Abstract
The rules that govern cellular behavior during development and regeneration of tissues are complex and enigmatic, but substantial progress is being made toward understanding the molecular basis of proliferation and differentiation. Although most of the recent mechanistic insights have been gained from studies of embryonic development, the capacity of differentiated tissues and organs to regenerate is also an intriguing and important question (Lewis 1991; Brockes 1997; Ferrari et al. 1998). The greatest challenge to understanding how damaged tissues are repaired is to identify the stem cells and to understand the molecular factors that regulate their proliferation and differentiation.
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Raymond, P.A., Hitchcock, P.F. (2000). How the Neural Retina Regenerates. In: Fini, M.E. (eds) Vertebrate Eye Development. Results and Problems in Cell Differentiation, vol 31. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-46826-4_11
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