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The Cytoskeleton and Polarized Growth of Filamentous Fungi

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Biology of the Fungal Cell

Part of the book series: The Mycota ((MYCOTA,volume 8))

Abstract

Polarized growth is the mechanism by which filamentous fungi extend their hyphae. Microtubules (MT) and filamentous actin (F-actin), in combination with their corresponding motor proteins, kinesin, dynein and myosin, play important roles in this process. Actin has an essential role for tip elongation and septation. It is required for vesicle secretion and cell wall extension, and possibly - together with the MT cytoskeleton - for the localization of so-called cell end marker or landmark proteins, which control growth directionality. The exact contribution of the MT cytoskeleton on polarized growth is less clear. Genetic, biochemical and cell biological approaches in Aspergillus nidulans and other fungi led to a modified view of many MT-related aspects within the past few years. There is increasing evidence that MT cables, which are visualized by immunostaining or GFP-tubulin fusion proteins, consist of several MTs and their dynamics appears to be different in fast-growing hyphal tips as compared with young germlings.

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Authors and Affiliations

  1. Max-Planck-Institute for terrestrial Microbiology, Karl-von-Frisch-Str., D-35043, Marburg, Germany

    R. Fischer

  2. Institute for Applied Biosciences, Dept. of Applied Microbiology, University of Karlsruhe, Hertzstrasse 16, D-76187, Karlsruhe, Germany

    R. Fischer

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  1. R. Fischer
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Editors and Affiliations

  1. DuPont Crop Genetics, Experimental Station E353 Powder Mill Road, Wilmington, DE, 19880-0353, USA

    Richard J. Howard

  2. School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK

    Neil A. R. Gow

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© 2007 Springer-Verlag Berlin Heidelberg

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Fischer, R. (2007). The Cytoskeleton and Polarized Growth of Filamentous Fungi. In: Howard, R.J., Gow, N.A.R. (eds) Biology of the Fungal Cell. The Mycota, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70618-2_5

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