Skip to main content

Environmental Factors

The Kobner's Phenomenon

Occupational Vitiligo

  • Chapter
Vitiligo

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Reference

  1. Al’Abadie MS, Senior HJ, Bleehen SS et al (1994) Neuropeptide and neuronal marker studies in vitiligo. Br J Dermatol 131:160–165

    Article  PubMed  Google Scholar 

  2. Asboe-Hansen G (1954) Depigmentation itching. Acta Derm Venereol 34:1–3

    PubMed  CAS  Google Scholar 

  3. Barona MI, Arrunategui A, Falabella R et al (1995) An epi-demiologic case-control study in a population with vitiligo. J Am Acad Dermatol 33:621–625

    Article  PubMed  CAS  Google Scholar 

  4. Beetley F (1951) The provocation of cutaneous disease: Koebner's isomorphic phenomenon. Arch Midds Hosp 1:279–287

    Google Scholar 

  5. Bleehen SS, Hall-Smith P (1970) Brassiere depigmentation: light and electron microscope studies Br J Dermatol 83:157–160

    Article  PubMed  CAS  Google Scholar 

  6. Dupré A, Christol B (1978) Cockade-like vitiligo and linear vitiligo; a variant of Fitzpatrick's trichrome vitiligo. Arch Dermatol Res 262:197–203

    Article  PubMed  Google Scholar 

  7. Eyre RW, Krueger GG (1982) Response to injury of skin involved and uninvolved with psoriasis and its relation to disease activity: Koebner and reverse Koebner reactions. Br J Dermatol 106:153–159

    Article  PubMed  CAS  Google Scholar 

  8. Falabella R, Arunategui A, Barona MI et al (1995) The minigrafting test for vitiligo detection of stable lesions for melanocyte transplantation. J Am Acad Dermatol 32:228–232

    Article  PubMed  CAS  Google Scholar 

  9. Fitzpatrick TB (1971) Vitiligo. Dermatology in general Medicine. Mc Graw Hill, New York, pp 1596–1600

    Google Scholar 

  10. Gauthier Y (1995) The importance of Koebner's phenomenon in the induction of vitiligo vulgaris lesions. Eur J Dermatol 5:704–708

    Google Scholar 

  11. Gauthier Y, Bazeille J-E (1992) Autologous grafting with non cultured melanocytes: a simplified method for treatment of depigmented lesions. J Am Acad Dermatol 26:191–194

    Article  PubMed  CAS  Google Scholar 

  12. Gauthier Y, Cario-André M, Lepreux S et al (2003) Melanocyte detachment after skin friction in non lesional skin of patients with generalized vitiligo. Br J Dermatol 148:95–101

    Article  PubMed  CAS  Google Scholar 

  13. Gauthier Y, Cario-André M, Taieb A (2003) A critical appraisal of vitiligo etiologic theories. Is melanocyte loss a melanocytorrhagy? Pigment Cell Res 16:322–327

    Article  PubMed  Google Scholar 

  14. Gopinathan T (1965) A study of the lesion of vitiligo. Arch Dermatol 91:397–404

    Article  Google Scholar 

  15. Hann SK, Chun WH, Park YK (1997) Clinical charasteris-tics of progressive vitiligo. Int J Dermatol 36:353–355

    Article  PubMed  CAS  Google Scholar 

  16. Hatchome N, Kato T, Tagami H (1990) Therapeutic success of epidermal grafting in generalized vitiligo is limited by the Koebner's phenomenon. J Am Acad Dermatol 22 : 87–91

    Article  PubMed  CAS  Google Scholar 

  17. Kaposi M (1891) Pathologie et traitement des maladies de la peau.Traduction Doyon and Besnier, Masson, France, pp 105–110

    Google Scholar 

  18. Jin Y, Mailloux C, Gowan K et al (2007) NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 356:1216–1225

    Article  PubMed  CAS  Google Scholar 

  19. Koebner H (1877) Zur Aetiologie der Psoriasis. Vrtljscher Dermatol Syphil 1876 8:559–561

    Google Scholar 

  20. Koga M, Tango T (1988) Clinical features and course of type A and type B vitiligo. Br J Dermatol 118:223–228

    Article  PubMed  CAS  Google Scholar 

  21. Lee AY, Kim NH, Choo W-J et al (2005) Less keratinocyte-derived factors related to more keratinocyte apoptosis in depigmented than normally pigmented suction-blistered epidermis may cause passive melanocyte death in vitiligo. J Invest Dermatol 124:976–983

