Nomenclature
EC number
2.6.1.64
Systematic name
L-glutamine:phenylpyruvate aminotransferase
Recommended name
glutamine-phenylpyruvate transaminase
Synonyms
EC 2.6.1.14 lt;6gt; (lt;6gt; maybe identical [11]) [11]
EC 2.6.1.15 lt;1, 6gt; (lt;6gt; identical with [16]) [7, 16]
EC 2.6.1.7 lt;6gt; (lt;6gt; maybe identical [11]) [11]
GTK lt;6gt; [13, 161
KAT/GTK lt;6gt; [11, 16]
cysteine conjugate β-lyase/glutamine transaminase K lt;6gt; [14]
glutamine transaminase K lt;2, 3, 6gt; [1, 5, 6, 9, 12, 13, 15]
glutamine transaminase L lt;6gt; [1, 5, 6]
glutamine-phenylpyruvate aminotransferase
histidine pyruvate aminotransferase isoenzyme 2 lt;6gt; [4]
kynurenine aminotransferase/glutamine transaminase K lt;6gt; [11, 16]
CAS registry number
68518-06-9
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cooper, A.J.L.; Meister, A.: Isolation and properties of a new glutamine transaminase from rat kidney. J. Biol. Chem., 249, 2554–2561 (1974)
Van Leuven, F.: Highly purified glutamine transaminase from rat brain. Physical and kinetic properties. Eur. J. Biochem., 58, 153–158 (1975)
Van Leuven, F.: Glutamine transaminase from brain tissue. Further studies on kinetic properties and specificity of the enzyme. Eur. J. Biochem., 65, 271–274 (1976)
Noguchi, T.; Okuno, E.; Kido, R.: Identity of rat kidney histidine-pyruvate aminotransferase with glutamine-oxo acid aminotransferase. Biochem. J., 161, 177–179 (1977)
Cooper, A.J.L.: Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between l-phenylalanine and α-keto-γ-methiolbutyrate. Anal. Biochem., 89, 451–460 (1978)
Cooper, A.J.L.; Meister, A.: Glutamine transaminase K from rat kidney. Methods Enzymol., 113, 344–349 (1985)
Ricci, G.; Nardini, M.; Federici, G.; Cavallini, D.: The transamination of l-cystathionine, l-cystine and related compounds by a bovine kidney transaminase. Eur. J. Biochem., 157, 57–63 (1986)
Wu, G.; Thompson, J.R.; Baracos, V.E.: Glutamine metabolism in skeletal muscles from the broiler chick (Gallus domesticus) and the laboratory rat (Rattus norvegicus). Biochem. J., 274, 769–774 (1991)
Makar, T.K.; Nedergaard, M.; Preuss, A.; Hertz, L.; Cooper, A.J.: Glutamine transaminase K and ω-amidase activities in primary cultures of astrocytes and neurons and in embryonic chick forebrain: Marked induction of brain glutamine transaminase K at time of hatching. J. Neurochem., 62, 1983–1988 (1994)
Abraham, D.G.; Thomas, R.J.; Cooper, A.J.: Glutamine transaminase K is not a major cysteine S-conjugate β-lyase of rat kidney mitochondria: evidence that a high-molecular weight enzyme fulfills this role. Mol. Pharmacol., 48, 855–860 (1995)
Malherbe, P.; Alberati-Giani, D.; Koehler, C.; Cesura, A.M.: Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain. FEBS Lett., 367, 141–144 (1995)
Abraham, D.G.; Cooper, A.J.: Cloning and expression of a rat kidney cytosolic glutamine transaminase K that has strong sequence homology to kynurenine pyruvate aminotransferase. Arch. Biochem. Biophys., 335, 311–320 (1996)
Trevisan, A.; Cristofori, P.; Fanelli, G.; Bicciato, F.; Stocco, E.: Glutamine transaminase K intranephron localization in rats determined by urinary excretion after treatment with segment-specific nephrotoxicants. Arch. Toxicol., 72, 531–535 (1998)
Commandeur, J.N.; Andreadou, I.; Rooseboom, M.; Out, M.; de Leur, L.J.; Groot, E.; Vermeulen, N.P.: Bioactivation of selenocysteine Se-conjugates by a highly purified rat renal cysteine conjugate β-lyase/glutamine transaminase K. J. Pharmacol. Exp. Ther., 294, 753–761 (2000)
Han, Q.; Fang, J.; Li, J.: Kynurenine aminotransferase and glutamine transaminase K of Escherichia coli: identity with aspartate aminotransferase. Biochem. J., 360, 617–623 (2001)
Mosca, M.; Croci, C.; Mostardini, M.; Breton, J.; Malyszko, J.; Avanzi, N.; Toma, S.; Benatti, L.; Gatti, S.: Tissue expression and translational control of rat kynurenine aminotransferase/glutamine transaminase K mRNAs. Biochim. Biophys. Acta, 1628, 1–10 (2003)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
(2007). Glutamine-phenylpyruvate transaminase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 Transferases VIII. Springer Handbook of Enzymes, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49756-1_7
Download citation
DOI: https://doi.org/10.1007/978-3-540-49756-1_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36521-1
Online ISBN: 978-3-540-49756-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)