Abstract
We propose an approach for analyzing tree-like structures in biomedical images. Our analysis is based on Vector Quantization (VQ), an image compression technique. Here, we approach VQ from a different perspective: we use the histogram of the codeword usage as a feature vector representing the initial image. As ductal tree topology has predictive value for a variety of diseases, such as papilloma, ductal ectasia, and ductal carcinoma, we chose to apply this technique to compare texture of the breast ductal tree in x-ray galactograms against the same tissue in corresponding unenhanced mammograms, which do not visualize the ductal tree. We also investigate the relationship between texture and the underlying ductal branching topology using descriptors adapted from the data mining literature. We believe that our method has the potential to assist the interpretation of clinical images and deepen our understanding of relationships among structure, texture, function, and pathology.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bullitt, E., Zeng, D., Gerig, G., Aylward, S., Joshi, S., Smith, J.K., Lin, W., Ewend, M.G.: Vessel Tortuosity and Brain Tumor Malignancy: A Blinded Study. Academic Radiology 12, 1232–1240 (2005)
Pereira, B., Mokbel, K.: Mammary ductoscopy: past, present, and future. International Journal on Clinical Oncology 10, 112–116 (2005)
Vannimenus, J., Viennot, X.G.: Combinatorial tools for the analysis of ramified patterns. Journal of Statistical Physics 54, 1529–1538 (1989)
Bakic, P.R., Albert, M., Brzakovic, D., Maidment, A.D.: Mammogram synthesis using a three-dimensional simulation. III. Modeling and evaluation of the breast ductal network. Medical Physics 30, 1914–1925 (2003)
Bakic, P.R., Albert, M., Maidment, A.D.: Classification of galactograms with ramification matrices: preliminary results. Academic Radiology 10, 198–204 (2003)
Kontos, D., Megalooikonomou, V., Javadi, A., Bakic, P., Maidment, A.: Classification of Galactograms Using Fractal Properties of the Breast Ductal Network. In: Proc. of the IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Arlington, Virginia (2006)
Megalooikonomou, V., Kontos, D., Danglemaier, J., Javadi, A., Bakic, P., Maidment, A.D.A.: A representation and classification scheme for tree-like structures in medical images: An application on branching pattern analysis of ductal trees in x-ray galactograms. In: Proceedings of the SPIE Conference on Medical Imaging, San Diego, California, February 2006, vol. 6144, 61441H (2006)
Sholl, D.A.: Dendritic Organization in the Neurons of the Visual and Motor Cortices of the Cat. Journal of Anatomy 87, 387–406 (1953)
Author information
Authors and Affiliations
Editor information
Rights and permissions
Copyright information
© 2008 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Barnathan, M., Zhang, J., Kontos, D., Bakic, P., Maidment, A., Megalooikonomou, V. (2008). Analyzing Tree-Like Structures in Biomedical Images Based on Texture and Branching: An Application to Breast Imaging. In: Krupinski, E.A. (eds) Digital Mammography. IWDM 2008. Lecture Notes in Computer Science, vol 5116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70538-3_4
Download citation
DOI: https://doi.org/10.1007/978-3-540-70538-3_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-70537-6
Online ISBN: 978-3-540-70538-3
eBook Packages: Computer ScienceComputer Science (R0)