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CT- and MR-Guided Interventions in Radiology pp 311–348Cite as

Musculo-Skeletal Interventions

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Abstract

Osteoid osteoma is a benign bone tumor which was first described by Jaffe (1935). Histologically it consists of a centrally located nidus composed of osteoblasts and osteoid which is surrounded by an area of reactive sclerosis and/or periosteal new bone formation. Prostaglandins which are produced by the tumor induce a chronic inflammatory reaction and vasodilatation which results in stimulation of unmyelinated nerve endings in the nidus causing pain. This leads to the clinical symptoms of this lesion with local pain often worsening during the night, which is typically relieved by aspirin or other related nonsteroidal antiinflammatory drugs. Osteoid osteomas occurmore frequently in men than in women (2:1) and most patients, approximately 75%, suffering from osteoid osteomas are between 5 and 25 years old. Most commonly osteoid osteomas are found in the diaphysis of femur and tibia followed by humerus, radius, ulna, hand, and the verterbral spine. A malignant transformation of osteoid osteoma is not known.

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References

Section 15.1

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Authors and Affiliations

  1. Applied Medical Engineering, Helmholtz-Institute, RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany

    Philipp Bruners

  2. Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelsstraße 30, 52074, Aachen, Germany

    Andreas H. Mahnken & Gabriele A. Krombach

  3. Department of Radiology, University Hospital Bonn, Sigmund-Freud-Straße 25, 53127, Bonn, Germany

    Kai Wilhelm

  4. Interventional Radiology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland

    Sebastian Kos, Deniz Bilecen & Augustinus Ludwig Jacob

  5. Emergency and Trauma Center, Rashid Hospital, PO Box 4545, Dubai, United Arab Emirates

    Peter Messmer

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  1. Philipp Bruners
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  2. Andreas H. Mahnken
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  3. Kai Wilhelm
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  4. Sebastian Kos
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  5. Peter Messmer
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  6. Deniz Bilecen
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  7. Augustinus Ludwig Jacob
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  8. Gabriele A. Krombach
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Editors and Affiliations

  1. Department of Diagnostic Radiology, University Hospital, RWTH Aachen University, Pauwelstrasse 30, 52074, Aachen, Germany

    Andreas H. Mahnken

  2. Department of Radiology and Nuclear Medicine, University Hospital Magdeburg, Leipziger Straße 44, 39120, Magdeburg, Germany

    Jens Ricke

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© 2009 Springer-Verlag Berlin Heidelberg

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Bruners, P. et al. (2009). Musculo-Skeletal Interventions. In: Mahnken, A., Ricke, J. (eds) CT- and MR-Guided Interventions in Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-73085-9_15

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  • DOI: https://doi.org/10.1007/978-3-540-73085-9_15

  • Publisher Name: Springer, Berlin, Heidelberg

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