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Modelling and Imaging Electrophysiology and Contraction of the Heart

  • Conference paper
Advances in Medical Engineering

Part of the book series: Springer Proceedings in Physics ((SPPHY,volume 114))

Abstract

A computer model of the human heart is presented, that starts with the electrophysiology of single myocardial cells including all relevant ion channels, spans the de- and repolarization of the heart including the generation of the Electrocardiogram (ECG) and ends with the contraction of the heart that can be measured using 4D Magnetic Resonance Imaging (MRI). The model can be used to better understand physiology and pathophysiology of the heart, to improve diagnostics of infarction and arrhythmia and to enable quantitative therapy planning. It can also be used as a regularization tool to gain better solutions of the ill-posed inverse problem of ECG. Movies of the evolution of electrophysiology of the heart can be reconstructed from Body Surface Potential Maps (BSPM) and MRI, leading to a new non-invasive medical imaging technique.

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Author information

Authors and Affiliations

  1. Institute of Biomedical Engineering, Universität Karlsruhe (TH), Kaiserstr. 12, 76131, Karlsruhe, Germany

    Olaf Dössel, Dima Farina, Matthias Mohr, Matthias Reumann, Gunnar Seemann & Daniel L. Weiss

Authors
  1. Olaf Dössel
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  2. Dima Farina
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  3. Matthias Mohr
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  4. Matthias Reumann
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  5. Gunnar Seemann
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  6. Daniel L. Weiss
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Editor information

Editors and Affiliations

  1. Institute of Medical Engineering, University of Luebeck, Ratzeburger Allee 160, D-23538, Luebeck, Germany

    Thorsten M. Buzug

  2. Department of Mathematics and Technology, RheinAhrCampus Remagen, Germany

    Dietrich Holz , Jens Bongartz , Matthias Kohl-Bareis  & Ulrich Hartmann , ,  & 

  3. Central Institute for Electronics, Research Centre Juelich, Germany

    Simone Weber

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© 2007 Springer-Verlag Berlin Heidelberg

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Dössel, O., Farina, D., Mohr, M., Reumann, M., Seemann, G., Weiss, D.L. (2007). Modelling and Imaging Electrophysiology and Contraction of the Heart. In: Buzug, T.M., Holz, D., Bongartz, J., Kohl-Bareis, M., Hartmann, U., Weber, S. (eds) Advances in Medical Engineering. Springer Proceedings in Physics, vol 114. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68764-1_1

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  • DOI: https://doi.org/10.1007/978-3-540-68764-1_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68763-4

  • Online ISBN: 978-3-540-68764-1

  • eBook Packages: EngineeringEngineering (R0)

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