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Neuropsychologie der Schizophrenie pp 155–165Cite as

Wahrnehmung — Bildgebung

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Die Schizophrenie ragt unter den neuropsychiatrischen Störungen in Bezug auf die defizitäre auditorische Verarbeitung hervor, sodass funktionelle Bildgebungsdaten des auditorischen Systems zur Formulierung von neuen Hypothesen gemäß der zugrunde liegenden Pathophysiologie beitragen können (⊡ Abb. 14.1). Die Phänomenologie, deren charakteristische positive Symptome der Psychose, Halluzinationen (meist verbalauditorisch), Wahn und formale Denkstörungen, weisen auf den linken Temporallappen als gestörte Struktur hin, was vom klassischen neuropathologischen Blickpunkt aus früh diskutiert wurde (siehe Kraepelin 1919). Strukturelle Abweichungen des Temporallappens, seiner Form und seines Volumens wurden wiederholt bei Patienten mit Schizophrenie beschrieben (Suddath et al. 1989). Einige Abweichungen wurden insbesondere nahe dem auditorischen Kortex in

Schema der aufsteigenden auditorischen Pfade von der Cochlea bis zum primären auditorischen Kortex. Die Überlagerung auf einem Profilschnitt durch einen MR-Datensatz gibt einen Eindruck der anatomischen Verhältnisse. Im auditorischen System beginnt die bilaterale Verarbeitung sehr früh. Die Kerngruppen im Hirnstamm und Thalamus tragen zu Verarbeitungsschritten bei, in denen räumliche, spektrale und dynamische Muster extrahiert werden. Vom Thalamus existieren direkte Bahnen zum primären und auch zum sekundären auditorischen Kortex. Der primäre auditorische Kortex liegt vorwiegend auf der heschlschen Querwindung. Sekundäre und Assoziationskortizes sind um diesen herum organisiert. (Mathiak, Universität Tübingen, 2004) (▸ Farbtafeln, S. 650).

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Authors and Affiliations

  1. Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum der RWTH Aachen, Pauwelsstraße 30, 52074, Aachen

    Heike Thönnessen (Dipl.-Psych.) & Klaus Mathiak (Prof. Dr. med. Dr. rer. nat.)

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  1. Heike Thönnessen
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  2. Klaus Mathiak
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Thönnessen, H., Mathiak, K. (2008). Wahrnehmung — Bildgebung. In: Neuropsychologie der Schizophrenie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-71147-6_14

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  • DOI: https://doi.org/10.1007/978-3-540-71147-6_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-71146-9

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