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The Phycodnaviridae: The Story of How Tiny Giants Rule the World

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Book cover Lesser Known Large dsDNA Viruses

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 328))

The family Phycodnaviridae encompasses a diverse and rapidly expanding collection of large icosahedral, dsDNA viruses that infect algae. These lytic and lysogenic viruses have genomes ranging from 160 to 560 kb. The family consists of six genera based initially on host range and supported by sequence comparisons. The family is monophyletic with branches for each genus, but the phycodnaviruses have evolutionary roots that connect them with several other families of large DNA viruses, referred to as the nucleocytoplasmic large DNA viruses (NCLDV). The phycodnaviruses have diverse genome structures, some with large regions of noncoding sequence and others with regions of ssDNA. The genomes of members in three genera in the Phycodnaviridae have been sequenced. The genome analyses have revealed more than 1000 unique genes, with only 14 homologous genes in common among the three genera of phycodnaviruses sequenced to date. Thus, their gene diversity far exceeds the number of so-called core genes. Not much is known about the replication of these viruses, but the consequences of these infections on phytoplankton have global affects, including influencing geochemical cycling and weather patterns.

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  1. Bigelow Laboratory for Ocean Sciences, 180 McKown Point, P.O. Box 475, West Boothbay Harbor, ME, 04575-0475, USA

    W. H. Wilson

  2. Plymouth Marine Laboratory, Prospect Place, The Hoe, Plymouth PL1 3DH, UK

    M. J. Allen

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Correspondence to W. H. Wilson .

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  1. Department of Plant Pathology and Nebraska Center for Virology, University of Nebraska, Lincoln, NE, 68583-0722, USA

    James L. Van Etten

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© 2009 Springer-Verlag Berlin Heidelberg

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Wilson, W.H., Van Etten, J.L., Allen, M.J. (2009). The Phycodnaviridae: The Story of How Tiny Giants Rule the World. In: Van Etten, J.L. (eds) Lesser Known Large dsDNA Viruses. Current Topics in Microbiology and Immunology, vol 328. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68618-7_1

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