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Pseudotumor Orbitae

  • Chapter
Radiotherapy for Non-Malignant Disorders

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Pseudotumor orbitae is a rare and uncommon disease including idiopathic benign inflammatory alterations with sudden onset of exophthalmus, reduced eye motility, swelling of soft tissue and heavy pain together with a tumor formation, which may even simulate a neoplastic process. In some situations, its masquerade as a neoplasm is so deceptive as to defy diagnosis until orbitotomy. In any case, a bioptic verification, if possible and assessable, is recommended. A localized inflammatory process with lymphocytic infiltration is often described histologically. However the pathologists sometimes report great difficulties in separating the lesion from a malignant non-Hodgkin’s lymphoma of the orbit. Because morphologic criteria alone may sometimes not allow distinguishing between benign and malignant disease, immunohistochemical examinations are necessary. Diagnosis has to be done using clinical examinations, characteristic CT or MR findings, intensive histologic analysis including immunohistochemic investigations.

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Author information

Authors and Affiliations

  1. Service de Radiothérapie, Hôpital Neuchâtelois, Rue de Chasserai 20, 2300, La Chaux-de-Fonds, Switzerland

    Markus Notter MD

  2. Comprehensive Cancer Center of Wake Forest University, Medical Center Boulevard, Winston-Salem, NC, 27157, USA

    Kathryn M. Greven MD (Professor of Radiation Oncology)

Authors
  1. Markus Notter MD
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  2. Kathryn M. Greven MD
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Editor information

Editors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, Postfach 10 22 43, 45117, Essen, Germany

    Michael Heinrich Seegenschmiedt MD (Professor) (Professor)

  2. Strahlenklinik Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany

    Hans-Bruno Makoski MD (Professor) (Professor)

  3. Department of Radiation Biology, St. Bartolomew’s Medical College, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott MD (Professor) (Professor)

  4. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

  5. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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© 2008 Springer-Verlag Berlin Heidelberg

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Notter, M., Greven, K.M. (2008). Pseudotumor Orbitae. In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_27

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  • DOI: https://doi.org/10.1007/978-3-540-68943-0_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-62550-6

  • Online ISBN: 978-3-540-68943-0

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