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Mechanisms of Transcriptional Regulation

  • Chapter
Genomic Imprinting

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 25))

Abstract

The phenomenon of genomic imprinting, whatever its biological functions and evolutionary origins may be, ultimately manifests itself in the monoallelic expression of certain genes. The assumption has been, therefore, that the transcriptional regulatory systems of imprinted genes would directly or indirectly represent the principal focus of the imprinting process. As this chapter will discuss, however, our perceptions of gene regulation mechanisms are currently undergoing a radical re-evaluation and some of the emerging concepts may prove to be of importance to our understanding of how genomic imprinting functions.

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Authors and Affiliations

  1. Department of Animal Development & Genetics, Uppsala University, Norbyvägen 18A, S-752 36, Uppsala, Sweden

    Gary C. Franklin

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  1. Gary C. Franklin
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Editors and Affiliations

  1. Dept. of Animal Development and Genetics, University of Uppsala, Norbyvägen 18 A, 75236, Uppsala, Sweden

    Rolf Ohlsson

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© 1999 Springer-Verlag Berlin Heidelberg

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Franklin, G.C. (1999). Mechanisms of Transcriptional Regulation. In: Ohlsson, R. (eds) Genomic Imprinting. Results and Problems in Cell Differentiation, vol 25. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69111-2_8

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  • DOI: https://doi.org/10.1007/978-3-540-69111-2_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21956-0

  • Online ISBN: 978-3-540-69111-2

  • eBook Packages: Springer Book Archive

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