancer: route and role. J Clin Gastroenterol 36(4):297–302

    Article  PubMed  Google Scholar 

  • Smith CH, Logemann JA, Colangelo LA et al. (1999) Incidence and patient characteristics associated with silent aspiration in the acute care setting. Dysphagia 14:1–7

    Article  PubMed  CAS  Google Scholar 

  • Terrell JE, Nanavati KA, Esclamado RM et al. (1997) Head and neck cancer-specifi c quality of life: instrument validation. Arch Otolaryngol Head Neck Surg 123:1125–1132

    PubMed  CAS  Google Scholar 

  • Ware JE, Jr, Sherbourne CD (1992) The MOS 36-Item Short-Form Health Survey (SF-36): I. Conceptual framework and item selection. Med Care 30:473–483

    Article  PubMed  Google Scholar 

  • Wiklund A (2004) Assessment of patient-reported outcomes in clinical trials: the example of health-related quality of life. Fundam Clin Pharmacol 18:351–363

    Article  PubMed  CAS  Google Scholar 

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Knigge, M., Kammer, R., Connor, N.P. (2009). Effects of Radiotherapy on Swallowing Function: Evaluation, Treatment, and Patient-Reported Outcomes. In: Harari, P.M., Connor, N.P., Grau, C. (eds) Functional Preservation and Quality of Life in Head and Neck Radiotherapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73232-7_23

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  • DOI: https://doi.org/10.1007/978-3-540-73232-7_23

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