Fine-needle Aspiration Cytology of the Thyroid

  • Anne E. Busseniers
  • Susan A. Silver


Thyroid Nodule Papillary Carcinoma Follicular Adenoma Follicular Neoplasm Follicular Epithelial Cell 
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  1. 1.
    Al-Hureibi KA, Al-Hureibi AA, Abdulmughni YA, et al (2003) The diagnostic value of fine needle aspiration cytology in thyroid swellings in a university hospital, Yemen. Saudi Med J 24:499–503PubMedGoogle Scholar
  2. 2.
    Arda IS, Yildirim S, Demirhan B, et al (2001) Fine needle aspiration biopsy of thyroid nodules. Arch Dis Child 85:313–317PubMedCrossRefGoogle Scholar
  3. 3.
    Atkinson BF (1993) Fine needle aspiration of the thyroid. Monogr Pathol 35:166–199PubMedGoogle Scholar
  4. 4.
    Atkinson BF, Ernst CS, LiVolsi VA (1986) Cytologic diagnoses of follicular tumors of the thyroid. Diagn Cytopathol 2:1–3PubMedGoogle Scholar
  5. 5.
    Aversa S, Pivano G, Vergano R, et al (1999) The accuracy of the fine-needle aspiration biopsy in 1250 thyroid nodules. Acta Otorhinolaryngol Ital 19:260–264PubMedGoogle Scholar
  6. 6.
    Bahar G, Braslavsky D, Shpitzer T, et al (2003) The cytological and clinical value of thyroid “follicular lesions.” Am J Otolaryngol 24:217–220PubMedCrossRefGoogle Scholar
  7. 7.
    Bakhos R, Selvaggi SM, De Jong S, et al (2000) Fine-needle aspiration of the thyroid: rate and causes of cytohistopathologic discordance. Diagn Cytopathol 23:233–237PubMedCrossRefGoogle Scholar
  8. 8.
    Bakshi NA, Mansoor I, Jones BA (2003) Analysis of inconclusive fine-needle aspiration of thyroid follicular lesions. Endocr Pathol 14:167–175PubMedCrossRefGoogle Scholar
  9. 9.
    Baloch ZW, LiVolsi VA (2000) Warthin-like papillary carcinoma of the thyroid. Arch Pathol Lab Med 124:1192–1195PubMedGoogle Scholar
  10. 10.
    Baloch ZW, LiVolsi VA (2004) Fine-needle aspiration of thyroid nodules: past, present and future. Endocr Pract 10:234–241PubMedGoogle Scholar
  11. 11.
    Baloch ZW, Sack MJ, Yu GH, et al (1998) Fine-needle aspiration of thyroid: and institutional experience. Thyroid 8:565–569PubMedGoogle Scholar
  12. 12.
    Baloch ZW, Fleisher S, LiVolsi VA, et al (2002) Diagnosis of “follicular neoplasm”: a gray zone in thyroid fine-needle aspiration cytology. Diagn Cytopathol 26:41–44PubMedCrossRefGoogle Scholar
  13. 13.
    Baloch Z, LiVolsi VA, Jain R, et al (2003) Role of repeat fine-needle aspiration biopsy (FNAB) in the management of thyroid nodules. Diagn Cytopathol 29:203–206PubMedCrossRefGoogle Scholar
  14. 14.
    Blansfield JA, Sack MJ, Kukora JS (2002) Recent experience with preoperative fine-needle aspiration biopsy of thyroid nodules in a community hospital. Arch Surg. 137:818–821PubMedCrossRefGoogle Scholar
  15. 15.
    Block, Dailey GE, Robb JA (1983) Thyroid nodules indeterminate by needle biopsy. Am J Surg 146:72–78PubMedCrossRefGoogle Scholar
  16. 16.
    Bose S, Kapila K, Verma K (1992) Medullary carcinoma of the thyroid: a cytological, immunocytochemical, and ultrastructural study. Diagn Cytopathol 8:28–32PubMedGoogle Scholar
  17. 17.
    Brander A, Viikinkoski P, Nickels J, et al (1991) Thyroid gland: US screening in a random adult population. Radiology 181:683–687PubMedGoogle Scholar
  18. 18.
