Skip to main content

Long-Term Outcome of Acute Kidney Injury

  • Chapter
  • First Online:
Management of Acute Kidney Problems

Abstract

Hospital survival of acute kidney injury (AKI): requiring RRT 38–58% 1-year survival of AKI: 21–53% 5-year survival of AKI: 15–52% 80–90% of surviving patients do not require further renal replacement therapy Most patients surviving AKI report satisfying quality of life History of chronic renal disease is the major risk factor for dialysis dependency after AKI

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ahlstrom A, Tallgren M, Peltonen S, Rasanen P, Pettila V (2005) Survival and quality of life of patients requiring acute renal replacement therapy. Intensive Care Med 31: 1222–1228

    Article  PubMed  Google Scholar 

  2. Arabi Y, Ahmed QA, Haddad S, Aljumah A, Al Shimemeri A (2004) Outcome predictors of cirrhosis patients admitted to the intensive care unit. Eur J Gastroenterol Hepatol 16: 333–339

    Article  PubMed  Google Scholar 

  3. Bagshaw SM, George C, Bellomo R (2008) Early acute kidney injury and sepsis: a multicentre evaluation. Crit Care 12: R47

    Article  PubMed  Google Scholar 

  4. Bagshaw SM, Laupland KB, Doig CJ, Mortis G, Fick GH, Mucenski M, Godinez-Luna T, Svenson LW, Rosenal T (2005) Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study. Crit Care 9: R700–R709

    Article  PubMed  Google Scholar 

  5. Bagshaw SM, Mortis G, Doig CJ, Godinez-Luna T, Fick GH, Laupland KB (2006) One-year mortality in critically ill patients by severity of kidney dysfunction: a population-based assessment. Am J Kidney Dis 48: 402–409

    Article  PubMed  Google Scholar 

  6. Bell M, Granath F, Schon S, Ekbom A, Martling CR (2007) Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure. Intensive Care Med 33: 773–780

    Article  PubMed  Google Scholar 

  7. Benoit DD, Vandewoude KH, Decruyenaere JM, Hoste EA, Colardyn FA (2003) Outcome and early prognostic indicators in patients with a hematologic malignancy admitted to the intensive care unit for a life-threatening complication. Crit Care Med 31: 104–112

    Article  PubMed  Google Scholar 

  8. Bhandari S, Turney JH (1996) Survivors of acute renal failure who do not recover renal function. QJM 89: 415–421

    CAS  PubMed  Google Scholar 

  9. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16: 3365–3370

    Article  PubMed  Google Scholar 

  10. Clermont G, Acker CG, Angus DC, Sirio CA, Pinsky MR, Johnson JP (2002) Renal failure in the ICU: comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. Kidney Int 62: 986–996

    Article  PubMed  Google Scholar 

  11. Cole L, Bellomo R, Silvester W, Reeves JH (2000) A prospective, multicenter study of the epidemiology, management, and outcome of severe acute renal failure in a “closed” ICU system. Am J Respir Crit Care Med 162: 191–196

    CAS  PubMed  Google Scholar 

  12. de Mendonca A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli M, Takala J, Sprung C, Cantraine F (2000) Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 26: 915–921

    Article  CAS  PubMed  Google Scholar 

  13. Gopal I, Bhonagiri S, Ronco C, Bellomo R (1997) Out of hospital outcome and quality of life in survivors of combined acute multiple organ and renal failure treated with continuous venovenous hemofiltration/hemodiafiltration. Intensive Care Med 23: 766–772

    Article  CAS  PubMed  Google Scholar 

  14. Hou SH, Bushinsky DA, Wish JB, Cohen JJ, Harrington JT (1983) Hospital-acquired renal insufficiency: a prospective study. Am J Med 74: 243–248

    Article  CAS  PubMed  Google Scholar 

  15. Hurel D, Loirat P, Saulnier F, Nicolas F, Brivet F (1997) Quality of life 6 months after intensive care: results of a prospective multicenter study using a generic health status scale and a satisfaction scale. Intensive Care Med 23: 331–337

    Article  CAS  PubMed  Google Scholar 

  16. Joannidis M, Metnitz PG (2005) Epidemiology and natural history of acute renal failure in the ICU. Crit Care Clin 21: 239–249

