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Dielectric Characterization of Biological Tissues: Constraints Related to Ex Vivo Measurements

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Sensors

Part of the book series: Lecture Notes Electrical Engineering ((LNEE,volume 21))

Abstract

Electrical Impedance Spectroscopy (EIS) has been previously reported as a technique for non-invasive assessment of electromagnetic tissue properties. In the frequency range up to 10 MHz, current conduction through tissue is mainly determined by the tissue structure, i.e. the extra- and intra-cellular compartments and the insulating cell membranes. Therefore, changes in the extra- and intra-cellular fluid volumes are reflected in the impedance spectra. E.I.S. systems include electrodes for the measurement of the impedance. Different electrodes configurations are used to measure bioelectric phenomenon for both macroscopic and microscopic approaches. Electrodes for macroscopic characterization are used for bio impedance measurement of a great biological tissue sample or organ. In this paper, we briefly review and discuss metrological aspects relating to electrical characterization of biological tissues based on the difficulty to compare between different author’s results. Experimental results obtained on different kinds of biological tissues (blood and bone) are presented and discussed as examples according to the influencing constraints specific to their physiological nature.

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Author information

Authors and Affiliations

  1. L.I.E.N., BP 239 Faculty of Sciences and Techniques, Nancy University, 54506 Vandoeuvre, les Nancy

    Mustapha Nadi

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  1. Mustapha Nadi
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Editors and Affiliations

  1. School of Engineering and Advanced Technology (SEAT), Massey University (Turitea Campus), Palmerston North, New Zealand

    S.C. Mukhopadhyay

  2. Department of Engineering Science, National Cheng-Kung University, Tainan, Taiwan

    R.Y.M. Huang

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Nadi, M. (2008). Dielectric Characterization of Biological Tissues: Constraints Related to Ex Vivo Measurements. In: Mukhopadhyay, S., Huang, R. (eds) Sensors. Lecture Notes Electrical Engineering, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69033-7_5

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  • DOI: https://doi.org/10.1007/978-3-540-69033-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69030-6

  • Online ISBN: 978-3-540-69033-7

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