    Busseniers AE (1993) The “unsatisfactory” thyroid aspirate: facts and fiction. Acta Cytol 37:808Google Scholar
  19. 19.
    Busseniers AE (1996) Superficial fine needle aspiration. Introduction and technique. In: Erozan H, Bonfiglio TA (eds) Fine needle aspiration of subcutaneous organs and masses. Lippincott-Raven, Philadelphia, pp 1–6Google Scholar
  20. 20.
    Busseniers AE (2005) FNA of the thyroid: experience of one dedicated cytopathologist. Program and Abstract Book of the 87th Annual Meeting of the The Endocrine Society, San Diego, CA, 2005, p 319Google Scholar
  21. 21.
    Busseniers AE, Oertel YC (1993) “Cellular adenomatoid nodules” of the thyroid: review of 219 fine-needle aspirates. Diagn Cytopathol 9:581–588PubMedGoogle Scholar
  22. 22.
    Cap J, Ryska A, Rehorkova, et al (2000) Sensitivity and specificity of the fine needle aspiration biopsy of the thyroid: clinical point of view. Clin Endocrinol 51:509–515CrossRefGoogle Scholar
  23. 23.
    Carcangiu ML, Zampi G, Rosai J (1984) Poorly differentiated (insular) thyroid carcinoma: a reinterpretation of Langhans’Wuchernde struma. Am J Surg Pathol 8:655–668PubMedCrossRefGoogle Scholar
  24. 24.
    Carcangiu ML, Zampi G, Pupi A, et al (1985a) Papillary carcinoma of the thyroid: a clinicopathologic study of 241 cases treated at the University of Florence, Italy. Cancer 55:805–828PubMedCrossRefGoogle Scholar
  25. 25.
    Carcangiu ML, Steeper T, Zampi G, et al (1985b) Anaplastic thyroid carcinoma: a study of 70 cases. Am J Clin Pathol 83:135–158PubMedGoogle Scholar
  26. 26.
    Carpi A, Nicolini A, Casara D, et al (2003) Nonpalpable thyroid carcinoma: clinical controversies on preoperative selection. Am J Clin Oncol 26:232–235PubMedCrossRefGoogle Scholar
  27. 27.
    Caruso D, Mazzaferri EL (1991) Fine needle aspiration biopsy in the management of thyroid nodules. Endocrinologist 1:194–202CrossRefGoogle Scholar
  28. 28.
    Caruso G, Tabarri B, Lucchi I, et al (1990) Fine needle aspiration cytology in a case of diffuse sclerosing carcinoma of the thyroid. Acta Cytol 34:352–354PubMedGoogle Scholar
  29. 29.
    Chehade JM, Silverberg AB, Kim J, et al (2001) Role of repeated fine-needle aspiration of thyroid nodules with benign cytologic features. Endocr Pract 7:237–243PubMedGoogle Scholar
  30. 30.
    Chen H, Nicol TL, Rosenthal DL, Udelsman R (1997) The role of fine-needle aspiration in the evaluation of thyroid nodules. In: Norton JA (ed) Problems in general surgery: surgery of the thyroid gland. Lippincott-Raven, New York, pp 1–13Google Scholar
  31. 31.
    Chen H, Nicol TL, Zeiger MA, et al (1998) Hurthle cell neoplasms of the thyroid: are there factors predictive of malignancy? Ann Surg 227:542–546PubMedCrossRefGoogle Scholar
  32. 32.
    Chen H, Dudley NE, Westra WH, et al (2003) Utilization of fine-needle aspiration in patients undergoing thyroidectomy at two academic centers across the Atlantic. World J Surg 27:208–211PubMedGoogle Scholar
  33. 33.
    Chow LS, Gharib H, Goellner JR, et al (2001) Nondiagnostic thyroid fine-needle aspiration cytology: management dilemmas. Thyroid 11:1147–1151PubMedCrossRefGoogle Scholar
  34. 34.
    Christensen SB, Eriscsson UB, Janzon L, et al (1984) The prevalence of thyroid disorders in a middle-aged female population, with special reference to the solitary thyroid nodule. Acta Chir Scand 150:13–19PubMedGoogle Scholar
  35. 35.
    Damiani S, Dina R, Eusebi V (1994) Cytologic grading of aggressive and nonaggressive variants of papillary thyroid carcinoma. Am J Clin Pathol 101:651–655PubMedGoogle Scholar
  36. 36.
