Outcomes Analysis in Parathyroid Surgery

  • Leon D. Boudourakis
  • Julie Ann Sosa


Primary Hyperparathyroidism Parathyroid Adenoma Hospital Volume Parathyroid Surgery Endocrine Surgery 
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  1. 1.
    Wermers RA, Khosla S, et al (1997) The rise and fall of primary hyperparathyroidism: a population-based study in Rochester, Minnesota, 1965–1992. Ann Intern Med 126:433–440PubMedGoogle Scholar
  2. 2.
    Sosa JA, Powe NR, et al (1998) Cost implications of different surgical management strategies for primary hyperparathyroidism. Surgery 124:1028–1035; discussion 1035–1036PubMedCrossRefGoogle Scholar
  3. 3.
    Melton LJ 3rd (2002) The epidemiology of primary hyperparathyroidism in North America. J Bone Miner Res 17(suppl 2):N12–N17PubMedGoogle Scholar
  4. 4.
    Owen R (1862) On the anatomy of the Indian rhinoceros (Rh. Unicornis, L). Trans Zool Soc Lond 4:31–58Google Scholar
  5. 5.
    Carney JA (1996) The glandulae parathyroideae of Ivar Sandström. Contributions from two continents. Am J Surg Pathol 20:1123–1144PubMedCrossRefGoogle Scholar
  6. 6.
    Organ CH Jr (2000) The history of parathyroid surgery, 1850–1996: the Excelsior Surgical Society 1998 Edward D. Churchill Lecture. J Am Coll Surg 191:284–299PubMedCrossRefGoogle Scholar
  7. 7.
    Bauer FA, Aub JC (1930) A case of osteitis fibrosa cystica (osteomalacia?) with evidence of hyperactivity of the parathyroid bodies: a metabolic study. J Clin Invest 8:229–248PubMedCrossRefGoogle Scholar
  8. 8.
    Mandl F (1926) Attempt to treat generalized fibrous osteitis by extirpation of parathyroid tumor. Zentralbl F Chir 53:260–264Google Scholar
  9. 9.
    Barr D, Bulger H, Dixon H (1929) Hyperparathyroidism. JAMA 92:951–952Google Scholar
  10. 10.
    Guy C (1929) Tumors of the parathyroid glands. Surg Gynecol Obstet 48:557–565Google Scholar
  11. 11.
    Luft HS, Bunker JP, Enthoven AC (1979) Should operations be regionalized? The empirical relation between surgical volume and mortality. N Engl J Med 301:1364–1369PubMedCrossRefGoogle Scholar
  12. 12.
    Bilezikian JP, Potts JT Jr, et al (2002) Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century. J Clin Endocrinol Metab 87:5353–5361PubMedCrossRefGoogle Scholar
  13. 13.
    National Institutes of Health (1990) Diagnosis and management of asymptomatic primary hyperparathyroidism. National Institutes of Health Consensus Development Conference, 29–31 October 1990. Consens Statement 8:1–18Google Scholar
  14. 14.
    Chen H, Parkerson S, Udelsman R (1998) Parathyroidectomy in the elderly: do the benefits outweigh the risks? World J Surg 22:531–535; discussion 535–536PubMedCrossRefGoogle Scholar
  15. 15.
    Birkmeyer JD, Siewers AE, et al (2002) Hospital volume and surgical mortality in the United States. N Engl J Med 346:1128–1137PubMedCrossRefGoogle Scholar
  16. 16.
    Sosa JA, Powe NR, et al (1998) Profile of a clinical practice: thresholds for surgery and surgical outcomes for patients with primary hyperparathyroidism. A national survey of endocrine surgeons. J Clin Endocrinol Metab 83:2658–2665PubMedCrossRefGoogle Scholar
  17. 17.
    Doppman JL, Miller DL (1991) Localization of parathyroid tumors in patients with asymptomatic hyperparathyroidism and no previous surgery. J Bone Miner Res 6(suppl 2):S153–S158; discussion S159PubMedCrossRefGoogle Scholar
  18. 18.
    Saunders BD, Wainess RM, et al (2003) Who performs endocrine operations in the United States? Surgery 134:924–931; discussion 931PubMedCrossRefGoogle Scholar
  19. 19.
    Harness JK, Organ CH Jr, Thompson NW (1995) Operative experience of U.S. general surgery residents in thyroid and parathyroid disease. Surgery 118:1063–1069; discussion 1069–1070PubMedCrossRefGoogle Scholar
  20. 20.
    Jarman BT, Miller MR, et al (2004) The 80-hour work week: will we have less-experienced graduating surgeons? Curr Surg 61:612–615PubMedCrossRefGoogle Scholar
  21. 21.
    Willeke F, Willeke M, et al (1998) Effect of surgeon expertise on the outcome in primary hyperparathyroidism. Arch Surg 133:1066–1070; discussion 1071PubMedCrossRefGoogle Scholar
  22. 22.
