Skip to main content

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume 35))

  • 517 Accesses

Nomenclature

EC number

2.7.1.2

Systematic name

ATP:d-glucose 6-phosphotransferase

Recommended name

glucokinase

Synonyms

glucokinase (phosphorylating)

kinase, gluco- (phosphorylating)

CAS registry number

9001-36-9

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Baumann, P.: Glucokinase of Dictyostelium discoideum. Biochemistry, 8, 5011–5015 (1969)

    Article  PubMed  CAS  Google Scholar 

  2. Porter, E.V.; Chassy, B.M.; Holmlund, C.E.: Purification and kinetic characterization of a specific glucokinase from Streptococcus mutans OMZ70 cells. Biochim. Biophys. Acta, 709, 178–186 (1982)

    PubMed  CAS  Google Scholar 

  3. Porter, V.; Chassy, B.M.: Glucokinase from Streptococcus mutans. Methods Enzymol., 90, 25–30 (1982)

    Article  PubMed  CAS  Google Scholar 

  4. Scopes, R.K.; Testolin, V.; Stoter, A.; Griffiths-Smith, K.; Algar, E.M.: Simultaneous purification and characterization of glucokinase, fructokinase and glucose-6-phosphate dehydrogenase from Zymomonas mobilis. Biochem. J., 228, 627–634 (1985)

    PubMed  CAS  Google Scholar 

  5. Doelle, H.W.: Kinetic characteristics and regulatory mechanisms of glucokinase and fructokinase from Zymomonas mobilis. Eur. J. Appl. Microbiol. Biotechnol., 14, 241–246 (1982)

    Article  CAS  Google Scholar 

  6. Hengartner, H.; Zuber, H.: Isolation and characterization of a thermophilic glucokinase from Bacillus stearothermophilus. FEBS Lett., 37, 212–216 (1973)

    Article  PubMed  CAS  Google Scholar 

  7. Klein, D.P.; Charles, A.M.: Purification and physical properties of glucokinase from Thiobacillus versutus (A2). Can. J. Microbiol., 32, 937–941 (1986)

    Article  CAS  Google Scholar 

  8. Goward, C.R.; Hartwell, R.; Atkinson, T.; Scawen, M.D.: The purification and characterization of glucokinase from the thermophile Bacillus stearothermophilus. Biochem. J., 237, 415–420 (1986)

    PubMed  CAS  Google Scholar 

  9. Hansen, T.; Reichstein, B.; Schmid, R.; Schonheit, P.: The first archaeal ATP-dependent glucokinase, from the hyperthermophilic crenarchaeon Aeropyrum pernix, represents a monomeric, extremely thermophilic ROK glucokinase with broad hexose specificity. J. Bacteriol., 184, 5955–5965 (2002)

    Article  PubMed  CAS  Google Scholar 

  10. Sakuraba, H.; Mitani, Y.; Goda, S.; Kawarabayasi, Y.; Ohshima, T.: Cloning, expression, and characterization of the first archaeal ATP-dependent glucokinase from aerobic hyperthermophilic archaeon Aeropyrum pernix. J. Biochem., 133, 219–224 (2003)

    Article  PubMed  CAS  Google Scholar 

  11. Tomita, K.; Ikeda, T.; Takahashi, T.: Synthesis of adenosine 5′-triphosphate derivatives and their substrate activities to thermostable glucokinases. Ann. N. Y. Acad. Sci., 864, 548–551 (1998)

    Article  CAS  Google Scholar 

  12. Arora, K.K.; Pedersen, P.L.: Glucokinase of Escherichia coli: induction in response to the stress of overexpressing foreign proteins. Arch. Biochem. Biophys., 319, 574–579 (1995)

    Article  PubMed  CAS  Google Scholar 

  13. Meyer, D.; Schneider-Fresenius, C.; Horlacher, R.; Peist, R.; Boos, W.: Molecular characterization of glucokinase from Escherichia coli K-12. J. Bacteriol., 179, 1298–1306 (1997)

    PubMed  CAS  Google Scholar 

  14. Laht, S.; Karp, H.; Kotka, P.; Jarviste, A.; Alamae, T.: Cloning and characterization of glucokinase from a methylotrophic yeast Hansenula polymorpha: different effects on glucose repression in H. polymorpha and Saccharomyces cerevisiae. Gene, 296, 195–203 (2002)

    Article  PubMed  CAS  Google Scholar 

  15. Sener, A.; Malaisse, W.J.: Kinetics and specificity of human B-cell glucokinase: relevance to hexose-induced insulin release. Biochim. Biophys. Acta, 1312, 73–78 (1996)

    Article  PubMed  Google Scholar 

  16. Xu, L.Z.; Harrison, R.W.; Weber, I.T.; Pilkis, S.J.: Human β-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity. J. Biol. Chem., 270, 9939–9946 (1995)

    Article  PubMed  CAS  Google Scholar 

  17. Scopes, R.K.; Bannon, D.R.: Kinetic analysis of the activation of Zymomonas mobilis glucokinase by phosphate. Biochim. Biophys. Acta, 1249, 173–179 (1995)

    PubMed  Google Scholar 

  18. Tu, J.; Tuch, B.E.: Glucose regulates the maximal velocities of glucokinase and glucose utilization in the immature fetal rat pancreatic islet. Diabetes, 45, 1068–1075 (1996)

    Article  PubMed  CAS  Google Scholar 

  19. Takeuchi, H.; Inoue, Y.; Ishihara, H.; Oka, Y.: Overexpression of either liver type or pancreatic β cell type glucokinase via recombinant adenovirus enhances glucose oxidation in isolated rat hepatocytes. FEBS Lett., 393, 60–64 (1996)

    Article  PubMed  CAS  Google Scholar 

  20. Roncero, I.; Alvarez, E.; Vazquez, P.; Blazquez, E.: Functional glucokinase isoforms are expressed in rat brain. J. Neurochem., 74, 1848–1857 (2000)

    Article  PubMed  CAS  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2007). Glucokinase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Class 2 Transferases VIII. Springer Handbook of Enzymes, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49756-1_25

Download citation

Publish with us

Policies and ethics