    Das A, Gupta SK, Banerjee AK, et al (1992) Atypical cytologic features of medullary carcinoma of the thyroid: a review of 12 cases. Acta Cytol 36:137–141PubMedGoogle Scholar
  37. 37.
    Das DK, Gupta SK, Franci IM, et al (1993) Fine-needle aspiration cytology diagnosis of non-Hodgkin lymphoma of thyroid: a report of four cases. Diagn Cytopathol 9:639–645PubMedGoogle Scholar
  38. 38.
    Das DK, Mallik MK, Sharma P, et al (2004) Papillary thyroid carcinoma and its variants in fine needle aspiration smears. A cytomorphologic study with special reference to tall cell variant. Acta Cytol 48:325–336PubMedGoogle Scholar
  39. 39.
    de los Santos ET, Keyhani-Rofagha S, Cunningham JJ, et al (1990) Cystic thyroid nodules: the dilemma of malignant lesions. Arch Intern Med 150:1422–1427PubMedCrossRefGoogle Scholar
  40. 40.
    DeMay RM (1996) In the art and science of cytopathology. ASCP Press, Chicago, p 711Google Scholar
  41. 41.
    De Vos tot Nederveen Cappel RJ, Bouvy ND, Bonjer HJ, et al (2001) Fine needle aspiration cytology of thyroid nodules: how accurate is it and what are the causes of discrepancy cases? Cytopathology 12:399–405PubMedCrossRefGoogle Scholar
  42. 42.
    Dwarakanathan AA, Staren ED, D’Amore MJ, et al (1993) Importance of repeat fine-needle biopsy in the management of thyroid nodules. Am J Surg 166:350–352PubMedCrossRefGoogle Scholar
  43. 43.
    Elliott RHE Jr, Frantz VK (1960) Metastatic carcinoma masquerading as primary thyroid cancer: a report of author’s 14 cases. Am Surg 151:551–561Google Scholar
  44. 44.
    Erdogan MF, Kamel N, Aras D, et al (1998) Value of reaspirations in benign nodular thyroid disease. Thyroid 8:1087–1090PubMedGoogle Scholar
  45. 45.
    Flint A, Lloyd RV (1990) Hurthle-cell neoplasms of the thyroid gland. Pathol Annu 25:37–52PubMedGoogle Scholar
  46. 46.
    Frable MA, Frable WJ (1980) Fine needle aspiration biopsy of the thyroid: histopathologic and clinical correlations. Prog Surg Pathol 1:105–118Google Scholar
  47. 47.
    Fulciniti F, Benincasa G, Vetrani A, et al (2001) Follicular variant of papillary carcinoma: cytologic findings on FNAB samples: experience with 16 cases. Diagn Cytopathol 25:86–93PubMedCrossRefGoogle Scholar
  48. 48.
    Gagneten CB, Roccatagliata G, Lowenstein A, et al (1987) The role of fine needle aspiration biopsy cytology in the evaluation of the clinically solitary thyroid nodule. Acta Cytol 31:713–716Google Scholar
  49. 49.
    Gandolfi PP, Frisina A, Raffa M, et al (2004) The incidence of thyroid carcinoma in multinodular goiter: retrospective analysis. Acta Biomed Ateneo Parmense 75:114–117Google Scholar
  50. 50.
    Garcia Solano J, Gimenez Bascunana A, Sola Perez J, et al (1997) Fine-needle aspiration of subacute granulomatous thyroiditis (de Quervain’s thyroiditis): a clinico-cytologic review of 36 cases. Diagn Cytopathol 16:214–220PubMedCrossRefGoogle Scholar
  51. 51.
    Gharib H (1994) Fine needle aspiration biopsy of thyroid nodules: advantages, limitations, and effect. Mayo Clin Proc 69:44–49PubMedGoogle Scholar
  52. 52.
    Gharib H, Goellner JR (1993) Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med 118:282–289PubMedGoogle Scholar
  53. 53.
    Gharib H, Goellner JR, Zinsmeister AR, et al (1984) Fine-needle aspiration biopsy of the thyroid: the problem of suspicious cytologic findings. Ann Intern Med 101:25–28PubMedGoogle Scholar
  54. 54.
