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Pigmented Villonodular Synovitis (PVNS)

  • Chapter
Radiotherapy for Non-Malignant Disorders

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

The pigmented villonodular synovitis (PVNS) is a very uncommon non-malignant, but proliferative disease, eventually with locally aggressive behavior, that can affect synovial-lined joints, bursae and tendon sheaths. PVNS is well characterized by a hyperplastic synovium of the affected joint, frequent and large effusions and para-articular bony erosions. The first physician ever to describe the lesion was the French surgeon Chassaignac in 1852 (1804–1879), but he overstated its biologic potential in referring to it as a “cancer of the tendon sheath.” It took almost 100 years for the first correct clinical description of PVNS as a distinct disease entity to be given by Jaffe and coworkers in 1941 [20]. They proposed the actual name and described the typical clinical and histological findings.

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Authors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, 45117, Essen, Germany

    Ralf Oppenkowski MD (Professor) & Michael Heinrich Seegenschmiedt MD (Professor)

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  1. Ralf Oppenkowski MD
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  2. Michael Heinrich Seegenschmiedt MD
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Editors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, Postfach 10 22 43, 45117, Essen, Germany

    Michael Heinrich Seegenschmiedt MD (Professor) (Professor)

  2. Strahlenklinik Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany

    Hans-Bruno Makoski MD (Professor) (Professor)

  3. Department of Radiation Biology, St. Bartolomew’s Medical College, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott MD (Professor) (Professor)

  4. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

  5. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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© 2008 Springer-Verlag Berlin Heidelberg

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Oppenkowski, R., Seegenschmiedt, M.H. (2008). Pigmented Villonodular Synovitis (PVNS). In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_21

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  • DOI: https://doi.org/10.1007/978-3-540-68943-0_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-62550-6

  • Online ISBN: 978-3-540-68943-0

  • eBook Packages: MedicineMedicine (R0)

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