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Crossroads of Aging in the Nematode Caenorhabditis elegans

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Book cover The Molecular Genetics of Aging

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 29))

Abstract

Aging can be defined in three ways: (1) as a progressive increase in the probability of dying of nonaccidental causes, (2) as a progressive increase in the probability of being afflicted with a number of specific diseases, such as cancer, cardiovascular diseases, and neurodegenerative diseases, and (3) as a progressive increase in the prevalence of features that are not in themselves pathological, but which are linked to chronological age, like wrinkled skin or white hair. In recent years, several investigators have used definition (1) and the measure of life span in the nematode Caenorhabditis elegans to study genetic, cellular, and molecular mechanisms that might be responsible for the aging process in all organisms (Hekimi et al. 1998).

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Authors and Affiliations

  1. Department of Biology, 1205 Docteur Penfield Avenue, Montréal, PQ, Canada, H3A 1B1

    Siegfried Hekimi

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  1. Siegfried Hekimi
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  1. Department of Biology, McGill University, 1205 Ave. Docteur Penfield, H3A 1B1, Montréal, Quebec, Canada

    Siegfried Hekimi

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© 2000 Springer-Verlag Berlin Heidelberg

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Hekimi, S. (2000). Crossroads of Aging in the Nematode Caenorhabditis elegans . In: Hekimi, S. (eds) The Molecular Genetics of Aging. Results and Problems in Cell Differentiation, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-48003-7_5

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  • DOI: https://doi.org/10.1007/978-3-540-48003-7_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-53686-1

  • Online ISBN: 978-3-540-48003-7

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