    Gharib H, Goellner JR, Johnson DA (1993) Fine-needle aspiration cytology of the thyroid: a 12-year experience with 11,000 biopsies. Clin Lab Med 13:699–709PubMedGoogle Scholar
  55. 55.
    Giard RW, Hermans J (2000) Use and accuracy of fine-needle aspiration cytology in histologically proven thyroid carcinoma: an audit using a national pathology database. Cancer 90:330–334PubMedCrossRefGoogle Scholar
  56. 56.
    Guarda LA, Baskin HJ (1987) Inflammatory and lymphoid lesions of the thyroid gland: cytomorphology by fine-needle aspiration. Am J Clin Pathol 87:14–22PubMedGoogle Scholar
  57. 57.
    Guarda LA, Peterson CE, Hall W, et al (1991) Anaplastic thyroid carcinoma. Cytomorphology and clinical implications of fine-needle aspiration. Diagn Cytopathol 7:63–67PubMedGoogle Scholar
  58. 58.
    Hamburger JI, Hamburger SW (1986) Fine needle biopsy of thyroid nodules: avoiding the pitfalls. NY State J Med 86:241–249Google Scholar
  59. 59.
    Hamburger B, Gharib H, Melton LF III, et al (1982) Fine needle aspiration biopsy of thyroid nodules: impact on thyroid practice and cost of care. Am J Med 73:381–384CrossRefGoogle Scholar
  60. 60.
    Hamburger JL, Miller JM, Kini SR, et al (1983) Lymphoma of the thyroid. Ann Intern Med 99:685–693PubMedGoogle Scholar
  61. 61.
    Hammer M, Wortsman J, Folse R (1982) Cancer in cystic lesions of the thyroid. Arch Surg 117:1020–1023PubMedGoogle Scholar
  62. 62.
    Harach HR, Franssila KO, Wasenius V-M, et al (1985) Occult papillary carcinoma of the thyroid: a “normal” finding in Finland. A systematic autopsy study. Cancer 56:531–538PubMedCrossRefGoogle Scholar
  63. 63.
    Harigopal M, Sahoo S, Recant WM, et al (2004) Fine-needle aspiration of Riedel’s disease: report of a case and review of the literature. Diagn Cytopathol 30:193–197PubMedCrossRefGoogle Scholar
  64. 64.
    Hsu C, Boey J (1987) Diagnostic pitfalls in the fine needle aspiration of thyroid nodules: a study of 555 cases in Chinese patients. Acta Cytol 31:699–704PubMedGoogle Scholar
  65. 65.
    Jain M, Khan A, Patwardhan N, et al (2001) Follicular variant of papillary thyroid carcinoma: a comparative study of histopathologic features and cytology results in 141 patients. Endocr Pract 7:139–142Google Scholar
  66. 66.
    Jayaram G (1983) Problems in the interpretation of Hurthle cell populations in fine needle aspirates from the thyroid. Acta Cytol 27:84–85PubMedGoogle Scholar
  67. 67.
    Jayaram G, Marwaha RK, Gupta RK, et al (1987) Cytomorphologic aspects of thyroiditis: a study of 51 cases with functional, immunologic and ultrasonographic data. Acta Cytol 31:687–693PubMedGoogle Scholar
  68. 68.
    Jayaram G, Razak A, Ghan SK, et al (1999) Fine needle aspiration cytology of the thyroid: a review of experience in 1854 cases. Malays J Pathol 21:17–27PubMedGoogle Scholar
  69. 69.
    Kaur A, Jayaram G (1990) Thyroid tumors: cytomorphology of medullary, clinically anaplastic, and miscellaneous thyroid neoplasms. Diagn Cytopathol 6:383–389PubMedGoogle Scholar
  70. 70.
    Kaur A, Jayaram G (1991) Thyroid tumors: cytomorphology of papillary carcinoma. Diagn Cytopathol 7:462–472PubMedGoogle Scholar
  71. 71.
    Kelman AS, Rathan A, Leibowitz J, et al (2001) Thyroid cytology and the risk of malignancy in thyroid nodules: importance of nuclear atypia in indeterminate specimens. Thyroid 11:271–277PubMedCrossRefGoogle Scholar
  72. 72.
