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High-Field fMRI

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fMRI

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Abstract

In recent years, functional magnetic resonance imaging (fMRI) has become a widely used approach for neuroscience. However, this method has the potential to be improved with regard to both spatial and temporal resolution. The blood-oxygenation level-dependent contrast (BOLD) represents signal changes in T2 or T2* weighted images. These sequences are presumed to be well suited to high magnetic field strength, as fMRI sequences benefit from higher signal-to-noise ratio (SNR) and higher signal in BOLD contrast images (Vaughan et al. 2001). However, their sensitivity to susceptibility also causes problems, e.g. in-plane dephas-ing and signal dropouts near tissue-air boundaries.

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References

  • Alvarez-Linera J (2008) 3T MRI: advances in brain imaging. Eur J Radiol 67(3):415–426

    Article  PubMed  Google Scholar 

  • Duong TQ, Yacoub E et al (2003) Microvascular BOLD contribution at 4 and 7 T in the human brain: gradient-echo and spin-echo fMRI with suppression of blood effects. Magn Reson Med 49(6):1019–1027

    Article  PubMed  Google Scholar 

  • Gizewski ER, de Greiff A et al (2007) fMRI at 7 T: whole-brain coverage and signal advantages even infratentorially? Neuroimage 37(3):761–768

    Article  PubMed  Google Scholar 

  • Goodyear BG, Douglas EA (2008) Minimum detectable change in motor and prefrontal cortex activity over repeated sessions using 3T functional MRI and a block design. J Magn Reson Imaging 28(5):1055–1060

    Article  PubMed  Google Scholar 

  • Gowland PA, Bowtell R (2007) Theoretical optimization of multiecho fMRI data acquisition. Phys Med Biol 52(7): 1801–1813

    Article  CAS  PubMed  Google Scholar 

  • Heid O (1997) Robust EPI phase correction. In: Proceedings of the ISMRM, Vancouver

    Google Scholar 

  • Hoffmann MB, Stadler J et al (2009) Retinotopic mapping of the human visual cortex at a magnetic field strength of 7T. Clin Neurophysiol 120(1):108–116

    Article  PubMed  Google Scholar 

  • Ladd ME (2007) High-field-strength magnetic resonance: potential and limits. Top Magn Reson Imaging 18(2): 139–152

    Article  PubMed  Google Scholar 

  • Mirrashed F, Sharp JC et al (2004) High-resolution imaging at 3T and 7T with multiring local volume coils. MAGMA 16(4): 167–173

    Article  PubMed  Google Scholar 

  • Norris DG (2003) High field human imaging. J Magn Reson Imaging 18(5):519–529

    Article  PubMed  Google Scholar 

  • Okada T, Yamada H et al (2005) Magnetic field strength increase yields significantly greater contrast-to-noise ratio increase: measured using BOLD contrast in the primary visual area. Acad Radiol 12(2):142–147

    Article  PubMed  Google Scholar 

  • Pfeuffer J, Adriany G et al (2002a) Perfusion-based high-resolution functional imaging in the human brain at 7 Tesla. Magn Reson Med 47(5):903–911

    Article  Google Scholar 

  • Pfeuffer J, Van de Moortele PF et al (2002b) Correction of physiologically induced global off-resonance effects in dynamic echo-planar and spiral functional imaging. Magn Reson Med 47(2):344–353

    Article  Google Scholar 

  • Pfeuffer J, Van de Moortele PF et al (2002c) Zoomed functional imaging in the human brain at 7 Tesla with simultaneous high spatial and high temporal resolution. Neuroimage 17(1): 272–282

    Article  Google Scholar 

  • Poser BA, Versluis MJ et al (2006) BOLD contrast sensitivity enhancement and artifact reduction with multiecho EPI: parallel-acquired inhomogeneity-desensitized fMRI. Magn Reson Med 55(6):1227–1235

    Article  PubMed  Google Scholar 

  • Preibisch C, Wallenhorst T et al (2008) Comparison of parallel acquisition techniques generalized autocalibrating partially parallel acquisitions (GRAPPA) and modified sensitivity encoding (mSENSE) in functional MRI (fMRI) at 3T. J Magn Reson Imaging 27(3):590–598

    Article  PubMed  Google Scholar 

  • Scheef L, Landsberg MW et al (2007) [Methodological aspects of functional neuroimaging at high field strength: a critical review.]. Rofo 179(9):925–931

    CAS  PubMed  Google Scholar 

  • Shimada Y, Kochiyama T et al (2008) System stability of a 3T-MRI during continuous EPI scan. Nippon Hoshasen Gijutsu Gakkai Zasshi 64(12):1504–1512

    PubMed  Google Scholar 

  • Triantafyllou C, Hoge RD et al (2005) Comparison of physiological noise at 1.5 T, 3 T and 7 T and optimization of fMRI acquisition parameters. Neuroimage 26(1): 243–250

    Article  CAS  PubMed  Google Scholar 

  • Triantafyllou C, Hoge RD et al (2006) Effect of spatial smoothing on physiological noise in high-resolution fMRI. Neuroimage 32(2):551–557

    Article  PubMed  Google Scholar 

  • Vaughan JT, Garwood M et al (2001) 7T vs. 4T: RF power, homogeneity, and signal-to-noise comparison in head images. Magn Reson Med 46(1):24–30

    Article  CAS  PubMed  Google Scholar 

  • Walter M, Stadler J et al (2008) High resolution fMRI of subcortical regions during visual erotic stimulation at 7 T. MAGMA 21(1–2):103–111

    Article  PubMed  Google Scholar 

  • Wiggins GC, Potthast A et al (2005) Eight-channel phased array coil and detunable TEM volume coil for 7 T brain imaging. Magn Reson Med 54(1):235–240

    Article  CAS  PubMed  Google Scholar 

  • Yacoub E, Duong TQ et al (2003) Spin-echo fMRI in humans using high spatial resolutions and high magnetic fields. Magn Reson Med 49(4):655–664

    Article  PubMed  Google Scholar 

  • Yacoub E, Hu X (2001) Detection of the early decrease in fMRI signal in the motor area. Magn Reson Med 45(2): 184–190

    Article  CAS  PubMed  Google Scholar 

  • Yacoub E, Shmuel A et al (2001) Imaging brain function in humans at 7 Tesla. Magn Reson Med 45(4):588–594

    Article  CAS  PubMed  Google Scholar 

  • Zou KH, Greve DN et al (2005) Reproducibility of functional MR imaging: preliminary results of prospective multi-institutional study performed by Biomedical Informatics Research Network. Radiology 237(3): 781–789

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstrasse 55, Essen, 45127, Germany

    Elke R. Gizewski

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  1. Elke R. Gizewski
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Correspondence to Elke R. Gizewski .

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Editors and Affiliations

  1. Institute of Neuroradiology Neurocenter, University Hospital of Schleswig-Holstein, Schittenhelmstr. 10, Kiel, 24105, Germany

    Stephan Ulmer

  2. Institute of Neuroradiology Neurocenter, University Hospital of Schleswig-Holstein, Schittenhelm Str. 10, 24105, Kiel, Germany

    Olav Jansen

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© 2010 Springer-Verlag Berlin Heidelberg

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Gizewski, E.R. (2010). High-Field fMRI. In: Ulmer, S., Jansen, O. (eds) fMRI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68132-8_5

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  • DOI: https://doi.org/10.1007/978-3-540-68132-8_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-68131-1

  • Online ISBN: 978-3-540-68132-8

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