Abstract
This special issue gives an overview of the current state-of-the-art of creating a bioengineered pacemaker. The subject has potential clinical interest. Indeed, electronic pacemakers currently available have several limitations, among which inadequate rate adaptation to physiological needs, problems related to the stimulating and sensing leads and infection of the pacemaker pocket, which might be overcome by a bio-pacemaker. Generation of a bio-pacemaker has also scientific interest, because it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well.
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de Bakker, J.M.T., Zaza, A. (2007). Biopacemaking: Clinically Attractive, Scientifically a Challenge. In: Spaan, J.A.E., Coronel, R., de Bakker, J.M.T., Zaza, A. (eds) Biopacemaking. Series in Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72110-9_1
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DOI: https://doi.org/10.1007/978-3-540-72110-9_1
Publisher Name: Springer, Berlin, Heidelberg
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