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MRI Atlas of MS Lesions pp 145–173Cite as

Differential Diagnosis of Multiple Sclerosis

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Abstract

The signs and symptoms related to MS are diverse and white matter abnormalities on MRI are not specific. In a small number of patients with MS brain MRI may be normal and in others it may show diffuse, large or atypical lesions. As there is no paraclinical test that is pathognomonic for MS and many conditions can mimic this disease clinically or radiologically, the new Mc Donald’s criteria still insist on the exclusion of alternative conditions for correct diagnosis of MS (Polman et al. 2005). In fact, diagnosis of MS is based on showing disease dissemination in space and time and on the exclusion of other diseases that may explain the neurological symptoms of the patients.

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Author information

Authors and Affiliations

  1. Neurological Institute, Head of Department of Neurology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Jun-Ichi Kira

  2. Department of Neuroradiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland

    Sabine Haller

  3. Head of Department of Neurology and Neurorehabilitation Center, 7317, Valens, Switzerland

    Jürg Kesselring

  4. Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Hassan Abad Square, Tehran, Iran, Islamic Republic of

    Mohammad Ali Sahraian

Authors
  1. Jun-Ichi Kira
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  2. Sabine Haller
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  3. Jürg Kesselring
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  4. Mohammad Ali Sahraian
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Editor information

Editors and Affiliations

  1. Head of Department of Neuroradiology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland

    Ernst-Wilhelm Radü

  2. Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Hassan Abad Square, Tehran, Iran, Islamic Republic of

    Mohammad Ali Sahraian

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© 2007 Springer-Verlag Berlin Heidelberg

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Kira, JI., Haller, S., Kesselring, J., Sahraian, M. (2007). Differential Diagnosis of Multiple Sclerosis. In: Radü, EW., Sahraian, M. (eds) MRI Atlas of MS Lesions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71372-2_9

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  • DOI: https://doi.org/10.1007/978-3-540-71372-2_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-71371-5

  • Online ISBN: 978-3-540-71372-2

  • eBook Packages: MedicineMedicine (R0)

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