Skip to main content
SpringerLink
Log in
Book cover

Vertebrate Myogenesis pp 81–108Cite as

Somite Patterning: a Few More Pieces of the Puzzle

  • Chapter

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 38))

Abstract

A number of excellent reviews have been written in recent years on the various aspects of somite differentiation (Christ and Ordahl 1995; Brand-Saberi et al. 1996; Lassar and Münsterberg 1996; Gossler and Hrabe de Angelis 1998; Dietrich 1999; Hirsinger et al. 2000; Stockdale et al. 2000; Tajbakhsh and Buckingham 2000, and a compilation of reviews on somitogenesis in Ordahl 2000, to cite only a few). Thus, our purpose is not to provide yet another indepth review of the ever growing literature on that subject, but, rather, to discuss some recent data and alternative views that might hopefully shed new light on some specific aspects of somite differentiation. We will mostly focus on dermomyotome and skeletal muscle differentiation. Because a considerable amount of information on this subject has been gathered in chick, most of our discussion will refer to this work. However, differences between mouse and chick somitogenesis will be pointed out when appropriate. In addition, we have integrated the data acquired from genetic studies performed in mouse, which have been crucial to our understanding of somite differentiation. Given the immense literature pertaining to this subject,it is likely that we have not cited everyone:we would like to apologize here to any of our colleagues that might feel we have overlooked their data.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ahlgren SC, Bronner-Fraser M (1999) Inhibition of sonic hedgehog signaling in vivo results in craniofacial neural crest cell death. Curr Biol 9: 1304–1314

    Article  PubMed  CAS  Google Scholar 

  • Aoyama H, Asamoto K (1988) Determination of somite cells: independence of cell differentiation and morphogenesis. Development 104: 15–28

    PubMed  CAS  Google Scholar 

  • Bitgood MJ, McMahon AP (1995) Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol 172: 126–138

    Article  PubMed  CAS  Google Scholar 

  • Bober E, Brand-Saberi B, Ebensperger C, Wilting J, Balling R, Paterson BM, Arnold HH, Christ B (1994) Initial steps of myogenesis in somites are independent of influence from axial structures. Development 120: 3073–3082

    PubMed  CAS  Google Scholar 

  • Borman WH,Yorde DE (1994) Barrier inhibition of a temporal neuraxial influence on early chick somitic myogenesis. Dev Dyn 200: 68–78

    Article  Google Scholar 

  • Borycki AG, Strunk KE, Savary R, Emerson CP Jr (1997) Distinct signal/response mechanisms regulate paxl and QmyoD activation in sclerotomal and myotomal lineages of quail somites. Dev Biol 185: 185–200

    Article  PubMed  CAS  Google Scholar 

  • Borycki AG, Mendham L, Emerson CP Jr (1998) Control of somite patterning by Sonic hedgehog and its downstream signal response genes. Development 125: 777–790

    PubMed  CAS  Google Scholar 

  • Borycki A, Brown AM, Emerson CP Jr (2000) Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. Development 127: 2075–2087

    PubMed  CAS  Google Scholar 

  • Brand-Saberi B, Christ B (2000) Evolution and development of distinct cell lineages derived from somites. Curr Top Dev Biol 48: 1–42

    Article  PubMed  CAS  Google Scholar 

  • Brand-Saberi B, Ebensperger C, Wilting J, Balling R, Christ B (1993) The ventralizing effect of the notochord on somite differentiation in chick embryos. Anat Embryol (Berl) 188: 239–245

    Article  CAS  Google Scholar 

  • Brand-Saberi B, Wilting J, Ebensperger C, Christ B (1996) The formation of somite compartments in the avian embryo. Int J Dev Biol 40: 411–420

    PubMed  CAS  Google Scholar 

  • Brill G, Kahane N, Carmeli C, von Schack D, Barde YA, Kalcheim C (1995) Epithelial-mesenchymal conversion of dermatome progenitors requires neural tube-derived signals: characterization of the role of Neurotrophin-3 Development 121: 2583–2594

    CAS  Google Scholar 

  • Buffinger N, Stockdale FE (1994) Myogenic specification in somites: induction by axial structures. Development 120: 1443–1452

    PubMed  CAS  Google Scholar 

  • Capdevila J, Tabin C, Johnson RL (1998) Control of dorsoventral somite patterning by Wnt-1 and beta-catenin. Dev Biol 193: 182–194

    Article  PubMed  CAS  Google Scholar 

  • Chevallier A, Kieny M, Mauger A (1977) Limb-somite relationship: origin of the limb musculature. J Embryol Exp Morphol 41: 245–258

    PubMed  CAS  Google Scholar 

  • Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA (1996) Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407–413

    Article  PubMed  CAS  Google Scholar 

  • Choi J, Schultheiss T, Lu M, Wachtler F, Kuruc N, Franke WW, Bader D, Fischman DA, Holtzer H (1989) Cellular and molecular biology of muscle development. Alan R. Liss, pp 27–36