    Khurana KK, Labrador E, Izquierdo R, et al (1999) The role of fine-needle aspiration biopsy in the management of thyroid nodules in children, adolescents, and young adults: a multi-institutional study. Thyroid 9:383–386PubMedGoogle Scholar
  73. 73.
    Kim SJ, Kim EK, Park CS, et al (2003) Ultrasound-guided fine-needle aspiration biopsy in nonpalpable thyroid nodules: is it useful in infracentimetric nodules? Yonsei Med J 44:635–640PubMedGoogle Scholar
  74. 74.
    Kini SR, Miller JM, Hamburger JI, et al (1985) Cytopathology of follicular lesions of the thyroid gland. Diagn Cytopathol 1:123–132PubMedGoogle Scholar
  75. 75.
    Klemi PJ, Joensuu H, Nylamo E (1991) Fine needle aspiration biopsy in the diagnosis of thyroid nodules. Acta Cytol 35:434–438PubMedGoogle Scholar
  76. 76.
    Ko HM, Jhu IK, Yang SH, et al (2003) Clinicopathologic analysis of fine needle aspiration cytology of the thyroid. A review of 1,613 cases and correlation with histopathologic diagnoses. Acta Cytol 47:727–732PubMedGoogle Scholar
  77. 77.
    Kollur SM, El Sayed S, El Hag IA (2003) Follicular thyroid lesions coexisting with Hashimoto’s thyroiditis: incidence and possible sources of diagnostic errors. Diagn Cytopathol 28:35–38PubMedCrossRefGoogle Scholar
  78. 78.
    Kon YC, DeGroot LJ (2003) Painful Hashimoto’s thyroiditis as an indication for thyroidectomy: clinical characteristics and outcome in seven patients. J Clin Endocrinol Metab 88:2667–2672PubMedCrossRefGoogle Scholar
  79. 79.
    Lam KY, Lo CY (1998) Metastatic tumors of the thyroid gland. Arch Pathol Lab Med 122:37–41PubMedGoogle Scholar
  80. 80.
    Lawrence W Jr, Kaplan BJ (2002) Diagnosis and management of patients with thyroid nodules. J Surg Oncol 80:157–170PubMedCrossRefGoogle Scholar
  81. 81.
    Layfield LJ, Reichman A, Bottles K, et al (1992) Clinical determinants for the management of thyroid nodules by fine-needle aspiration cytology. Arch Otolaryngol Head Neck Surg 118:717–721PubMedGoogle Scholar
  82. 82.
    Leung C-S, Hartwick RWJ, Bedard YC (1993) Correlation of cytologic and histologic features in variants of papillary carcinoma of the thyroid. Acta Cytol 37:645–650PubMedGoogle Scholar
  83. 83.
    Liel Y, Ariad S, Barchana M (2001) Long-term follow-up of patients with initially benign thyroid fine needle aspirations. Thyroid 11:775–778PubMedCrossRefGoogle Scholar
  84. 84.
    Lin HS, Komisar A, Opher E, et al (2000) Follicular variant of papillary carcinoma: the diagnostic limitation of preoperative fine-needle aspiration and intraoperative frozen section evaluation. Laryngoscope 110:1431–1436PubMedCrossRefGoogle Scholar
  85. 85.
    Liu LH, Bakhos R, Wojcik EM (2001) Concomitant papillary thyroid carcinoma and Hashimoto’s thyroiditis. Semin Diagn Pathol 18:99–103PubMedGoogle Scholar
  86. 86.
    LiVolsi VA (1992) Papillary neoplasms of the thyroid: pathologic and prognostic features. Anat Pathol 97:426–434Google Scholar
  87. 87.
    LiVolsi VA, Gupta PK (1992) Thyroid fine-needle aspiration: intranuclear inclusions, nuclear grooves and psammoma bodies-paraganglioma-like adenoma of the thyroid. Diagn Cytopathol 8:82–84PubMedGoogle Scholar
  88. 88.
    Lo Gerfo P, Starker P, Weber C, et al (1985) Incidence of cancer in surgically treated thyroid nodules based on method of selection. Surgery 98:1197–1201PubMedGoogle Scholar
  89. 89.
    Lowhagen T, Sprenger E (1974) Cytologic presentation of thyroid tumors in aspiration biopsy smear: a review of 60 cases. Acta Cytol 18:192–197PubMedGoogle Scholar
  90. 90.
