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Neural Control of Ocular Blood Flow

  • Anton ReinerEmail author
  • Malinda E. C. Fitzgerald
  • Chunyan Li
Chapter

Core Messages

  • Neural regulation of ocular blood flow is mediated by parasympathetic, sympathetic and sensory innervation of ocular and orbital blood vessels.

  • The parasympathetic, and sympathetic inputs to ocular vessels are controlled by central nervous system circuitry that is responsive to interoceptive and exteroceptive stimuli.

  • The parasympathetic input to choroid appears to maintain high ocular blood flow during low systemic blood pressure, and may also mediate increased blood flow in response to increased retinal activity.

  • The sympathetic input to choroid appears to prevent excessive ocular blood flow during systemic hypertension.

  • Impaired autonomic control of choroidal blood flow leads to retinal pathology and dysfunction.

  • Impairments in the neural control of choroidal blood flow occur with aging, and various ocular or systemic diseases such as glaucoma, age-related macular degeneration, hypertension and diabetes, and such impairments in neural control of choroidal blood flow...

Keywords

Nitric Oxide Vasoactive Intestinal Polypeptide Lacrimal Gland Ciliary Body Central Retinal Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Anton Reiner
    • 1
    Email author
  • Malinda E. C. Fitzgerald
    • 2
    • 3
  • Chunyan Li
    • 1
  1. 1.Department of Anatomy and NeurobiologyUniversity of Tennessee Health Science CenterMemphisUSA
  2. 2.Department of Anatomy and Neurobiology and OphthalmologyUniversity of Tennessee Health Science CenterMemphisUSA
  3. 3.Department of BiologyChristian Brothers UniversityMemphisUSA

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