    Google Scholar 

  • Christ B, Ordahl CP (1995) Early stages of chick somite development. Anat Embryol (Berl) 191: 381–396

    Article  CAS  Google Scholar 

  • Christ B, Jacob HJ, Jacob M (1972) Experimentelle Untersuchungen zur Somitenentwicklung bein HQhnerembryo. Z Anat Entwicklungsges 138: 82–97

    Article  CAS  Google Scholar 

  • Christ B, Jacob HJ, Jacob M (1977) Experimental analysis of the origin of the wing musculature in avian embryos. Anat Embryol (Berl) 150: 171–186

    Article  CAS  Google Scholar 

  • Christ B, Brand-Saberi B, Grim M, Wilting J (1992) Local signalling in dermomyotomal cell type specification. Anat Embryol (Berl) 186: 505–510

    Article  CAS  Google Scholar 

  • Cinnamon Y, Kahane N, Kalcheim C (1999) Characterization of the early development of specific hypaxial muscles from the ventrolateral myotome. Development 126: 4305–4315

    PubMed  CAS  Google Scholar 

  • Cossu G, Kelly R, Di Donna S, Vivarelli E, Buckingham M (1995) Myoblast differentiation during mammalian somitogenesis is dependent upon a community effect. Proc Natl Acad Sci USA 92: 2254–2258

    Article  PubMed  CAS  Google Scholar 

  • Cossu G, Kelly R, Tajbakhsh S, Di Donna S, Vivarelli E, Buckingham M (1996) Activation of different myogenic pathways: myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm. Development 122: 429–437

    PubMed  CAS  Google Scholar 

  • Couly G, Le Douarin NM (1988) The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo. Development 103: 101–113

    PubMed  Google Scholar 

  • Delfini M, Hirsinger E, Pourquié O, Duprez D (2000) Delta 1-activated notch inhibits muscle differentiation without affecting Myf5 and Pax3 expression in chick limb myogenesis. Development 127: 5213–5224

    PubMed  CAS  Google Scholar 

  • Denetclaw WF Jr, Christ B, Ordahl CP (1997) Location and growth of epaxial myotome precursor cells. Development 124: 1601–1610

    PubMed  CAS  Google Scholar 

  • Denetclaw WF, Ordahl CP (2000) The growth of the dermomyotome and formation of early myotome lineages in thoracolumbar somites of chicken embryos. Development 127: 893–905

    PubMed  CAS  Google Scholar 

  • Denetclaw WF, Berdougo E, Venters SJ, Ordahl CP (2001) Morphogenetic cell movements in the middle region of the dermomyotome dorsomedial lip associated with patterning and growth of the primary epaxial myotome. Development 128: 1745–1755

    PubMed  CAS  Google Scholar 

  • Dietrich S (1999) Regulation of hypaxial muscle development. Cell Tissue Res 296:175–182 Dietrich S, Schubert FR, Lumsden A (1997) Control of dorsoventral pattern in the chick paraxial mesoderm. Development 124: 3895–3908

    Google Scholar 

  • Dietrich S, Schubert FR, Healy C, Sharpe PT, Lumsden A (1998) Specification of the hypaxial musculature. Development 125: 2235–2249

    PubMed  CAS  Google Scholar 

  • Dockter J, Ordahl CP (2000) Dorsoventral axis determination in the somite: a re-examination. Development 127: 2201–2206

    PubMed  CAS  Google Scholar 

  • Duband JL, Dufour S, Hatta K, Takeichi M, Edelman GM, Thiery JP (1987) Adhesion molecules during somitogenesis in the avian embryo. J Cell Biol 104: 1361–1374

    Article  PubMed  CAS  Google Scholar 

  • Dudley AT, Robertson EJ (1997) Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn 208: 349–362

    Article  PubMed  CAS  Google Scholar 

  • Duprez D, Fournier-Thibault C, Le Douarin N (1998) Sonic Hedgehog induces proliferation of committed skeletal muscle cells in the chick limb. Development 125: 495–505

    PubMed  CAS  Google Scholar 

  • Ebensperger C, Wilting J, Brand-Saberi B, Mizutani Y, Christ B, Balling R, Koseki H (1995) Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos. Anat Embryol (Berl) 191: 297–310

    Article  CAS  Google Scholar 

  • Eichmann A, Marcelle C, Breant C, Le Douarin NM (1993) Two molecules related to the VEGF receptor are expressed in early endothelial cells during avian embryonic development. Mech Dev 42: 33–48

    Article  PubMed  CAS  Google Scholar 

  • Ellison ML, Ambrose EJ, Easty GC (1969) Myogenesis in chick embryo somites in vitro. J Embryol Exp Morph 21: 341–346

    PubMed  CAS  Google Scholar 

  • Eloy-Trinquet S, Mathis L, Nicolas JF (2000) Retrospective tracing of the developmental lineage of the mouse myotome. Curr Top Dev Biol 47: 33–80

    Article  PubMed  CAS  Google Scholar 

  • Fan CM, Tessier-Lavigne M (1994) Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog. Cell 79: 11751186

