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Variable-Range Charge Hopping in DNA

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Charge Migration in DNA

Part of the book series: NanoScience and Technology ((NANO))

Abstract

In Chap. 3, Berlin and Ratner describe charge migration in DNA within a theoretical framework of a variable-range hopping model which has been successfully used to analyze steady-state measurements of the charge transfer efficiency for this molecule. According to the model proposed, the ability of DNA to serve as the medium for very long-range (up to 200 – 300°A) charge transfer is caused by the energetics of the base pairs stacked in the interior of the double helix. The energy landscape for charge migration along the stack of the nucleobases is shown to exhibit features typical for complex disordered systems. They also show that a charge moving in this landscape can be transferred over large distances via a series of short quantum hops with typical length of 13 — 18°A alternating with relatively long thermally activated jumps between “resting” sites of the stack. The physical nature of the hopping charges and the issues of dynamic and static disorder are also discussed in the context of the transport properties of DNA systems.

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Authors and Affiliations

  1. Department of Chemistry, Center for Nanofabrication and Molecular Self-Assembly, and Materials Research Center, Northwestern University, 2145 Sheridan Road, Evanston, Illinois, 60208-3113, USA

    Yuri A. Berlin & Mark A. Ratner

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  1. Yuri A. Berlin
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  1. Department of Physics and Astronomy, Canada Research Chair in Nanoscale Physics, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada

    Tapash Chakraborty

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Berlin, Y.A., Ratner, M.A. (2007). Variable-Range Charge Hopping in DNA. In: Chakraborty, T. (eds) Charge Migration in DNA. NanoScience and Technology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72494-0_3

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