Abstract
An essential foundation for scientific inquiry in medicine is the quantification of disease severity. Such measures are an imperative in patient care, clinical trials, and epidemiologic research. For clinicians, severity measures serve to establish treatment options, guide the need for ongoing therapy, and to evaluate treatment effectiveness. For clinical drug trials and regulatory authorities, these are critical outcome measures upon which to establish evidence of treatment efficacy. For epidemiologists, they facilitate the study of disease within and between populations. However, for these measures to be useful and effective, they must be accurate, reliable, and capable of reflecting change. Furthermore, their uptake and utilization requires that they also be practical and relevant to their intended application.
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Tan, J.K. (2014). Evaluation of Clinical Severity by Acne Grading and Lesion Counting. In: Zouboulis, C., Katsambas, A., Kligman, A. (eds) Pathogenesis and Treatment of Acne and Rosacea. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69375-8_44
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DOI: https://doi.org/10.1007/978-3-540-69375-8_44
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