    Article  PubMed  CAS  Google Scholar 

  22. Levaï M (1958) A study of certain contributory factors in the development of vitiligo in South Indian patients. Arch Dermatol 78:364–371

    Article  Google Scholar 

  23. Levaï M (1958) The relation ship of pruritus and local skin conditions to the development of vitiligo. Arch Dermatol 78:372–377

    Article  Google Scholar 

  24. Moellmann G, Klein-Angerer S, Scollary DA et al (1982) Extracellular granular material and degeneration of kerati-nocytes in the normally pigmented epidermis with vitiligo. J Invest Dermatol 79:321–330

    Article  PubMed  CAS  Google Scholar 

  25. Mottaz JH, Thorne G, Zelicson As (1971) Response of the epidermal melanocyte to minor trauma. Arch Dermatol 104:611–618

    Article  PubMed  CAS  Google Scholar 

  26. Mulekar S (2007) Koebner's phenomenon in vitiligo: not always an indication of surgical failure. Arch Dermatol 143:801–802

    Article  PubMed  Google Scholar 

  27. Njoo MD, Das PK, Bos JD et al (1999) Association of the Koebner's phenomenon with disease activity and therapeutic responsiveness in vitiligo vulgaris. Arch Dermatol 135:407–413

    Article  PubMed  CAS  Google Scholar 

  28. Ormsby OS, Montgomery H (1948) Koebner's phenomenon in dermatology: a study and report of some unusual stigmata of this phenomenon. Lea and Febrigerm Philadelphia, pp 306

    Google Scholar 

  29. Ortonne JP (1983) Vitiligo. In: Ortonne JP (ed) Vitiligo and other hypomelanosis of hair and skin. Plenum, New York, pp 163–310

    Chapter  Google Scholar 

  30. Schallreuter KU, Lemke R, Brandt Owesthofen M et al (1994) Vitiligo and other diseases: coexistence or true association? Dermatology 188:268–275

    Article  Google Scholar 

  31. Seif El-Nas RH, El-Hefnawi H (1963) Koebner's phenomenon in dermatology: a study and report of some unusual stigmata of this phenomenon. J Egypt Med Assoc 46:1067–108

    Google Scholar 

  32. Sweet RD (1978) Vitiligo as Koebner's phenomenon. Br J Dermatol 99:223–224

    Article  PubMed  CAS  Google Scholar 

  33. Bajaj A, Gupta S, Chatterjee A (1996) Footwear depigmen-tation. Contact Dermatitis 35:117–118

    Article  PubMed  CAS  Google Scholar 

  34. Bajaj AK, Gupta SC, Chatterjee AK (1990) Contact depig-mentation from free para-tertiary-butylphenol in bindi adhesive. Contact Dermatitis 22:99–102

    Article  PubMed  CAS  Google Scholar 

  35. Bajaj AK, Gupta SC, Chatterjee AK et al (1996) Hair dye depigmentation. Contact Dermatitis 35:56–57

    Article  PubMed  CAS  Google Scholar 

  36. Bajaj AK, Pandey RK, Misra K et al (1998) Contact depig-mentation caused by an azo dye in alta. Contact Dermatitis 38(4):189–193

    Article  PubMed  CAS  Google Scholar 

  37. Bickley LK, Papa CM (1989) Chronic arsenicism with viti-ligo, hyperthyroidism, and cancer. N J Med 86(5):377–380

    PubMed  CAS  Google Scholar 

  38. Bleehen SS, Pathak MA, Hori Y et al (1968) Depigmentation of skin with 4-isopropylcatechol, mercaptoamines and other compounds. J Invest Dermatol 50:103–117

    PubMed  CAS  Google Scholar 

  39. Boissy RE, Nordlund JJ (1995) Biology of vitiligo. In: Arndt KA, LeBoit PE, Robinson JK et al (eds) Cutaneous medicine and surgery: an integrated program in dermatology. WB Saunders, Philadelphia

    Google Scholar 

  40. Boissy RE, Manga P (2004) On the etiology of contact/ occupational vitiligo. Pigment Cell Res 17:208–214

    Article  PubMed  CAS  Google Scholar 

  41. Chumakov NN, Babanov GP, Smirnov AG (1962) Vitiliginoid dermatoses in workers of phenol-formaldehyde resin works. Bull Dermatol 36:3–8

