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Characterizing Reduction Graphs for Gene Assembly in Ciliates

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Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 4588))

Abstract

The biological process of gene assembly has been modeled based on three types of string rewriting rules, called string pointer rules, defined on so-called legal strings. It has been shown that reduction graphs, graphs that are based on the notion of breakpoint graph in the theory of sorting by reversal, for legal strings provide valuable insights into the gene assembly process. We characterize which legal strings obtain the same reduction graph (up to isomorphism), and moreover we characterize which graphs are (isomorphic to) reduction graphs.

This research was supported by the Netherlands Organization for Scientific Research (NWO) project 635.100.006 “VIEWS”.

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References

  1. Cavalcanti, A., Clarke, T., Landweber, L.: MDS_IES_DB: a database of macronuclear and micronuclear genes in spirotrichous ciliates. Nucleic Acids Res. 33, D396–D398 (2005)

    Article  Google Scholar 

  2. Brijder, R., Hoogeboom, H., Rozenberg, G.: Reducibility of gene patterns in ciliates using the breakpoint graph. Theor. Comput. Sci. 356, 26–45 (2006)

    Article  MATH  MathSciNet  Google Scholar 

  3. Brijder, R., Hoogeboom, H., Rozenberg, G.: The breakpoint graph in ciliates. In: Berthold, M.R., Glen, R.C., Diederichs, K., Kohlbacher, O., Fischer, I. (eds.) CompLife 2005. LNCS (LNBI), vol. 3695, pp. 128–139. Springer, Heidelberg (2005)

    Chapter  Google Scholar 

  4. Hannenhalli, S., Pevzner, P.: Transforming cabbage into turnip: Polynomial algorithm for sorting signed permutations by reversals. J. ACM 46, 1–27 (1999)

    Article  MATH  MathSciNet  Google Scholar 

  5. Bergeron, A., Mixtacki, J., Stoye, J.: On sorting by translocations. In: Miyano, S., Mesirov, J., Kasif, S., Istrail, S., Pevzner, P., Waterman, M. (eds.) Research in Computational Molecular Biology. LNCS (LNBI), vol. 3500, pp. 615–629. Springer, Heidelberg (2005)

    Google Scholar 

  6. Setubal, J., Meidanis, J.: Introduction to Computional Molecular Biology. PWS Publishing Company, London (1997)

    Google Scholar 

  7. Brijder, R., Hoogeboom, H., Muskulus, M.: Strategies of loop recombination in ciliates. LIACS Technical Report 2006-01, [arXiv:cs.LO/0601135] (2006)

    Google Scholar 

  8. Brijder, R., Hoogeboom, H., Muskulus, M.: Applicability of loop recombination in ciliates using the breakpoint graph. In: Berthold, M.R., Glen, R.C., Fischer, I. (eds.) CompLife 2006. LNCS (LNBI), vol. 4216, pp. 97–106. Springer, Heidelberg (2006)

    Chapter  Google Scholar 

  9. Brijder, R., Hoogeboom, H.: The fibers and range of reduction graphs in ciliates. LIACS Technical Report 2007-01, [arXiv:cs.LO/0702041] (2007)

    Google Scholar 

  10. Ehrenfeucht, A., Harju, T., Petre, I., Prescott, D., Rozenberg, G.: Computation in Living Cells – Gene Assembly in Ciliates. Springer Verlag, Heidelberg (2004)

    MATH  Google Scholar 

  11. Pevzner, P.: Computational Molecular Biology: An Algorithmic Approach. MIT Press, Cambridge (2000)

    MATH  Google Scholar 

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Tero Harju Juhani Karhumäki Arto Lepistö

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© 2007 Springer-Verlag Berlin Heidelberg

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Brijder, R., Hoogeboom, H.J. (2007). Characterizing Reduction Graphs for Gene Assembly in Ciliates. In: Harju, T., Karhumäki, J., Lepistö, A. (eds) Developments in Language Theory. DLT 2007. Lecture Notes in Computer Science, vol 4588. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73208-2_14

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  • DOI: https://doi.org/10.1007/978-3-540-73208-2_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-73207-5

  • Online ISBN: 978-3-540-73208-2

  • eBook Packages: Computer ScienceComputer Science (R0)

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