    Article  PubMed  Google Scholar 

  17. Jones CH, Richardson D, Goutcher E, Newstead CG, Will EJ, Cohen AT, Davison AM (1998) Continuous venovenous high-flux dialysis in multiorgan failure: a 5-year single-center experience. Am J Kidney Dis 31: 227–233

    Article  CAS  PubMed  Google Scholar 

  18. Korkeila M, Ruokonen E, Takala J (2000) Costs of care, long-term prognosis and quality of life in patients requiring renal replacement therapy during intensive care. Intensive Care Med 26: 1824–1831

    Article  CAS  PubMed  Google Scholar 

  19. Lassnigg A, Schmid ER, Hiesmayr M, Falk C, Druml W, Bauer P, Schmidlin D (2008) Impact of minimal increases in serum creatinine on outcome in patients after cardiothoracic surgery: do we have to revise current definitions of acute renal failure? Crit Care Med 36: 1129–1137

    Article  CAS  PubMed  Google Scholar 

  20. Lassnigg A, Schmidlin D, Mouhieddine M, Bachmann LM, Druml W, Bauer P, Hiesmayr M (2004) Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study. J Am Soc Nephrol 15: 1597–1605

    Article  CAS  PubMed  Google Scholar 

  21. Levy EM, Viscoli CM, Horwitz RI (1996) The effect of acute renal failure on mortality. A cohort analysis. JAMA 275: 1489–1494

    Article  CAS  PubMed  Google Scholar 

  22. Lins RL, Elseviers M, Daelemans R, Zachee P, Zachee P, Gheuens E, Lens S, De Broe ME (2000) Prognostic value of a new scoring system for hospital mortality in acute renal failure. Clin Nephrol 53: 10–17

    CAS  PubMed  Google Scholar 

  23. Lins RL, Elseviers MM, Daelemans R (2006) Severity scoring and mortality 1 year after acute renal failure. Nephrol Dial Transplant 21: 1066–1068

    Article  PubMed  Google Scholar 

  24. Loef BG, Epema AH, Smilde TD, Henning RH, Ebels T, Navis G, Stegeman CA (2005) Immediate postoperative renal function deterioration in cardiac surgical patients predicts in-hospital mortality and long-term survival. J Am Soc Nephrol 16: 195–200

    Article  PubMed  Google Scholar 

  25. Lohr JW, McFarlane MJ, Grantham JJ (1988) A clinical index to predict survival in acute renal failure patients requiring dialysis. Am J Kidney Dis 11: 254–259

    CAS  PubMed  Google Scholar 

  26. Luckraz H, Gravenor MB, George R, Taylor S, Williams A, Ashraf S, Argano V, Youhana A (2005) Long and short-term outcomes in patients requiring continuous renal replacement therapy post cardiopulmonary bypass. Eur J Cardiothorac Surg 27: 906–909

    Article  PubMed  Google Scholar 

  27. Martin C, Saran R, Leavey S, Swartz R (2002) Predicting the outcome of renal replacement therapy in severe acute renal failure. ASAIO J 48: 640–644

    Article  PubMed  Google Scholar 

  28. Mattana J, Singhal PC (1993) Prevalence and determinants of acute renal failure following cardiopulmonary resuscitation. Arch Intern Med 153: 235–239

    Article  CAS  PubMed  Google Scholar 

  29. Maynard SE, Whittle J, Chelluri L, Arnold R (2003) Quality of life and dialysis decisions in critically ill patients with acute renal failure. Intensive Care Med 29: 1589–1593

    Article  PubMed  Google Scholar 

  30. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A (2007) Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11: R31

    Article  PubMed  Google Scholar 

  31. Mehta RL, McDonald B, Gabbai FB, Pahl M, Pascual MT, Farkas A, Kaplan RM (2001) A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int 60: 1154–1163

    Article  CAS  PubMed  Google Scholar 

  32. Mehta RL, Pascual MT, Gruta CG, Zhuang S, Chertow GM (2002) Refining predictive models in critically ill patients with acute renal failure. J Am Soc Nephrol 13: 1350–1357

