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Bacterial Endophthalmitis Following Cataract Surgery

  • Chapter
Book cover The Role of Biofilms in Device-Related Infections

Part of the book series: Springer Series on Biofilms ((BIOFILMS,volume 3))

Abstract

Cataracts are the most common cause of blindness in the world and cataract surgery is one of the most common surgical procedures performed. During surgery the opacified crystalline lens is removed and replaced with a lens implant. Bacterial infection of the internal eye (bacterial endophthalmitis) following cataract surgery appears to have increased since the 1990s. The infection is the result of inoculation of the patient’s bacterial flora into the eye during surgery. Under normal circumstances a small inoculum of bacteria can be cleared from the eye without clinical infection. In this chapter, we discuss many factors that can predispose a patient to developing a clinical endophthalmitis, including those related to the lens implant and host response. There is evidence to suggest that the intraocular lens may provide a niche where bacteria are protected from the host mechanisms that normally clear bacteria from the eye.

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Authors and Affiliations

  1. Department of Surgery (Ophthalmology) and Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, NH, USA

    M. E. Zegans & C. M. Toutain-Kidd

  2. Schepens Eye Research Institute, Harvard Medical School, Boston, MA, USA

    M. S. Gilmore

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  1. M. E. Zegans
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  2. C. M. Toutain-Kidd
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  3. M. S. Gilmore
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Correspondence to M. S. Gilmore .

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Editors and Affiliations

  1. Department of Biomedical Sciences, University of Maryland School of Medicine, 655 W. Baltimore Street, Baltimore, MD, 21201, USA

    Mark Shirtliff

  2. Department of Biological Sciences, Northern Arizona University, Box 5640, Flagstaff, AZ, 86011, USA

    Jeff G. Leid

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Zegans, M.E., Toutain-Kidd, C.M., Gilmore, M.S. (2008). Bacterial Endophthalmitis Following Cataract Surgery. In: Shirtliff, M., Leid, J.G. (eds) The Role of Biofilms in Device-Related Infections. Springer Series on Biofilms, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68119-9_8

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