    Matsuzuka F, Miyauchi A, Katayama S, et al (1993) Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases. Thyroid 3:93–99PubMedGoogle Scholar
  91. 91.
    Mazzaferri EL, de los Santos ET, Rofagha-Keyhani S, et al (1988) Solitary thyroid nodule: diagnosis and management. Med Clin North Am 72:1177–1211PubMedGoogle Scholar
  92. 92.
    McHenry CR, Thomas SR, Slusarczyk SJ, et al (1999) Follicular or Hurthle cell neoplasm of the thyroid: can clinical factors be used to predict carcinoma. Surgery 126:798–802PubMedGoogle Scholar
  93. 93.
    Mendelsohn G, Bigner SH, Eggleston JC, et al (1980) Anaplastic variants of medullary thyroid carcinoma: a lightmicroscopic and immunohistochemical study. Am J Surg Path 4:333–341PubMedCrossRefGoogle Scholar
  94. 94.
    Merchant SH, Izquierdo R, Khurna KK (2000) Is repeated fine-needle aspiration cytology useful in the management of patients with benign nodular thyroid disease? Thyroid 10:489–492PubMedGoogle Scholar
  95. 95.
    Miller TR, Bottles K, Holly EA, et al (1986) A step-wise logistic regression analysis of papillary carcinoma of the thyroid. Acta Cytol 30:285–293PubMedGoogle Scholar
  96. 96.
    Mirallie E, Rigaud J, Mathonnet M, et al (2005) Management and prognosis of metastases to the thyroid gland. J Am Coll Surg 200:203–207PubMedCrossRefGoogle Scholar
  97. 97.
    Nguyen GK, Akin MR (2001) Cytopathology of insular carcinoma of the thyroid. Diagn Cytopathol 25:325–330PubMedCrossRefGoogle Scholar
  98. 98.
    Ofner C, Hittmair A, Kroll I, et al (1994) Fine needle aspiration cytodiagnosis of subacute (de Quervain’s) thyroiditis in an endemic goiter area. Cytopathology 5:33–40PubMedGoogle Scholar
  99. 99.
    Pelizzo MR, Piotto A, Rubello D, et al (1990) High prevalence of occult papillary thyroid carcinoma in a surgical series for benign thyroid disease. Tumori 76:255–257PubMedGoogle Scholar
  100. 100.
    Pietribiasi F, Sapino A, Papotti M, et al (1990) Cytologic features of poorly differentiated ‘insular’ carcinoma of the thyroid, as revealed by fine-needle aspiration biopsy. Am J Clin Pathol 94:687–692PubMedGoogle Scholar
  101. 101.
    Poropatich C, Marcus D, Oertel YC (1994) Hashimoto’s thyroiditis: fine-needle aspiration of 50 asymptomatic cases. Diagn Cytopathol 11:141–145PubMedGoogle Scholar
  102. 102.
    Raber W, Kaserer K, Niederle B, et al (2000) Risk factors for malignancy of thyroid nodules initially identified as follicular neoplasia by fine-needle aspiration: results of a prospective study of one hundred twenty patients. Thyroid 10:109–112CrossRefGoogle Scholar
  103. 103.
    Ravetto C, Colombo L, Dottorini ME (2000). Usefulness of fine-needle aspiration in the diagnosis of thyroid carcinoma: a retrospective study in 37,895 patients. Cancer 90:357–363PubMedCrossRefGoogle Scholar
  104. 104.
    Ravinsky E, Safneck JR (1988) Differentiation of Hashimoto’s thyroiditis from thyroid neoplasms in fine needle aspirates. Acta Cytol 32:854–861PubMedGoogle Scholar
  105. 105.
    Renshaw AA (2001) Accuracy of fine-needle aspiration using receiver operator characteristic curves. Am J Clin Pathol 117:493–494Google Scholar
  106. 106.
    Rosai J (1993) Papillary carcinoma. Monogr Pathol 35:138–163PubMedGoogle Scholar
  107. 107.
    Rosen IB, Walfish PG, Nikore V (1985) Pregnancy and surgical thyroid disease. Surgery 98:1135–1140PubMedGoogle Scholar
  108. 108.