    CAS  Google Scholar 

  42. Cummings MP, Nordlund JJ (1995) Chemical leukoderma: fact or fancy. Am J Contact Dermatitis 6:122–127

    Article  Google Scholar 

  43. Dell'Anna ML, Ottaviani M, Albanesi V et al (2007) Membrane lipid alterations as a possible basis for melano-cyte degeneration in vitiligo. J Invest Dermatol 127(5): 1226–1233

    Article  PubMed  Google Scholar 

  44. Flickinger CW (1976) The benzenediols: catechol, resorci-nol and hydroquinone — a review of the industrial toxicology and current industrial exposure limits. Am Industr Hyg Assoc J 37:596–606

    Article  CAS  Google Scholar 

  45. Gellin GA, Possick PA, Perone VB (1970) Depigmentation from 4-tertiary butyl catechol — an experimental study. J Invest Dermatol 55:190–197

    Article  PubMed  CAS  Google Scholar 

  46. Gellin GA, Maibach HI, Misiaszek MH (1979) Detection of environmental depigmenting substances. Contact Dermatitis 5:201–213

    Article  PubMed  CAS  Google Scholar 

  47. Ghosh S, Mukhopadhyay S (2008) Chemical leukoderma: clinico-etiological study of 864 cases in perspective of developing country. Br J Dermatol 160:40–47

    Article  PubMed  Google Scholar 

  48. Halliwell B, Chirico S (1993) Lipid peroxidation: its mechanism, measurement, and significance. Am J Clin Nutr 57(Suppl 5):715S–725S

    PubMed  CAS  Google Scholar 

  49. Hernandez C, Reddy SG, Le Poole C (2008) Contact leuko-derma after application of a compounded phenol cream. Eur J Dermatol

    Google Scholar 

  50. Ito Y, Jimbow K, Ito S (1987) Depigmentation of black guinea pig skin by topical application of cysteaminylphenol, cysteinylphenol, and related compounds. J Invest Dermatol 88:77–82

    Article  PubMed  CAS  Google Scholar 

  51. James O, Mayes RW, Stevenson CJ (1977) Occupational vitiligo induced by p-tert-butylphenol: a systemic disease? Lancet 2:1217–1219

    Article  PubMed  CAS  Google Scholar 

  52. Jimbow K, Obata H, Pathak MA et al (1974) Mechanism of depigmentation by hydroquinone. J Invest Dermatol 62:436–449

    Article  PubMed  CAS  Google Scholar 

  53. Kahn G (1970) Depigmentation caused by phenolic detergent germicides. Arch Dermatol 102:177–187

    Article  PubMed  CAS  Google Scholar 

  54. Lerner AB (1971) On the etiology of vitiligo and grey hair. Am J Med 51:141–147

    Article  PubMed  CAS  Google Scholar 

  55. Levin CY, Maibach H (2001) Exogenous ochronosis. An update on clinical features, causative agents and treatment options. Clin Dermatol 2:213–217

    Article  CAS  Google Scholar 

  56. Malten KE, Seutter E, Hara I et al (1971) Occupational viti-ligo due to paratertiary butylphenol and homologues. Trans St Johns Hosp Dermatol Soc 57:115–134

    PubMed  CAS  Google Scholar 

  57. Manga P, Sheyn D, Sarangarajan R et al (2005) The microphthalmia-associated transcription factor and tyrosi-nase related-protein 1 play a role in melanocyte response to 4-tertiary butyl phenol. J Invest Dermatol

    Google Scholar 

  58. Manga P, Sheyn D, Yang F et al (2006) A role for tyrosinase related-protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes. Implications for vitiligo. Am J Pathol 169(5): 1652–1662

    Article  PubMed  CAS  Google Scholar 

  59. Mans DR, Lafleur MV, Westmijze EJ et al (1992) Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation. Biochem Pharmacol 43:1761–1768

    Article  PubMed  CAS  Google Scholar 

  60. Marnett LJ (1999) Lipid peroxidation-DNA damage by malondialdehyde. Mutat Res 424(1–2):83–95

    PubMed  CAS  Google Scholar 

  61. McGuire J, Hinders J (1971) Biochemical basis for depig-mentation of skin by phenol germicides. J Invest Dermatol 57:256–261