    Article  PubMed  Google Scholar 

  33. Mehta RL, Pascual MT, Soroko S, Savage BR, Himmelfarb J, Ikizler TA, Paganini EP, Chertow GM (2004) Spectrum of acute renal failure in the intensive care unit: the PICARD experience. Kidney Int 66: 1613–1621

    Article  PubMed  Google Scholar 

  34. Metnitz PG, Krenn CG, Steltzer H, Lang T, Ploder J, Lenz K, Le Gall JR, Druml W (2002) Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Crit Care Med 30: 2051–2058

    Article  PubMed  Google Scholar 

  35. Morgera S, Kraft AK, Siebert G, Luft FC, Neumayer HH (2002) Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies. Am J Kidney Dis 40: 275–279

    Article  PubMed  Google Scholar 

  36. Nash K, Hafeez A, Hou S (2002) Hospital-acquired renal insufficiency. Am J Kidney Dis 39: 930–936

    Article  PubMed  Google Scholar 

  37. Newsome BB, Warnock DG, McClellan WM, Herzog CA, Kiefe CI, Eggers PW, Allison JJ (2008) Long-term risk of mortality and end-stage renal disease among the elderly after small increases in serum creatinine level during hospitalization for acute myocardial infarction. Arch Intern Med 168: 609–616

    Article  CAS  PubMed  Google Scholar 

  38. Paganini EP, Halstenberg WK, Goormastic M (1996) Risk modeling in acute renal failure requiring dialysis: the introduction of a new model. Clin Nephrol 46: 206–211

    CAS  PubMed  Google Scholar 

  39. Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359: 7–20

    Article  CAS  PubMed  Google Scholar 

  40. Schafer JH, Maurer A, Jochimsen F, Emde C, Wegscheider K, Arntz HR, Heitz J, Krell-Schroeder B, Distler A (1990) Outcome prediction models on admission in a medical intensive care unit: do they predict individual outcome? Crit Care Med 18: 1111–1118

    Article  CAS  PubMed  Google Scholar 

  41. Schiffl H (2006) Renal recovery from acute tubular necrosis requiring renal replacement therapy: a prospective study in critically ill patients. Nephrol Dial Transplant 21: 1248–1252

    Article  PubMed  Google Scholar 

  42. Silvester W, Bellomo R, Cole L (2001) Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia. Crit Care Med 29: 1910–1915

    Article  CAS  PubMed  Google Scholar 

  43. Tian ZM, Miranda DR (1995) Quality of life after intensive care with the sickness impact profile. Intensive Care Med 21: 422–428

    Article  CAS  PubMed  Google Scholar 

  44. Uchino S, Bellomo R, Kellum JA, Morimatsu H, Morgera S, Schetz MR, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten HM, Ronco C (2007) Patient and kidney survival by dialysis modality in critically ill patients with acute kidney injury. Int J Artif Organs 30: 281–292

    CAS  PubMed  Google Scholar 

  45. Uchino S, Bellomo R, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten H, Ronco C, Kellum JA (2007) Continuous renal replacement therapy: A worldwide practice survey. Intensive Care Med 33: 1563–1570

    Article  PubMed  Google Scholar 

  46. Uehlinger DE, Jakob SM, Ferrari P, Eichelberger M, Huynh-Do U, Marti HP, Mohaupt MG, Vogt B, Rothen HU, Regli B, Takala J, Frey FJ (2005) Comparison of continuous and intermittent renal replacement therapy for acute renal failure. Nephrol Dial Transplant 20: 1630–1637

    Article  PubMed  Google Scholar 

  47. Vinsonneau C, Camus C, Combes A, Costa de Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF (2006) Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 368: 379–385

    Article  PubMed  Google Scholar 

  48. Wald R, Deshpande R, Bell CM, Bargman JM (2006) Survival to discharge among patients treated with continuous renal replacement therapy. Hemodial Int 10: 82–87

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael Joannidis .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Joannidis, M., Metnitz, P.G.H. (2010). Long-Term Outcome of Acute Kidney Injury. In: Jörres, A., Ronco, C., Kellum, J. (eds) Management of Acute Kidney Problems. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69441-0_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69441-0_27

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69413-7

  • Online ISBN: 978-3-540-69441-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics