Thyroid Lymphoma and Other Metastatic Lesions

  • Rebecca S. Sippel
  • Herbert Chen


Thyroid Cancer Thyroid Gland Metastatic Lesion Thyroid Nodule Malt Lymphoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Roeher HD, Simon D (1999) Surgical therapy of thyroid cancer. G Chir 20:5–8PubMedGoogle Scholar
  2. 2.
    Doria R, Jekel JF, Cooper DL (1994) Thyroid lymphoma. The case for combined modality therapy. Cancer 73:200–206PubMedCrossRefGoogle Scholar
  3. 3.
    Compagno J, Oertel JE (1980) Malignant lymphoma and other lymphoproliferative disorders of the thyroid gland. A clinicopathologic study of 245 cases. Am J Clin Pathol 74:1–11PubMedGoogle Scholar
  4. 4.
    Samaan NA, Ordonez NG (1990) Uncommon types of thyroid cancer. Endocrinol Metab Clin North Am 19:637–648PubMedGoogle Scholar
  5. 5.
    Derringer GA, Thompson LD, Frommelt RA, Bijwaard KE, Heffess CS, Abbondanzo SL (2000) Malignant lymphoma of the thyroid gland: a clinicopathologic study of 108 cases. Am J Surg Pathol 24:623–639PubMedCrossRefGoogle Scholar
  6. 6.
    Ansell SM, Grant CS, Habermann TM (1999) Primary thyroid lymphoma. Semin Oncol 26:316–323PubMedGoogle Scholar
  7. 7.
    Pasieka JL (2000) Hashimoto’s disease and thyroid lymphoma: role of the surgeon. World J Surg 24:966–970PubMedCrossRefGoogle Scholar
  8. 8.
    Thieblemont C, Mayer A, Dumontet C, Barbier Y, Callet-Bauchu E, Felman P, Berger F, Ducottet X, Martin C, Salles G, Orgiazzi J, Coiffier B (2002) Primary thyroid lymphoma is a heterogeneous disease. J Clin Endocrinol Metab 87:105–111PubMedCrossRefGoogle Scholar
  9. 9.
    Holm LE, Blomgren H, Lowhagen T (1985) Cancer risks in patients with chronic lymphocytic thyroiditis. N Engl J Med 312:601–604PubMedCrossRefGoogle Scholar
  10. 10.
    Matsuzuka F, Miyauchi A, Katayama S, Narabayashi I, Ikeda H, Kuma K, Sugawara M (1993) Clinical aspects of primary thyroid lymphoma: diagnosis and treatment based on our experience of 119 cases. Thyroid 3:93–99PubMedGoogle Scholar
  11. 11.
    Herrmann R, Panahon AM, Barcos MP, Walsh D, Stutzman L (1980) Gastrointestinal involvement in non-Hodgkin’s lymphoma. Cancer 46:215–222PubMedCrossRefGoogle Scholar
  12. 12.
    Tupchong L, Hughes F, Harmer CL (1986) Primary lymphoma of the thyroid: clinical features, prognostic factors, and results of treatment. Int J Radiat Oncol Biol Phys 12:1813–1821PubMedGoogle Scholar
  13. 13.
    Krueger GR, Medina JR, Klein HO, Konrads A, Zach J, Rister M, Janik G, Evers KG, Hirano T, Kitamura H, Bedoya VA (1983) A new working formulation of non-Hodgkin’s lymphomas. A retrospective study of the new NCI classification proposal in comparison to the Rappaport and Kiel classifications. Cancer 52:833–840PubMedCrossRefGoogle Scholar
  14. 14.
    Skarsgard ED, Connors JM, Robins RE (1991) A current analysis of primary lymphoma of the thyroid. Arch Surg 126:1199–1203PubMedGoogle Scholar
  15. 15.
    Harris NL, Jaffe E, Stein H, et al (1994) A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84:1361–1392PubMedGoogle Scholar
  16. 16.
    Ishikawa H, Tamaki Y, Takahashi M, Higuchi K, Sakaino K, Nonaka T, Shioya M, Mitsuhashi N, Niibe H (2002) Comparison of primary thyroid lymphoma with anaplastic thyroid carcinoma on computed tomographic imaging. Radiat Med 9–15Google Scholar
  17. 17.
    Tsang RW, Gospodarowicz MK, Sutcliffe SB, Sturgeon JF, Panzarella T, Patterson BJ (1993) Non-Hodgkin’s lymphoma of the thyroid gland: prognostic factors and treatment outcome. The Princess Margaret Hospital Lymphoma Group. Int J Radiat Oncol Biol Phys 27:599–604PubMedGoogle Scholar
  18. 18.
    Fisher RI, Gaynor ER, Dahlberg S, Oken MM, Grogan TM, Mize EM, Glick JH, Coltman CA Jr, Miller TP (1993) Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin’s lymphoma. N Engl J Med 328:1002–1006PubMedCrossRefGoogle Scholar
  19. 19.
    DiBiase SJ, Grigsby PW, Guo C, Lin HS, Wasserman TH (2004) Outcome analysis for stage IE and IIE thyroid lymphoma. Am J Clin Oncol 27:178–184PubMedCrossRefGoogle Scholar
  20. 20.
    Ha CS, Shadle KM, Medeiros LJ, Wilder RB, Hess MA, Cabanillas F, Cox JD (2001) Localized non-Hodgkin lymphoma involving the thyroid gland. Cancer 91:629–635PubMedCrossRefGoogle Scholar
  21. 21.
    Udelsman R, Chen H (1999) The current management of thyroid cancer. Adv Surg 33:1–27PubMedGoogle Scholar
  22. 22.
    Cha C, Chen H, Westra W, Udelsman R (2002) Primary thyroid lymphoma: can the diagnosis be made solely by fine-needle aspiration? Ann Surg Oncol 9:298–302PubMedCrossRefGoogle Scholar
  23. 23.
    Rosen IB, Sutcliffe SB, Gospodarowicz MK, Chua T, Simpson WJ (1988) The role of surgery in the management of thyroid lymphoma. Surgery 104:1095–1099PubMedGoogle Scholar
  24. 24.
    Pyke CM, Grant CS, Habermann TM, Kurtin PJ, van Heerden JA, Bergstralh EJ, Kunselman A, Hay ID (1992) Non-Hodgkin’s lymphoma of the thyroid: is more than biopsy necessary? World J Surg 16:604–609PubMedCrossRefGoogle Scholar
  25. 25.
    Klyachkin ML, Schwartz RW, Cibull M, Munn RK, Regine WF, Kenady DE, McGrath PC, Sloan DA (1998) Thyroid lymphoma: is there a role for surgery? Am Surg 64:234–238PubMedGoogle Scholar
  26. 26.
    Sippel RS, Gauger PG, Angelos P, Thompson NW, Mack E, Chen H (2002) Palliative thyroidectomy for malignant lymphoma of the thyroid. Ann Surg Oncol 9:907–911PubMedCrossRefGoogle Scholar
  27. 27.
    Wirtzfeld DA, Winston JS, Hicks WL Jr, Loree TR (2001) Clinical presentation and treatment of non-Hodgkin’s lymphoma of the thyroid gland. Ann Surg Oncol 8:338–341PubMedGoogle Scholar
  28. 28.
    Pedersen RK, Pedersen NT (1996) Primary non-Hodgkin’s lymphoma of the thyroid gland: a population based study. Histopathology 28:25–32PubMedCrossRefGoogle Scholar
  29. 29.
    Belal AA, Allam A, Kandil A, El Husseiny G, Khafaga Y, Al Rajhi N, Ahmed G, Gray A, Ajarim D, Schultz H, Ezzat A (2001) Primary thyroid lymphoma: a retrospective analysis of prognostic factors and treatment outcome for localized intermediate and high grade lymphoma. Am J Clin Oncol 24:299–305PubMedCrossRefGoogle Scholar
  30. 30.
    Laing RW, Hoskin P, Hudson BV, Hudson GV, Harmer C, Bennett MH, MacLennan KA (1994) The significance of MALT histology in thyroid lymphoma: a review of patients from the BNLI and Royal Marsden Hospital. Clin Oncol (R Coll Radiol) 6:300–304CrossRefGoogle Scholar
  31. 31.
    Willis RA (1931) Metastatic tumors in the thyroid gland. Am J Pathol 7:187–208PubMedGoogle Scholar
  32. 32.
    Lin JD, Weng HF, Ho YS (1998) Clinical and pathological characteristics of secondary thyroid cancer. Thyroid 8:149–153PubMedCrossRefGoogle Scholar
  33. 33.
    Michelow PM, Leiman G (1995) Metastases to the thyroid gland: diagnosis by aspiration cytology [see comment]. Diagn Cytopathol 13:209–213PubMedGoogle Scholar
  34. 34.
    Lin SY, Sheu WH, Chang MC, Tang KT, Lee TI, Lin HD (2002) Diagnosis of thyroid metastasis in cancer patients with thyroid mass by fine needle aspiration cytology and ultrasonography. Chung Hua I Hsueh Tsa Chih 65:101–105PubMedGoogle Scholar
  35. 35.
    Watts NB (1987) Carcinoma metastatic to the thyroid: prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci 293:13–17PubMedCrossRefGoogle Scholar
  36. 36.
    Lam KY, Lo CY (1998) Metastatic tumors of the thyroid gland: a study of 79 cases in Chinese patients. Arch Pathol Lab Med 122:37–41PubMedGoogle Scholar
  37. 37.
    Chen H, Nicol TL, Udelsman R (1999) Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg 23:177–180; discussion 181PubMedCrossRefGoogle Scholar
  38. 38.
    Wood K, Vini L, Harmer C (2004) Metastases to the thyroid gland: the Royal Marsden experience. Eur J Surg Oncol 30:583–588PubMedCrossRefGoogle Scholar
  39. 39.
    Kihara M, Yokomise H, Yamauchi A (2004) Metastasis of renal cell carcinoma to the thyroid gland 19 years after nephrectomy: a case report. Auris Nasus Larynx 31:95–100PubMedCrossRefGoogle Scholar
  40. 40.
    Heffess CS, Wenig BM, Thompson LD (2002) Metastatic renal cell carcinoma to the thyroid gland: a clinicopathologic study of 36 cases. Cancer 95:1869–1878PubMedCrossRefGoogle Scholar
  41. 41.
    Nakhjavani MK, Gharib H, Goellner JR, van Heerden JA (1997) Metastasis to the thyroid gland. A report of 43 cases. Cancer 79:574–578PubMedCrossRefGoogle Scholar
  42. 42.
    Rosen IB, Walfish PG, Bain J, Bedard YC (1995) Secondary malignancy of the thyroid gland and its management. Ann Surg Oncol 2:252–256PubMedCrossRefGoogle Scholar
  43. 43.
    Hacker U, Lenz G, Brehm G, Muller-Hocker J, Schalhorn A, Hiddemann W (2003) Metastasis of a rectal adenocarcinoma to the thyroid gland: diagnostic and therapeutic implications. Anticancer Res 23:4973–4976PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  • Rebecca S. Sippel
    • 1
  • Herbert Chen
    • 2
  1. 1.Department of SurgeryUniversity of Wisconsin, H4/710 Clinical Science CenterMadisonUSA
  2. 2.Department of SurgeryUniversity of Wisconsin, H4/750 Clinical Science CenterMadisonUSA

Personalised recommendations