    Irvin GL 3rd, Prudhomme DL, et al (1994) A new approach to parathyroidectomy. Ann Surg 219:574–579; discussion 579–581PubMedCrossRefGoogle Scholar
  23. 23.
    Sackett WR, Barraclough B, et al (2002) Worldwide trends in the surgical treatment of primary hyperparathyroidism in the era of minimally invasive parathyroidectomy. Arch Surg 137:1055–1059PubMedCrossRefGoogle Scholar
  24. 24.
    Bergenfelz A, Lindblom P, et al (2002) Unilateral versus bilateral neck exploration for primary hyperparathyroidism: a prospective randomized controlled trial. Ann Surg 236:543–551PubMedCrossRefGoogle Scholar
  25. 25.
    Fahy BN, Bold RJ, et al (2002) Modern parathyroid surgery: a cost-benefit analysis of localizing strategies. Arch Surg 137:917–922; discussion 922–923PubMedCrossRefGoogle Scholar
  26. 26.
    Tarazi R, Esselstyn CB Jr, Coccia MR (1984) Parathyroidectomy for primary hyperparathyroidism: early discharge. Surgery 96:1158–1162PubMedGoogle Scholar
  27. 27.
    Udelsman R (2002) Six hundred fifty-six consecutive explorations for primary hyperparathyroidism. Ann Surg 235:665–670; discussion 670–672PubMedCrossRefGoogle Scholar
  28. 28.
    Joborn C, Joborn H, et al (1988) Maximal isokinetic muscle strength in patients with primary hyperparathyroidism before and after parathyroid surgery. Br J Surg 75:77–80PubMedGoogle Scholar
  29. 29.
    Christiansen P, Steiniche T, et al (1999) Primary hyperparathyroidism: effect of parathyroidectomy on regional bone mineral density in Danish patients: a three-year follow-up study. Bone 25:589–595PubMedCrossRefGoogle Scholar
  30. 30.
    Vestergaard P, Mosekilde L (2003) Cohort study on effects of parathyroid surgery on multiple outcomes in primary hyperparathyroidism. BMJ 327:530–534PubMedCrossRefGoogle Scholar
  31. 31.
    Salahudeen AK, Thomas TH, et al (1989) Hypertension and renal dysfunction in primary hyperparathyroidism: effect of parathyroidectomy. Clin Sci (Colch) 76:289–296PubMedGoogle Scholar
  32. 32.
    Silverberg SJ, Shane E, et al (1999) A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery. N Engl J Med 341:1249–1255PubMedCrossRefGoogle Scholar
  33. 33.
    Lundgren E, Lind L, et al (2001) Increased cardiovascular mortality and normalized serum calcium in patients with mild hypercalcemia followed up for 25 years. Surgery 130:978–985PubMedCrossRefGoogle Scholar
  34. 34.
    Joborn C, Hetta J, et al (1989) Self-rated psychiatric symptoms in patients operated on because of primary hyperparathyroidism and in patients with long-standing mild hypercalcemia. Surgery 105:72–78PubMedGoogle Scholar
  35. 35.
    Roman S, Sosa JA, et al (2005) Parathyroidectomy improves neurocognitive deficits in patients with primary hyperparathyroidism. Surgery (in press)Google Scholar
  36. 36.
    Heath H 3rd, Hodgson SF, Kennedy MA (1980) Primary hyperparathyroidism. Incidence, morbidity, and potential economic impact in a community. N Engl J Med 302:189–193PubMedCrossRefGoogle Scholar
  37. 37.
    Quiros RM, Alef MJ, et al (2003) Health-related quality of life in hyperparathyroidism measurably improves after parathyroidectomy. Surgery 134:675–681; discussion 681–683PubMedCrossRefGoogle Scholar
  38. 38.
    Tibblin S, Palsson N, Rydberg J (1983) Hyperparathyroidism in the elderly. Ann Surg 197:135–138PubMedCrossRefGoogle Scholar
  39. 39.
    Mahadevia PJ, Sosa JA, et al (2003) Clinical management of primary hyperparathyroidism and thresholds for surgical referral: a national study examining concordance between practice patterns and consensus panel recommendations. Endocr Pract 9:494–503PubMedGoogle Scholar
  40. 40.
    Markey DW, McGowan J, Hanks JB (2000) The effect of clinical pathway implementation on total hospital costs for thyroidectomy and parathyroidectomy patients. Am Surg 66:533–538; discussion 538–539PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Leon D. Boudourakis
    • 1
  • Julie Ann Sosa
    • 2
  1. 1.Yale University School of MedicineNew HavenUSA
  2. 2.Sections of Oncologic, Endocrine, and General SurgeryYale University School of MedicineNew HavenUSA

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