    Samaan NA, Ordonez NG (1990) Uncommon types of thyroid cancer. Endocrinol Metab Clin North Am 19:637–648PubMedGoogle Scholar
  109. 109.
    Sangalli G, Serio G, Zampatti C, et al (2001) Fine needle aspiration cytology of primary lymphoma of the thyroid: a report of 17 cases. Cytopathology 12:257–264PubMedCrossRefGoogle Scholar
  110. 110.
    Sclabas GM, Staerkel GA, Shapiro SE (2003) Fine-needle aspiration of the thyroid and correlation with histopathology in a contemporary series of 240 patients. Am J Surg 186:702–709PubMedCrossRefGoogle Scholar
  111. 111.
    Scopa CD, Melachrinous M, Saradopoulou C, et al (1993) The significance of the grooved nucleus in thyroid lesions. Mod Pathol 6:691–694PubMedGoogle Scholar
  112. 112.
    Settakorn J, Chaiwun B, Thamprasert K, et al (2001) Fine needle aspiration of the thyroid gland. J Med Assoc Thai 84:1401–1406PubMedGoogle Scholar
  113. 113.
    Silver SA, Busseniers AE (1995) Cytologic criteria for differentiating neoplastic from nonneoplastic Hurthle cell lesions by fine needle aspiration. Mod Pathol 8:44AGoogle Scholar
  114. 114.
    Silverman JF, West RL, Larkin EW, et al (1986) The role of fine needle aspiration biopsy in the rapid diagnosis and management of thyroid neoplasm. Cancer 57:1164–1170PubMedCrossRefGoogle Scholar
  115. 115.
    Suen KS, Quenville NF (1983) Fine needle aspiration biopsy of the thyroid gland: a study of 304 cases. J Clin Pathol 36:1036–1045PubMedGoogle Scholar
  116. 116.
    Tabaqchali MA, Hanson JM, Johnson SJ, et al (2000) Thyroid aspiration cytology in Newcastle: a six year cytology/histology correlation study. Ann R Coll Surg Engl 82:149–155PubMedGoogle Scholar
  117. 117.
    Tollin SR, Mery GM, Jelveh N, et al (2000) The use of fine-needle aspiration biopsy under ultrasound guidance to assess the risk of malignancy in patients with multinodular goiter. Thyroid 10:235–241PubMedCrossRefGoogle Scholar
  118. 118.
    Vodanoviv S, Crepinko I, Smoje J (1993) Morphologic diagnosis of Hurthle cell tumors of the thyroid gland. Acta Cytol 37:317–322Google Scholar
  119. 119.
    Watts NB (1987) Carcinoma metastatic to the thyroid: prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci 293:13–17PubMedCrossRefGoogle Scholar
  120. 120.
    Yang YJ, Khurana KK (2001) Diagnostic utility of intracytoplasmic lumen and transgressing vessels in evaluation of Hurthle cell lesions by fine-needle aspiration. Arch Pathol Lab Med 125:1031–1035PubMedGoogle Scholar
  121. 121.
    Yang GC, Liebeskind D, Messina AV (2001) Ultrasound-guided fine-needle aspiration of the thyroid assessed by Ultrafast Papanicolaou stain: data from 1135 biopsies with a two to six-year follow-up. Thyroid 11:581–589PubMedCrossRefGoogle Scholar
  122. 122.
    Ylagan LR, Farkas T, Dehner LP (2004) Fine needle aspiration of the thyroid: a cytohistologic correlation and study of discrepant cases. Thyroid 14:35–41PubMedCrossRefGoogle Scholar
  123. 123.
    Zeppa P, Vetrani A, Marino M, et al (1990) Fine needle aspiration cytology of medullary thyroid carcinoma: a review of 18 cases. Cytopathology 1:35–44PubMedGoogle Scholar
  124. 124.
    Zeppa P, Benincasa G, Lucariello A, et al (2001) Association of different pathologic processes of the thyroid gland in fine needle aspiration samples. Acta Cytol 45:347–352PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Anne E. Busseniers
    • 1
    • 2
  • Susan A. Silver
    • 1
  1. 1.Metropolitan FNA ServiceWashington, DC; BethesdaUSA
  2. 2.Department of PathologyVrije Universiteit BrusselsBrusselsBelgium

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