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Sentinel Node Concept

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Management of Breast Diseases

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Abstract

Some form of axillary surgery is an integral component in the locoregional management of early breast cancer. Surgical techniques have become progressively less extensive over the past 30 years in terms of both parenchymal and nodal resection of breast and axillary tissues, respectively. Despite the widespread introduction of breast conservation surgery (BCS), a formal axillary lymph node dissection (ALND) was, until recently, the standard procedure of choice for the management of the axilla in the majority of patients irrespective of primary tumour characteristics. Breast screening programmes and heightened public awareness have led to smaller tumour size at presentation and a lower proportion of patients with nodal involvement. Approximately 25–30% of patients now have nodal disease at the time of diagnosis compared with 50% two decades ago [1]. For those patients with positive nodes, removal of axillary nodes containing tumour foci minimises the chance of locoregional relapse and can provide crucial information for guiding systemic adjuvant treatments.

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Authors and Affiliations

  1. Cambridge Breast Unit, Addenbrooke’s Hospital, Hills Road, Cambridge, CB2 0QQ, UK

    John R. Benson

  2. Second Department of Surgery, University of Athens Medical School, 76 Vassilis Sofias Avenue, 11528, Athens, Greece

    Vassilis Pitsinis

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  2. Vassilis Pitsinis
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Correspondence to John R. Benson .

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  1. Breast Care Center National Naval Medical Center, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA

    Ismail Jatoi (Head) (Head)

  2. Women’s Hospital, University of Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany

    Manfred Kaufmann (Breast Unit Director) (Breast Unit Director)

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Benson, J.R., Pitsinis, V. (2010). Sentinel Node Concept. In: Jatoi, I., Kaufmann, M. (eds) Management of Breast Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69743-5_14

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