Skip to main content
SpringerLink
Log in

Migränemittel

  • Chapter
Arzneiverordnungs-Report 2008

  • 543 Accesses

Zusammenfassung

Triptane dominieren aufgrund ihrer gut belegten therapeutischen Wirksamkeit seit Jahren die Therapie akuter Migräneanfälle. Bei den Migränemitteln gehen mehr als 75% der verordneten Tagesdosen auf das Konto der Triptane. Seit Mitte 2006 stehen preisgünstige Sumatriptangenerika zur Verfügung, Wahrscheinlich stellt aus diesem Grund Sumatriptan wieder das gemessen in Tagesdosen mit Abstand am häufigsten verordnete Triptan dar. Allein an diesen Wirkstoff gehen fast 40% aller verordneten Triptantagesdosen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Arzneimittelkommission der deutschen Ärzteschaft (1995): Kontraindikation bei Sumatriptan beachten. Dtsch Ärztebl 92: A-1546–1547.

    Google Scholar 

  • Becker A, Buck W, Vögtle-Junkert U (1988): Analgesie und Antiemese — Therapieziele in der Migränebehandlung. Med Welt 39: 473–476.

    Google Scholar 

  • Becker A, Berner G, Leuschner F, Vögtle-Junkert U (1992): Pharmakokinetische Aspekte zur Kombination von Metoclopramid und Paracetamol. Arzneim-Forschg 42: 552–555.

    CAS  Google Scholar 

  • Bomhof M, Paz J, Legg N, Allen C, Vandormael K, Patel K (1999): Comparison of rizatriptan 10 mg vs naratriptan 2.5 mg in migraine. Eur Neurol 42: 173–179.

    Article  CAS  PubMed  Google Scholar 

  • Brandes JL, Kudrow DB, Rothrock JF, Rupnow MF, Fairclough DL, Greenberg SJ. (2006) Assessing the ability of topiramate to improve the daily activities of patients with migraine. Mayo Clin Proc 81: 1311–1319.

    Article  CAS  PubMed  Google Scholar 

  • Chronicle E, Mulleners W (2004) Anticonvulsant drugs for migraine prophlaxis. Cochrane Database of Systematic Reviews 2004, Issue 3. Art. No. CD003226. DOI: 10.100

    Google Scholar 

  • Deutsche Gesellschaft für Neurologie: Therapie der Migräneattacke und Migräneprophylaxe. Leitlinien für Diagnostik und Therapie in der Neurologie; 3. überarbeitete Auflage 2005, ISBN3-13-132413-9; Georg Thieme Verlag Stuttgart.

    Google Scholar 

  • Dichgans J, Diener HC, Gerber WD, Verspohl EJ, Kukiolka H, Kluck M (1984): Analgetika-induzierter Dauerkopfschmerz. Dtsch Med Wochenschr 109: 369–373.

    Article  CAS  PubMed  Google Scholar 

  • Diener HC, Bussone G, Van Oene J, Lahaye M, Schwalen S, Goadsby P; TOPMATMIG-201(TOP-CHROME) Study Group (2007). Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study Cephalalgia 27: 814–823.

    Article  PubMed  Google Scholar 

  • Diener HC, Katsarava Z (2001): Medication overuse headache. Curr Med Res Opin 17Suppl 1: sl7–s21.

    Google Scholar 

  • Ferrari MD, Roon KI, Lipton RB, Goadsby PJ (2001): Oral triptans (serotonin 5-HT1B1D agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet 358: 1668–1675.

    Article  CAS  PubMed  Google Scholar 

  • Gruffyd-Jones K, Kies B, Middleton A, Mulder LJ, Rosjo O, Millson DS (2001): Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study. Eur J Neurol 8: 237–245.

    Article  CAS  PubMed  Google Scholar 

  • Katsarava Z, Fritsche G, Muessig M, Diener HC, Limmroth V (2001): Clinical features of withdrawal headache following overuse of triptans and otherheadache drugs. Neurology 57: 1694–1698.

    CAS  PubMed  Google Scholar 

  • Kaube H, May A, Diener HC, Pfaffenrath V (1994): Sumatriptan. Brit Med J 308: 1573–1574.

    CAS  PubMed  Google Scholar 

  • Krobot KJ, Steinberg HW, Pfaffenrath V (1999): Migraine prescription density and recommendations. Results of the PCAOM study. Cephalalgia 19: 511–519.

    Article  CAS  PubMed  Google Scholar 

  • Limmroth V, Kazawara Z, Fritsche G, Diener HC (1999): Headache after frequent use of serotonin agonists zolmitriptan and naratriptan. Lancet 353: 378.

    Article  CAS  PubMed  Google Scholar 

  • Sandrini G, Farkkila M, Burgess G, Forster E, Haughie S, Eletriptan Steering Committee (2002): Eletriptan vs sumatriptan: a double-blind, placebo-controlled, multiple migraine attack study. Neurology 59: 1210–1217.

    CAS  PubMed  Google Scholar 

  • Silberstein SD, Lipton RB, Dodick DW, Freitag FG, Ramadan N, Mathew N, Brandes JL, Bigal M, Saper J, Ascher S, Jordan DM, Greenberg SJ, Hulihan J (2007) Topiramate Chronic Migraine Study Group. Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial. Headache 47: 170–180.

    Article  PubMed  Google Scholar 

  • Soldin OP, Tonning JM; Obstetric-Fetal Pharmacology Research Unit Network (2008): Serotonin syndrome associated with triptan monotherapy. N Engl J Med 358: 2185–2186.

    Article  CAS  PubMed  Google Scholar 

  • Spierings EL, Gomez-Mancilla B, Grosz DE, Rowland CR, Whaley FS, Jirgens KJ (2001): Oral almotriptan vs oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparison. Arch Neurol 58: 944–950.

    Article  CAS  PubMed  Google Scholar 

  • Steiner TJ, Diener HC, MacGregor EA, Schoenen J, Muirheads N, Sikes CR (2003): Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine. Cephalalgia 23: 942–952.

    Article  CAS  PubMed  Google Scholar 

  • Tfelt-Hansen P, Herny P, Mulder LJ, Scheldewaert RG, Schoenen J, Chazot G (1995): The effectiveness of combined oral lysine acetylsalicylate and metoclopramide compared with oral sumatriptan for migraine. Lancet 346: 923–926.

    Article  CAS  PubMed  Google Scholar 

  • Tfelt-Hansen P, Olesen J, Aebelholt-Krabbe A, Melgaard B, Veilis B (1980): A double blind study of metoclopramide in the treatment of migraine attacks. J Neurol Neurosurg Psychiatry 43: 369–371.

    Article  CAS  PubMed  Google Scholar 

  • Wenzel RG, Schwarz K, Padiyara RS (2006) Topiramate for migraine prevention. Pharmacotherapy 26: 375–387.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ludwigstraße. 37, 79104, Freiburg

    Dr. rer. nat. Judith Günther

Authors
  1. Dr. rer. nat. Judith Günther
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg

    Ulrich Schwabe

  2. Die Gesundheitskasse, AOK Schleswig-Holstein, Edisonstraße 70, 24145, Kiel

    Dieter Paffrath

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer Medizin Verlag Heidelberg

About this chapter

Cite this chapter

Günther, J. (2008). Migränemittel. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2008. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69219-5_33

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69219-5_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69218-8

  • Online ISBN: 978-3-540-69219-5

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation