Abstract
Acute kidney injury (AKI) is a serious complication in cancer patients Multiple causes such as metabolic disturbances, tumor lysis syndrome, renal infiltration by malignant cells, sepsis, or drug-induced toxicity may lead to AKI in cancer patients In some cases, cancer treatment is the main cause of AKI
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Benoit DD, Depuydt PO, Vandewoude KH, Offner FC, Boterberg T, De Cock CA, Noens LA, Janssens AM, Decruyenaere JM: Outcome in critically ill medical patients treated with renal replacement therapy for Acute Kidney Injury: comparison between patients with and those without haematological malignancies. Nephrol Dial Transplant 2005; 20:552–558.
Darmon M, Thiery G, Ciroldi M, de Miranda S, Galicier L, Raffoux E, Le Gall JR, Schlemmer B, Azoulay E: Intensive care in patients with newly diagnosed malignancies and a need for cancer chemotherapy. Crit Care Med 2005; 33:2488–2493.
Bagshaw SM, Laupland KB, Doig CJ, Mortis G, Fick GH, Mucenski M, Godinez-Luna T, Svenson LW, Rosenal T: Prognosis for long-term survival and renal recovery in Âcritically ill patients with severe Acute Kidney Injury: a population-based study. Crit Care 2005; 9:R700–R709.
Markowitz GS, Appel GB, Fine PL, Fenves AZ, Loon NR, Jagannath S, et al. Collapsing focal segmental glomerulosclerosis following treatment with high-dose pamidronate. J Am Soc Nephrol. 2001; 12:1164–1172.
Markowitz GS, Fine PL, Stack JI, Kunis CL, Radhakrishnan J, Palecki W, et al. Toxic acute tubular necrosis following Âtreatment with zoledronate (Zometa). Kidney Int. 2003; 64:281–289.
Quesada JR, Talpaz M, Rios A, Kurzrock R, Gutterman JU. Clinical toxicity of interferons in cancer patients: a review. J Clin Oncol. 1986; 4:234–243.
Zuber J, Martinez F, Droz D, Oksenhendler E, Legendre C. Alpha-interferon-associated thrombotic microangiopathy: a clinicopathologic study of 8 patients and review of the literature. Medicine (Baltimore). 2002; 81:321–331.
Cantrell JE, Jr., Phillips TM, Schein PS. Carcinomaassociated hemolytic-uremic syndrome: a complication of mitomycin C chemotherapy. J Clin Oncol. 1985; 3:723–734.
Valavaara R, Nordman E. Renal complications of mitomycin C therapy with special reference to the total dose. Cancer. 1985; 55:47–50.
Fung MC, Storniolo AM, Nguyen B, Arning M, Brookfield W, Vigil J. A review of hemolytic uremic syndrome in patients treated with gemcitabine therapy. Cancer. 1999; 85:2023–2032.
Arany I, Safirstein RL: Cisplatin nephrotoxicity. Semin Nephrol 2003; 23:460–464.
Schuchter LM, Hensley ML, Meropol NJ, Winer EP, American Society of Clinical Oncology Chemotherapy and Radiotherapy Expert Panel: 2002 update of recommendations for the use of chemotherapy and radiotherapy protectants: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2002; 20:2895–2903.
Arany I, Safirstein RL: Cisplatin nephrotoxicity. Semin Nephrol 2003; 23:460–464.
Widemann BC, Balis FM, Kempf-Bielack B, Bielack S, Pratt CB, Ferrari S, Bacci G, Craft AW, Adamson PC: High-dose methotrexate- induced nephrotoxicity in patients with osteosarcoma. Cancer 2004; 100:2222–2232.
Relling MV, Stapleton FB, Ochs J, Jones DP, Meyer W, Wainer IW, et al. Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion. Cancer. 1988; 62:884–888.
Wall SM, Johansen MJ, Molony DA, DuBose TD, Jr., Jaffe N, Madden T. Effective clearance of methotrexate using high-flux hemodialysis membranes. Am J Kidney Dis. 1996; 28: 846–854.
Buchen S, Ngampolo D, Melton RG, Hasan C, Zoubek A, Henze G, Bode U, Fleischhack G: Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure. Br J Cancer 2005; 92:480–487.
Suarez A, McDowell H, Niaudet P, Comoy E, Flamant F: Longterm follow-up of ifosfamide renal toxicity in children treated for malignant mesenchymal tumors: an International Society of Pediatric Oncology report. J Clin Oncol 1991; 9:2177–2182.
Andreoli SP, Clark JH, Mcguire WA, Bergstein JM. Purine excretion during tumour lysis in children with acute Âlymphocytic leukaemia receiving allopurinol: relationship to Acute Kidney Injury. J Pediatr. 1986; 109:292–298.
Brogard JM, Coumaros D, Franckhauser J, Stahl A, Stahl J. Enzymatic uricolysis: a study of the effect of a fungal urateoxydase. Rev Eur Etud Clin Biol. 1972; 17:890–895.
Mahmoud HH, Leverger G, Patte C, Harvey E, Lascombes F. Advances in the management of malignancy-associated hyperuricaemia. Br J Cancer. 1998; 77:18–20.
Verdecchia P, Schillaci G, Reboldi GP, Santeusanio F, Porcellati C, Brunetti P. Relation between serum uric acid and risk of cardiovascular disease in essential ÂhyperÂtension: the PIUMA Study. Hypertension. 2000; 36:1072–1078.
Johnson WJ, Kyle RA, Pineda AA, O’Brien PC, Holley KE. Treatment of renal failure associated with multiple myeloma. Plasmapheresis, hemodialysis, and chemotherapy. Arch Intern Med. 1990; 150:863–869.
Alexanian R, Barlogie B, Dixon D. Renal failure in multiple myeloma. Arch Intern Med. 1990; 150:1693–1695.
Reiter E, Kalhs P, Keil F, Rabitsch W, Gisslinger H, Mayer G, et al. Effect of high-dose melphalan and peripheral blood stem cell transplantation on renal function in patients with multiple myeloma and renal insufficiency: a case report and review of the literature. Ann Hematol. 1999; 78:189–191.
Smith DM, Weisenburger DD, Bierman P, Kessinger A, Vaughan WP, Armitage JO. Acute Kidney Injury associated with autologous bone marrow transplantation. Bone Marrow Transplant. 1987; 2:195–210.
Kennedy MS, Deeg HJ, Siegel M, Crowley JJ, Storb R, Thomas ED. Acute renal toxicity with combined use of amphotericin B and cyclosporine after marrow transplantation. Transplantation. 1983; 35:211–215.
McDonald GB, Hinds MS, Fisher LD, Schoch HG, Wolford JL, Banaji M, Hardin BJ, Shulman HM, Clift RA: Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients. Ann Intern Med 1993; 118:255–267.
Mori K, Yoshihara T, Nishimura Y, Uchida M, Katsura K, Kawase Y, Hatano I, Ishida H, Chiyonobu T, Kasubuchi Y, et al.: AKI due to adenovirus-associated obstructive uropathy and necrotizing tubulointerstitial nephritis in a bone marrow transplant recipient. Bone Marrow Transplant 2003; 31: 1173–1176.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Ronco, C. (2010). Acute Kidney Injury in Oncological Disorders and Tumor Lysis Syndrome. In: Jörres, A., Ronco, C., Kellum, J. (eds) Management of Acute Kidney Problems. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69441-0_41
Download citation
DOI: https://doi.org/10.1007/978-3-540-69441-0_41
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-69413-7
Online ISBN: 978-3-540-69441-0
eBook Packages: MedicineMedicine (R0)