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Praxis der Nephrologie pp 197–225Cite as

Chronische Niereninsuffizienz

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Die chronische Niereninsuffizienz ist Folge eines anhaltenden Nierenfunktionsverlustes. Der natürliche Verlauf der chronischen Niereninsuffizienz ist progredient. Diese Progredienz wird unabhängig von der Grunderkrankung von sekundären Faktoren beeinflusst. Als wichtigste Progressionsfaktoren betrachtet man die intraglomeruläre Hypertonie und die glomeruläre Hypertrophie. Diese sind für die adaptive Hyperfiltration und später für die Glomerulosklerose verantwortlich. Einfluss auf die Geschwindigkeit des Nierenfunktionsverlustes haben außerdem intraglomeruläre Lipid- und Kalziumphosphatablagerungen, tubulointerstitielle und hyperglykämiebedingte Schäden und die metabolische Azidose.

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(2007). Chronische Niereninsuffizienz. In: Praxis der Nephrologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-48556-8_11

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  • DOI: https://doi.org/10.1007/978-3-540-48556-8_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-48555-1

  • Online ISBN: 978-3-540-48556-8

  • eBook Packages: Medicine (German Language)

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