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Cutaneous T-Cell Lymphomas and Rare T-Cell Non-Hodgkin Lymphomas

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Pediatric Lymphomas

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References

  • Agnarsson B, Kadin ME. Ki-1-positive large-cell lymphoma: A morphologic and immunologic study of 19 cases. Am J Surg Pathol 1988; 12:264–274.

    PubMed  CAS  Google Scholar 

  • Agnarsson BA, Vonderheid EC, Kadin ME. Cutaneous T-cell lymphoma with suppressor/cytotoxic (CD8) phenotype: Identification of rapidly progressive and chronic subtypes. J Am Acad Dermatol. 1990;22:569–577.

    PubMed  CAS  Google Scholar 

  • Assaf C, Mummel M, Steinhoff M, Geilen CC, Orawa H, Stain H, Orfanos CE. Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications. Blood 2005;105:503–510.

    Article  PubMed  CAS  Google Scholar 

  • Bekkenk M, Geelen FAMJ, van Voorst Vader PC, et al. Primary and secondary cutaneous CD30-positive lymphoproliferative disorders: long term follow-up data of 219 patients and guidelines for diagnosis and treatment. A report from the Dutch Cutaneous Lymphoma Group. Blood 2000;95:3653–3661.

    PubMed  CAS  Google Scholar 

  • Belhadj K, Reyes F et al. Hepatosplenic gamma-delta T-cell lymphoma is a rare clinicopathologic entity with poor outcome: a report on a series of 21 patients. Blood 2003;102: 4261–4269.

    Article  PubMed  CAS  Google Scholar 

  • Beljaards RC, Meijer CJLM, Ber-H2, Scheffer E, et al. Prognostic significance of CD30 (Ki-1/Ber-H2) expression in primary cutaneous large-cell lymphomas of T-cell origin. A clinicopathologic and immunohistochemical study in 20 patients. Am J Pathol 1989;135:1169–1178.

    PubMed  CAS  Google Scholar 

  • Berti E, Tomasini D, Vermeer MH, Meijer CJLM, Alessi E, Willemze R. Primary cutaneous CD8-positive epidermotropic cytotoxic T-cell lymphoma: a distinct clinicopathologic entity with an aggressive clinical behaviour. Am J Pathol 1999;155: 483–492.

    PubMed  CAS  Google Scholar 

  • Bonzheim I, Geissinger E, Roth S, Zettla A, Marx S, Rosenwald A, Mueller-Hermelink HK, Ruediger T. Anaplastic large cell lymphomas lack expresion of T-cell receptor molecules or molecules of proximal T-cell receptor signaling. Blood 2004; 104:3358–3360.

    Article  PubMed  CAS  Google Scholar 

  • Bunn PA, Lamberg SI. Report of the Committee on Staging and Classification of Cutaenous T-cell lymphomas. Cancer Treatment Reports 1979; 63:725–728.

    PubMed  Google Scholar 

  • Burg G, Kempf W, Kazakov DV, et al. Pyogenic lymphoma of the skin: a peculiar variant of primary cutaneous neutrophil-rich lymphoma. Clinicopathologic study of four cases and review of the literature. Br J Dermatol 2003; 148:1–7.

    Article  Google Scholar 

  • Burg G, Dummer R, Wilhelm M, et al. A subcutaneous delta-positive T-cell lymphoma that produces interferon gamma. N Engl J Med 1991;325:1078–1081.

    Article  PubMed  CAS  Google Scholar 

  • Cabanillas F, Armitage J, Pugh WC, Weisenburger D, Duvic M. Lymphomatoid papulosis: a T-cell dyscrasia with propensity to transform to malignant lymphoma. Ann Intern Med 1995;122:210–217.

    PubMed  CAS  Google Scholar 

  • Chott A, Vonderheid EC, Miao NN, Balk SP, Kadin ME. Detection of the same dominant T cell clone in multiple regressing skin lesions and associated T cell lymphomas of patients with lymphomatoid papulosis. J Invest Dermatol 1996;106:696–700.

    Article  PubMed  CAS  Google Scholar 

  • Cooke CB, Krenacs M, Stetler-Stevenson M, et al. Hepatosplenic gamma/delta T-cell lymphoma: a distinict clinical pathologic entity of gamma/delta T-cell origin. Blood 1996;88:4265–4274.

    PubMed  CAS  Google Scholar 

  • Davis TM, Morton CC, Miller-Cassman R, Balk SP, Kadin ME. Hodgkin’s disease, lymphomatoid papulosis and cutaneous T-cell lymphoma derived from a common T-cell clone. N Engl J Med 1992;326:1115–1122.

    Article  PubMed  CAS  Google Scholar 

  • De Bruin PC, Beljaards RC, van Heerde P, et al. Differences in clinical behaviour and immunophenotype between primary cutaneous and primary nodal anaplastic large cell lymphoma of T-or null cell phenotype. Histopathol 1993;23:127–135.

    Google Scholar 

  • De Couteau JF, Butmarc JR, Kinney MC, Kadin ME. The t(2;5) chromosomal translocation is not a common feature of primary cutaneous CD30+ lymphoproliferative disorders: comparison with anaplastic large cell lymphoma of nodal origin. Blood 1996;87:3437–3441.

    Google Scholar 

  • Dereure O, Levi E, Vonderheid EC, Kadin ME. Infrequent mutations of Fas but not p53 or Bax in early mycosis fungoides. A possible mechanism for accumulation of malignant T-lymphocytes in the skin. J Invest Derm 2002; 118:949–956.

    Article  PubMed  CAS  Google Scholar 

  • Diamandidou E, Cohen PR, Kurzrock R. Mycosis fungoides and Sezary syndrome. Blood 1996; 88:2385–2409.

    PubMed  CAS  Google Scholar 

  • Diamandidou E, Colome-Grimmer M, Fayad L, Duvic M, Kurzrock R. Transformation of mycosis fungoides/Sézary syndrome: clinical characteristics and prognosis. Blood. 1998;92:1150–1159.

    PubMed  CAS  Google Scholar 

  • Domm J, Thompson M, et al. Allogeneic bone marrow transplantation for chemotherapy-refractory gammadelta hepatosplenic T-cell lymphoma. J Pediatr Hematol Oncol 2005; 27(11): 607–610.

    Article  PubMed  Google Scholar 

  • Dummer R, Kempf W, Hess Schmid M, et al. Therapy of cutaneous lymphoma — current practice and future developments. Onkologie 2003; 26:366–372.

    Article  PubMed  CAS  Google Scholar 

  • Duvic M, Cather JC. Emerging new therapies for cutaneous T-cell lymphoma. Dermatol Clin 2000;18:147–156.

    PubMed  CAS  Google Scholar 

  • Edelson R, Berger C, Gasparro F, et al. Treatment of cutaneous T-cell lymphoma by extracorporeal photochemotherapy. N Eng J Med 1987; 316:297–303.

    Article  CAS  Google Scholar 

  • El Shabrawi-Caelen L, Kerl H, Cerroni L. Lymphomatoid papulosis. Reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C. Arch Dermatol 2004;140:441–447.

    Article  PubMed  Google Scholar 

  • Farcet J, Galulard P. Marolleau J, et al. Hepatosplenic T-cell lymphoma: Sinusal/sinusoidal localization of malignant cells expressing the T-cell receptor γδ. Blood 1990;75:2213–2219.

    PubMed  CAS  Google Scholar 

  • Fink-Puches R, Chott A, et al. The spectrum of cutaneous lymphomas in patients less than 20 years of age. Pediatr Dermatol 2004; 21(5): 525–33.

    Article  PubMed  Google Scholar 

  • Flaig MJ, Cerroni L, Schuhmann K, et al. Follicular mycosis fungoides. A histopathologic analysis of nine cases. J Cutan Pathol 2001; 28:525–30.

    Article  PubMed  CAS  Google Scholar 

  • Gaulard P, Zafrani ES, Mavier P, et al. Peripheral T-cell lymphoma presenting as predominant liver disease: report of 3 cases. Hepatology 1986; 6:864–868.

    PubMed  CAS  Google Scholar 

  • Gaulard P, Bourquelot P, Kanavaros P, et al. Expression of alpha/beta and gamma/delta T-cell receptors in 57 cases of peripheral T-cell lymphomas: identification of a subset of gamma/delta T-cell lymphomas. Am J Pathol 1990;137:617–628.

    PubMed  CAS  Google Scholar 

  • Gellrich S, Wernicke M, Wilks A, et al. The cell infiltrate in lymphomatoid papulosis comprises a mixture of polyclonal large atypical cells (CD30-positive) and smaller monoclonal T-cells (CD30-negative). J Invest Dermatol 2004; 122:859–61.

    Article  PubMed  CAS  Google Scholar 

  • Gniadecki R, Lukowsky A, Rossen K, Madsen HO, Thomsen K, Wulf HC. Bone marrow precursor of extranodal T-cell lymphoma. Blood 2003; 102:3797–99.

    Article  PubMed  CAS  Google Scholar 

  • Gonzalez CL, Medeiros LJ, Braziiel RM, Jaffe ES. T-cell lymphoma involving subcutaneous tissue. A clinicopathologic entity commonly associated with hemophagocytic syndrome. Am J Surg Pathol 1991; 15:17–27.

    PubMed  CAS  Google Scholar 

  • Groves FD, Linet MS, Travis LB, Devesa SS. Cancer Surveillance Series: Non-Hodgkin’s Lymphoma Incidence by histologic subtype in the United States from 1978 through 1995. J Natl Cancer Inst 2000; 92:1240–1251

    Article  PubMed  CAS  Google Scholar 

  • Hoefnagel J, Dijkman R, et al. Distinct types of primary cutaneous large B cell lymphoma identified by gene expression profiling. Blood 2005; 105: 3671–3678

    Article  PubMed  CAS  Google Scholar 

  • Hoque SR, Child FJ, Whittaker SJ, et al. Subcutaneous panniculitis-like T-cell lymphoma: a clinicopathological, immunophenotypic and molecular analysis of six patients. Br J Dermatol 2003; 148:516–525.

    Article  PubMed  CAS  Google Scholar 

  • Jones GW, Kacinski BM, Wilson LD, et al. Total skin electron radiation in the management of mycosis fungoides: Consensus of the European Organization for Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Project Group. J Am Acad Dermatol 2002; 47:364–370.

    Article  PubMed  Google Scholar 

  • Kadin ME, Kamoun M, Lamberg J. Erythrophagocytic T gamma lymphoma. A clinicopathologic entity resembling malignant histiocytosis. N Engl J Med 1981; 304:648–653.

    Article  PubMed  CAS  Google Scholar 

  • Kadin M, Nasu K, Sako D, Said J, Vonderheid E. Lymphomatoid papulosis. A cutaneous proliferation of activated helper T cells expressing Hodgkin’s Disease associated antigens. Am J Pathol 1985; 119:315–25

    PubMed  CAS  Google Scholar 

  • Kahwash S, Qualman S. Cutaneous lymphoblastic lymphoma in children: a report of six cases with precursor B cell lineage. Pediatr Dev Pathol 2002; 5(1): 45–53.

    Article  PubMed  Google Scholar 

  • Karenko L, Kahkonen M, Hyytinen ER, Lindlof M, Ranki A. Notable losses at specific regions of chromosomes 10q and 13q in the Sezary syndrome detected by comparative genomic hybridization. J Invest Dermatol 1999; 112:392–395.

    Article  PubMed  CAS  Google Scholar 

  • Kaudewitz P, Stein H, Dallenbach F, et al. Primary and secondary cutaneous Ki-1+ (CD30+) anaplastic large cell lymphomas. Morphologic, immunohistologic, and clinical characteristics. Am J Pathol 1989; 135:359–367.

    PubMed  CAS  Google Scholar 

  • Kaye FJ, Bunn PA, Steinberg SM, et al. A randomized trial comparing combination electron beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides. N Eng J Med 1989; 321:784–790.

    Article  Google Scholar 

  • Kim YH, Liu HL, Mraz-Gernhard S, Varghese A, Hoppe RT. Long-term outcome of 525 patients with mycosis fungoides and Sezary syndrome: clinical prognostic factors and risk for disease progression. Arch Dermatol 2003;139:857–866.

    Article  PubMed  Google Scholar 

  • Kummer JA, Vermeer MH, Dukers DF, Meijer CJLM, Willemze R. Most primary cutaneous CD30-positive lymphoproliferative disorders have a CD4-positive cytotoxic T-cell phenotype. J Invest Dermatol 1997; 109:636–40.

    Article  PubMed  CAS  Google Scholar 

  • Kupper T, Fuhlbrigge R. Immune surveillance in the skin: mechanisms and clinical consequences. Nature Reviews, Immunology 2004; 4(3): 211–22

    Article  CAS  Google Scholar 

  • Lin P, Jones D, et al. Precursor B-cell lymphoblastic lymphoma: a predominantly extranodal tumor with low propensity for leukemic involvement. Am J Surg Pathol 2002;24: 1480–90.

    Google Scholar 

  • Liu HL, Hoppe RT, Kohler S, Harvell JD, Reddy S, Kim YH. CD30+ cutaneous lymphoproliferative disorders: The Stanford experience in lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. J Am Acad Dermatol 2003; 49:1049–1058.

    Article  PubMed  Google Scholar 

  • Lorincz AL. Cutaneous T-cell lymphoma (mycosis fungoides). Lancet 1996; 347:871–876.

    Article  PubMed  CAS  Google Scholar 

  • Lundin J, Hagberg H, Repp R, et al. Phase II study of alemtuzumab (anti-CD52 monoclonal antibody, CAMPATH-1H) in patients with advanced mycosis fungoides. Blood 2003;101:4267–4272.

    Article  PubMed  CAS  Google Scholar 

  • Macon WR, Levy NB, Kurtin PJ, et al. Hepatosplenic alphabeta T-cell lymphomas: report of 14 cases and comparison with hepatosplenic gammadelta T-cell lymphomas. Am J Surg Pathol 2001; 25:285–296.

    Article  PubMed  CAS  Google Scholar 

  • Mao X, Lillington D, Scarisbrick JJ, et al. Molecular cytogenetic analysis of cutaneous T-cell lymphomas: identification of common genetic alterations in Sezary syndrome and mycosis fungoides. Br J Dermatol 2002; 147:464–475.

    Article  PubMed  CAS  Google Scholar 

  • Mao X, Lillington DM, Czepulkowski B, Russell-Jones R, Young BD, Whittaker S. Molecular cytogenetic characterization of Sezary syndrome. Genes Chromosomes Cancer 2003a; 36:250–260.

    Article  PubMed  CAS  Google Scholar 

  • Mao X, Orchard G, Lillington DM, Russell-Jones R, Young BD, Whittaker SJ. Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas. Blood 2003b; 15(101):1513–1519.

    Article  CAS  Google Scholar 

  • Marzano AV, Berti E, Paulli M, et al. Cytophagic histiocytic panniculitis and subcutaneous panniculities-like T-cell lymphoma: report of 7 cases. Arch Dermatol 2000; 136:889–896.

    Article  PubMed  CAS  Google Scholar 

  • Mori M, Mannuelli C, Pimpinelli N, et al. CD30-CD30L interaction in primary cutaneous CD30+ T-cell lymphomas: A clue to the pathophysiology of clinical regression. Blood 1999; 94: 3077–83.

    PubMed  CAS  Google Scholar 

  • Murphy S, Fairclough D. Non-Hodgkin’s lymphomas of childhood: an analysis of the histology, staging, and response to treatment of 338 cases at a single institution. J Clin Oncol 1989; 7(2): 186–93.

    PubMed  CAS  Google Scholar 

  • Nickoloff BJ. Light-microscopic assessment of 100 patients with patch/plaque-stage mycosis fungoides. Am J Dermatopathol 1988; 10:469–77.

    Article  PubMed  CAS  Google Scholar 

  • Nijsten T, Curiel-Lewandrowski C, Kadin ME. Lymphomatoid papulosis in children. A retrospective cohort study of 35 cases. Arch Dermatol 2004;140:306–312.

    Article  PubMed  Google Scholar 

  • Olsen EA, Bunn PA. Interferon in the treatment of cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 1995;9:1089–1097.

    PubMed  CAS  Google Scholar 

  • Paulli M, Berti E, Rosso R, et al. CD30/Ki-1 positive lymphoproliferative disorders of the skin: clinicopathologic correlation and and statistical analysis of 86 cases. J Clin Oncol 1995; 13:1343–1354.

    PubMed  CAS  Google Scholar 

  • Peters K, Knoll JHM, Kadin ME. Cytogenetic findings in regressing skin lesions of lymphomatoid papulosis. Cancer Genetics Cytogenetics 1995; 80:13–16.

    Article  CAS  Google Scholar 

  • Ruebben A, Kempf W, Kadin ME, Zimmermann DR, Burg G. Multilineage progression of genetically unstable tumor subclones in cutaneous T-cell lymphoma revealed by microdissection and allelotyping. Exp Dermatol 2004;13:472.

    Article  CAS  Google Scholar 

  • Russell-Jones R. Extracorporeal photopheresis in cutaneous T-cell lymphoma. Inconsistent data underline the need for randomized studies. Br J Dermatol 2000; 142:16–21

    Article  PubMed  CAS  Google Scholar 

  • Salhany KE, Macon WR, Choi JK, et al. Subcutaneous panniculitis-like T-cell lymphoma: clinicopathologic, immunophenotypic, and genotypic analysis of alpha/beta and gamma/delta subtypes. Am J Surg Pathol 1998;22:881–893.

    Article  PubMed  CAS  Google Scholar 

  • Santucci M, Pimpinelli N, Massi D, et al. Cytotoxic/natural killer cell cutaneous lymphomas. Report of EORTC Cutaneous Lymphoma Task Force Workshop. Cancer 2003;97:610–627.

    Article  PubMed  Google Scholar 

  • Sausville EA, Eddy JL, Makuch RW, et al. Histopathological staging at initial diagnosis of mycosis fungoidies and Sezary syndrome: Definition of three distinctive prognostic groups. Ann Intern Med 1988, 109:372–382.

    PubMed  CAS  Google Scholar 

  • Scheffer E, Meijer CJLM, van Vloten WA, Willemze R. A histologic study of lymph nodes from patients with the Sezary syndrome. Cancer 1986;57:2375–2380.

    Article  PubMed  CAS  Google Scholar 

  • Sentis HJ, Willemze, Scheffer E. Histopathologic studies in Sezary syndrome and erythrodermic mycosis fungoides: a comparison with benign forms of erythroderma. J Am Acad Dermatol 1986;15:1217–1226.

    PubMed  CAS  Google Scholar 

  • Sibaud V, Beylot-Barry M, Thiebaut R, et al. Bone marrow histopathologic and molecular staging in epidermotropic T-cell lymphomas. Am J Clin Pathol 2003;119:414–423.

    Article  PubMed  Google Scholar 

  • Smoller BR, Santucci M, Wood GS, Whittaker SJ. Histopathology and genetics of cutaneous T-cell lymphoma. Hematol Oncol Clin North Am 2003;17:1277–1311.

    Article  PubMed  Google Scholar 

  • Thangavelu M, Finn WG, Yelavarthi KK, et al. Recurring structural chromosome abnormalities in peripheral blood lymphocytes of patients with mycosis fungoides/Sezary syndrome. Blood 1997;89:3371–3377.

    PubMed  CAS  Google Scholar 

  • Toonstra J, Henquet CJM, van Weelden H, van der Putte SCJ, van Vloten WA. Actinic reticuloid: a clinical, photobiologic, histopathologic and follow-up study of 16 cases. J Am Acad Dermatol 1989;21:205–214

    PubMed  CAS  Google Scholar 

  • Trotter MJ, Whittaker SJ, Orchard GE, Smith NP. Cutaneous histopathology of Sezary syndrome: a study of 41 cases with a proven circulating T-cell clone. J Cutan Pathol 1997;24:286–291.

    Article  PubMed  CAS  Google Scholar 

  • Van Doorn R, Scheffer E, Willemze R. Follicular mycosis fungoides: a distinct disease entity with or without associated follicular mucinosis. Arch Dermatol 2001;138:191–198.

    Article  Google Scholar 

  • Van Doorn R, Van Haselen CW, van Voorst VPC et al. Mycosis fungoides: disease evolution and prognosis in 309 Dutch patients. Arch Dermatol 2000:136:504–510.

    Article  PubMed  Google Scholar 

  • Varga FJ, Vonderheid EC, Olbricht SM, Kadin ME. Immunohistochemical distinction of lymphomatoid papulosis and pityriasis lichenoides et variolaformis acuta (PLEVA). Am Pathol 1990;136: 979–987.

    CAS  Google Scholar 

  • Vermeer MH, Geelen FAMJ, Kummer JA, et al. Expression of cytotoxic proteins by neoplastic T-cells in mycosis fungoides is associated with progression from plaque stage to tumor stage disease. Am J Pathol 1999;154:1203–1210

    PubMed  CAS  Google Scholar 

  • Vonderheid EC, Sajjadian A, Kadin ME. Methotrexate is effective therapy for lymphomatoid papulosis and other primary cutaneous CD30-positive lymphoproliferative disorders. J Am Acad Dermatol 1996;34:470–480.

    Article  PubMed  CAS  Google Scholar 

  • Vonderheid EC, Bernengo MG, Burg G, et al. Update on erythrodermic cutaneous T-cell lymphoma: report of the International Society for Cutaneous Lymphomas. J Am Acad Dermatol 2002;46:95–106.

    Article  PubMed  Google Scholar 

  • Wain EM, Orchard GE, Whittaker SJ, Spittle M, Russell-Jones R. Outcome in 34 patients with juvenile-onset mycosis fungoides: a clinical, immunophenotypic, and molecular study. Cancer 2003;98:2282–2290.

    Article  PubMed  Google Scholar 

  • Wang CC, Tien JF, Lin MR, et al. Consistent presence of isochromosome 7q in hepatosplenic T gamma/delta lymphoma: a new cytogenetic-clinicopathologic entity. Genes Chromosomes Cancer 1995;12:161–164.

    PubMed  CAS  Google Scholar 

  • Wang HH, Lach L, Kadin ME. Epidemiology of lymphomatoid papulosis. Cancer 1992; 70:2951–7.

    Article  PubMed  CAS  Google Scholar 

  • Wang HH, Myers T, Lach LJ, Hsieh CC, Kadin ME. Increased risk of lymphoid and non-lymphoid malignancies in patients with lymphomatoid papulosis. Cancer 1999; 86:1240–5.

    Article  PubMed  CAS  Google Scholar 

  • Weenig RH, Ng CS, Perniciaro C. Subcutaneous panniculitis-like T-cell lymphoma. Am J Dermatopathol 2001;23:206–215.

    Article  PubMed  CAS  Google Scholar 

  • Weiss L, Wood G, Trela M, Warnke RA, Sklar J. Clonal T-cell populations in lymphomatoid papulosis. N Engl J Med 1986;315:475–479.

    Article  PubMed  CAS  Google Scholar 

  • Whittaker SJ, Marsden JR, Spittle M, Russell Jones R. Joint British Association of Dermatologists and U.K. Cutaneous Lymphoma Group guidelines for the management of primary cutaneous T-cell lymphomas. Br J Dermatol 2003;149:1095–1107.

    Article  PubMed  CAS  Google Scholar 

  • Whittam LR, Calonje E, Orchard G, Fraser-Andrews EA, Woolford A, Russell-Jones R. CD8-positive juvenile onset mycosis fungoides: an immunohistochemical and genotypic analysis of six cases. Br J Dermatol 2000;143:1199–1204.

    Article  PubMed  CAS  Google Scholar 

  • Wieselthier JS, Koh HK. Sézary syndrome: diagnosis, prognosis and critical review of treatment options. J Am Acad Dermatol 1990;22:381–401

    Article  PubMed  CAS  Google Scholar 

  • Willemze R, Beljaards RC. Spectrum of primary cutaneous CD30+ lymphoproliferative disorders. A proposal for classification and guidelines for management and treatment. J Am Acad Dermatol 1993; 28:973–980

    PubMed  CAS  Google Scholar 

  • Willemze R, Kerl H, Sterry W, et al. EORTC classification for primary cutaneous lymphomas. A Proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer (EORTC). Blood 1997; 90:354–371.

    PubMed  CAS  Google Scholar 

  • Willemze R, Jaffe ES, Burg G, et al. WHO-EORTC classification of cutaneous lymphoma. Blood 2005;105(10): 3768–85.

    Article  PubMed  CAS  Google Scholar 

  • Willers J, Dummer R, Kempf W, Kundig T, Burg G, Kadin ME. Proliferation of CD30+ T helper 2 cells can be inhibited by CD30 receptor cross-linking with recombinant CD30 ligand. Clin Cancer Res 2003; 9:2744–54.

    PubMed  CAS  Google Scholar 

  • Yawalkar N, Ferenczi K, Jones DA, Yamanaka K, Suh K-Y, Sadat S, Kupper TS. Profound loss of T-cell receptor repertoire complexity in cutaneous T-cell lymphoma. Blood 2003; 102:4059–4066.

    Article  PubMed  CAS  Google Scholar 

  • Zackheim HS, Amin S, Kadhani-Sabet M, McMillan A. Prognosis in cutaneous T-cell lymphoma by skin stage: long term survival in 489 patients. J Am Acad Dermatol 1999;40:418–25.

    Article  PubMed  CAS  Google Scholar 

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Kadin, M.E. (2007). Cutaneous T-Cell Lymphomas and Rare T-Cell Non-Hodgkin Lymphomas. In: Weinstein, H.J., Hudson, M.M., Link, M.P. (eds) Pediatric Lymphomas. Pediatric Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68753-5_10

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