Abstract
Devices for time-domain optical coherence tomography and, more recently, spectral-domain optical coherence tomography (spectral OCT) with an improved depth resolution of 7 μm (27,000–400,000 scans per second) carry out a noninvasive and in vivo visualization of the retinal layers, particularly the outer nuclear layer (ONL), the photoreceptor inner segment/outer segment junction (IS/OS), and the retinal pigment epithelium (RPE). Hence, the integrity or abnormality of the retinal pigment epithelium, the inner/outer segment junction, and the external limiting membrane can be assessed and graduated even during early stages of inherited retinal diseases, when the fundus appears normal on examination.
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Meunier, I. et al. (2014). Spectral-Domain Optical Coherence Tomography in Hereditary Retinal Dystrophies. In: Puech, B., De Laey, JJ., Holder, G. (eds) Inherited Chorioretinal Dystrophies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69466-3_7
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DOI: https://doi.org/10.1007/978-3-540-69466-3_7
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