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Langerhans′ Cell Histiocytosis (LCH)

  • Chapter
Radiotherapy for Non-Malignant Disorders

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Langerhans’ cell histiocytosis (LCH) is a rare semimalignant disease in which an uncontrolled proliferation of Langerhans’ cells involves one or more body systems or tissues, leading to different clinical manifestations. Langerhans’ cell histiocytosis nowadays includes diseases previously designated as histiocytosis X, eosinophilic granuloma, Hand-Schüller-Christian syndrome or Abt-Letterer-Siwe disease. Langerhans’ cell histiocytosis usually is considered to be a typical disease of children; nevertheless, many adults are newly diagnosed, and the disease course in children can continue during their adult life. Primary isolated pulmonary Langerhans’ cell histiocytosis, especially in adults, seems to represent a special form of disease [24, 109, 116] requiring specialized (non-radiotherapeutic) treatment and is not addressed in this book chapter.

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Authors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, 45117, Essen, Germany

    Thomas Olschewski MD (Professor) & Michael Heinrich Seegenschmiedt MD (Professor)

  2. Department of Radiation Therapy and Radiation Oncology, Franziskus Hospital, Kiskerstraße 26, 33615, Bielefeld, Germany

    Oliver Micke MD PD

Authors
  1. Thomas Olschewski MD
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  2. Michael Heinrich Seegenschmiedt MD
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  3. Oliver Micke MD PD
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Editor information

Editors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, Postfach 10 22 43, 45117, Essen, Germany

    Michael Heinrich Seegenschmiedt MD (Professor) (Professor)

  2. Strahlenklinik Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany

    Hans-Bruno Makoski MD (Professor) (Professor)

  3. Department of Radiation Biology, St. Bartolomew’s Medical College, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott MD (Professor) (Professor)

  4. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

  5. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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© 2008 Springer-Verlag Berlin Heidelberg

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Olschewski, T., Seegenschmiedt, M.H., Micke, O. (2008). Langerhans′ Cell Histiocytosis (LCH). In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_22

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  • DOI: https://doi.org/10.1007/978-3-540-68943-0_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-62550-6

  • Online ISBN: 978-3-540-68943-0

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