Abstract
Photothermal spectroscopy allows to determine the light absorption within a sample depth-resolved because of the thermal diffusion length depending on the chopping frequency. Therefore, it can be used to evaluate concentration profiles of topically applied light absorbing drugs in the upper layers of human skin. A new experimental setup with Mirage-Effect detection for in vivo-measurements is described which considerably increases the measuring depth and the accuracy of the measurements at low chopping frequencies.
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© 1992 Springer-Verlag Berlin Heidelberg
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Plamann, K., Giese, K., Sennhenn, B., Harendt, N., Kölmel, K. (1992). In Vivo Evaluation of the Human Skin Permeation of Topically Applied Light Absorbing Agents by a Mirage Effect Spectrometer. In: Bićanić, D. (eds) Photoacoustic and Photothermal Phenomena III. Springer Series in Optical Sciences, vol 69. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47269-8_25
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DOI: https://doi.org/10.1007/978-3-540-47269-8_25
Publisher Name: Springer, Berlin, Heidelberg
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