Abstract
The actin cytoskeleton is an essential component of all eukaryotic cells. Besides its role in cell motility, it has a number of other functions, including cytokinesis, signal transduction, and the maintenance of cell shape. An essential property of the cytoskeleton is its ability to rapidly assemble and disassemble monomers of actin into F-actin filaments and this process is now known to be regulated by a number of actin-binding proteins (ABPs) of which cofilin appears to be the most widely distributed in nature. In this chapter we pose the question: does cofilin act alone in controlling actin filament assembly or is the binding of cofilin to actin modulated by other ABPs?
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Kekic, M., Nosworthy, N.J., Dedova, I., Collyer, C.A., dos Remedios, C.G. (2001). Regulation of the Cytoskeleton Assembly: a Role for a Ternary Complex of Actin with Two Actin-Binding Proteins. In: dos Remedios, C.G., Thomas, D.D. (eds) Molecular Interactions of Actin. Results and Problems in Cell Differentiation, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-46560-7_12
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DOI: https://doi.org/10.1007/978-3-540-46560-7_12
Publisher Name: Springer, Berlin, Heidelberg
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