Abstract
Alport syndrome (AS) is a progressive haematuric nephritis, associated with high tone sensorineural deafness and inconstant ocular involvement first described as a dominantly inherited disorder in 1927 [1]. The eyes may present microphthalmia, a polymorph posterior corneal dystrophy, a subcapsular cataract, a bilateral and progressive anterior or posterior lenticonus and a dot-like peripheral retinal dystrophy with macular degeneration (Fig. 41.1).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Alport AC. Hereditary familial congenital haemorrhagic nephritis. Br Med J. 1927;I:504–6.
Aslanzadeh GA, Gharabaghi D, Naderi N. Clear lens phacoemulsification in the anterior lenticonus due to Alport Syndrome: two case reports. J Med Case Reports. 2008;2:178.
Govan JA. Ocular manifestations of Alport’s syndrome: a hereditary disorder of basement membranes? Br J Ophthalmol. 1983;67:493–503.
Hentati N, Sellami D, Makni K, Kharrat M, Hachicha J, Hammadi A, Feki J. Atteinte oculaire au cours du syndrome d’Alport. A propos de 32 cas. J Fr Ophtalmol. 2008;31:597–604.
McCarthy PA, Maino DM. Alport syndrome: a review. Clin Eye Vis Care. 2000;12:139–50.
Setâlä K, Ruusuvaara P. Alport syndrome with hereditary macular degeneration. Acta Ophthalmol. 1989;67:409–14.
Ramesh Saxena. Alport syndrome. http://www.emedicine.com/med/topic110.htm. 2008.
Teekhasaenee C, Nimmanit S, Wutthiphan S, Vareesangthip K, Laohapand T, Malasitr P, Ritch R. Posterior polymorphous dystrophy and Alport syndrome. Ophthalmology. 1991;98:1207–15.
Yasuzumi K, Futagami S, Kiyosawa M, Mochizuki M. Bilateral serous retinal detachment associated with Alport’s syndrome. Ophthalmologica. 2000;214:301–4.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Puech, B., De Laey, JJ. (2014). Alport Syndrome. In: Puech, B., De Laey, JJ., Holder, G. (eds) Inherited Chorioretinal Dystrophies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69466-3_41
Download citation
DOI: https://doi.org/10.1007/978-3-540-69466-3_41
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-69464-9
Online ISBN: 978-3-540-69466-3
eBook Packages: MedicineMedicine (R0)