    Article  PubMed  CAS  Google Scholar 

  62. Monks TJ, Hanzlik RP, Cohen GM et al (1992) Contemporary issues in toxicology. Quinone chemistry and toxicity. Toxicol Appl Pharmacol 112:2–16

    Article  PubMed  CAS  Google Scholar 

  63. Nakagawa Y, Tayama S, Moore G et al (1993) Cytotoxic effects of biphenyl and hydroxybiphenyls on isolated rat hepatocytes. Biochem Pharmacol 45:1959–1965

    Article  PubMed  CAS  Google Scholar 

  64. O'Brien PJ (1991) Molecular mechanisms of quinone cyto-toxicity. Chem Biol Interact 80(1):1–41

    Article  PubMed  Google Scholar 

  65. O'Malley MA, Mathias CG, Priddy M et al (1988) Occupational vitiligo due to unsuspected presence of phenolic antioxidant byproducts in commercial bulk rubber. J Occup Med 30(6):512–516

    Article  PubMed  Google Scholar 

  66. Okmura Y, Shirai T (1962) Vitiliginous lesions occurring among workers in a phenol derivative factory. Jpn J Dermatol 7:617–619

    Google Scholar 

  67. Oliver EA, Schwartz L, Warren LH (1939) Occupational leukoderma. JAMA 113:927–928

    Article  Google Scholar 

  68. Ortonne J-P, Bose SK (1993) Vitiligo: where do we stand? Pigment Cell Res 6:61–72

    Article  PubMed  CAS  Google Scholar 

  69. Pandhi RK, Kumar AS (1985) Contact leukoderma due to ‘Bindi’ and footwear. Dermatologica 170(5):260–262

    Article  PubMed  CAS  Google Scholar 

  70. Powis G (1987) Metabolism and reactions of quinoid anticancer agents. Pharmacol Ther 35(1–2):57–162

    Article  PubMed  CAS  Google Scholar 

  71. Quevedo WC Jr, Fitzpatrick TB, Szabo G et al (1986) Biology of the melanin pigmentary system. In: Fitzpatrick TB, Eisen AZ, Wolff K (eds) Dermatology in general medicine. McGraw-Hill, New York

    Google Scholar 

  72. Rodermund OE, Jorgens H, Muller R et al (1975) [Systemic changes in occupational vitiligo]. Hautarzt 26(6): 312–316

    PubMed  CAS  Google Scholar 

  73. Selvaag E (1996) Chloroquine-induced vitiligo. A case report and review of the literature. Acta Derm Venereol 76:166–167

    PubMed  CAS  Google Scholar 

  74. Shelley W (1974) p-Cresol: cause of ink-induced hair depig-mentation in mice. Br J Dermatol 90:169–174

    Article  PubMed  CAS  Google Scholar 

  75. Sun CC (1987) Allergic contact dermatitis of the face from contact with nickel and ammoniated mercury in spectacle frames and skin-lightening creams. Contact Dermatitis 17:306–309

    Article  PubMed  CAS  Google Scholar 

  76. Takahashi A, Masuda A, Sun M et al (2004) Oxidative stress-induced apoptosis is associated with alterations in mitochon-drial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm). Brain Res Bull 62:497–504

    Article  PubMed  CAS  Google Scholar 

  77. Taylor JS, Maibach HI, Fisher AA et al (1993) Contact leu-koderma associated with the use of hair colors. Cutis 52(5):273–280

    PubMed  CAS  Google Scholar 

  78. Yang F, Sarangarajan R, Le Poole IC et al (2000) The cyto-toxicity and apoptosis induced by 4-tertiary butylphenol in human melanocytes is independent of tyrosinase activity. J Invest Dermatol 114:157–164

    Article  PubMed  CAS  Google Scholar 

  79. Yusof Z, Pratap RC, Nor M et al (1990) Vogt-Koyanagi-Harada syndrome — a case report. Med J Malaysia 45:70–73

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yvon Gauthier .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Gauthier, Y., Benzekri, L., Boissy, R.E. (2010). Environmental Factors. In: Picardo, M., Taïeb, A. (eds) Vitiligo. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69361-1_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69361-1_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69360-4

  • Online ISBN: 978-3-540-69361-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics