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Schon zu Urzeiten gebrauchten menschen natürliche und artifizielle Mittel zur Anxiolyse und als Hypnotika. So ist bekannt, dass schon die Sumerer vor mehr als 7000 Jahren Opium benutzten, wenn vielleicht auch mehr als Analgetikum oder für kultische Handlungen. Die ersten schriftlichen Rezepte des Bierbrauens sind von 3500 v. Chr. auf einem ägyptischen Papyrus überliefert, während die entsprechenden Reinheitsgebote schon aus babylonischer Zeit bekannt sind. Es kann davon ausgegangen werden, dass Bier zwar im Wesentlichen als ein Nahrungsmittel galt, es aber auch wegen seiner anxiolytischen und hypnotischen Eigenschaften geschätzt wurde.

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Lüddens, H., Wiedemann, K. (2008). Anxiolytika und Hypnotika. In: Holsboer, F., Gründer, G., Benkert, O. (eds) Handbuch der Psychopharmakotherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68748-1_31

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