    Google Scholar 

  • Fan CM, Porter JA, Chiang C, Chang DT, Beachy PA, Tessier-Lavigne M (1995) Long-range sclerotome induction by Sonic Hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81: 457–465

    Article  PubMed  CAS  Google Scholar 

  • Fan CM, Lee CS, Tessier-Lavigne M (1997) A role for WNT proteins in induction of dermomyotome. Dev Biol 191: 160–165

    Article  PubMed  CAS  Google Scholar 

  • Gallera J (1966) Mise en évidence du Fmk de l’ectoblaste dans la différenciation des somites chez les oiseaux (Evidence for the role of the ectoblast in the differentiation of somites in birds). Rev Suisse Zool 73: 492–503

    PubMed  CAS  Google Scholar 

  • Gardner CA, Barald KF (1992) Expression patterns of engrailed-like proteins in the chick embryo. Dev Dyn 193: 370–388

    Article  PubMed  CAS  Google Scholar 

  • George-Weinstein M, Gerhart J, Reed R, Flynn J, Callihan B, Mattiacci M, Miehle C, Foti G, Lash JW, Weintraub H (1996) Skeletal myogenesis: the preferred pathway of chick embryo epiblast cells in vitro. Dev Biol 173: 279–291

    Article  PubMed  CAS  Google Scholar 

  • George-Weinstein M, Gerhart J, Blitz J, Simak E, Knudsen KA (1997) N-cadherin promotes the commitment and differentiation of skeletal muscle precursor cells. Dev Biol 185: 14–24

    Article  PubMed  CAS  Google Scholar 

  • George-Weinstein M, Gerhart J, Mattiacci-Paessler M, Simak E, Blitz J, Reed R, Knudsen K (1998) The role of stably committed and uncommitted cells in establishing tissues of the somite. Ann NY Acad Sci 842: 16–27

    Article  PubMed  CAS  Google Scholar 

  • Godsave SF, Slack JM (1989) Clonal analysis of mesoderm induction in Xenopus laevis. Dev Biol 134: 486–490

    Article  PubMed  CAS  Google Scholar 

  • Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP (1996) Conservation of the Hedgehog/Patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 10: 301–312

    Article  PubMed  CAS  Google Scholar 

  • Gossler A, Hrabe de Angelis M (1998) Somitogenesis. Curr Top Dev Biol 38: 225–287

    CAS  Google Scholar 

  • Goulding MD, Chalepakis G, Deutsch U, Erselius JR, Gruss P (1991) Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J 10: 1135–1147

    PubMed  CAS  Google Scholar 

  • Goulding M, Lumsden A, Paquette AJ (1994) Regulation of Pax-3 expression in the dermomyotome and its role in muscle development. Development 120: 957–971

    PubMed  CAS  Google Scholar 

  • Grunz H, Tacke L (1989) Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ Dev 28: 211–217

    Article  PubMed  CAS  Google Scholar 

  • Gurdon JB (1988) A community effect in animal development. Nature 336: 772–774

    Article  PubMed  CAS  Google Scholar 

  • Halevy O, Monsonego E, Marcelle C, Hodik V, Mett A, Pines M (1994) A new avian fibroblast growth factor receptor in myogenic and chondrogenic cell differentiation. Exp Cell Res 212: 278–284

    Article  PubMed  CAS  Google Scholar 

  • Hall BK (1977) Chondrogenesis of the somitic mesoderm. Advan Anat Embryol Cell Biol 53: 3–47

    CAS  Google Scholar 

  • Hemmati-Brivanlou A, Melton DA (1992) A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359: 609–614

    Article  PubMed  CAS  Google Scholar 

  • Hemmati-Brivanlou A, Melton D (1997) Vertebrate neural induction. Annu Rev Neurosci 20: 43–60

    Article  PubMed  CAS  Google Scholar 

  • Hirsinger E, Duprez D, Jouve C, Malapert P, Cooke J, Pourquié 0 (1997) Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize BMP4 in avian somite patterning. Development 124: 4605–4614

    CAS  Google Scholar 

  • Hirsinger E, Jouve C, Dubrulle J, Pourquié 0 (2000) Somite formation and patterning. Int Rev Cytol 198: 1–65

    CAS  Google Scholar 

  • Hollyday M, McMahon JA, McMahon AP (1995) Wnt expression patterns in chick embryo nervous system. Mech Dev 52: 9–25

    Article  PubMed  CAS  Google Scholar 

  • Holtzer H, Holtzer S (1976) Lineages, quantal cell cycles, and cell diversification. In: Muller-Berat H (ed) Progress in differentiation research. North-Holland, Amsterdam

    Google Scholar 

  • Huang R, Christ B (2000) Origin of the epaxial and hypaxial myotome in avian embryos. Anat Embryol (Berl) 202: 369–374

    Article  CAS  Google Scholar 

  • Jacob M, Christ B, Jacob HJ (1978) On the migration of myogenic stem cells into the prospective wing region of chick embryos. A scanning and transmission electron microscope study. Anat Embryol (Berl) 153: 179–193

    Google Scholar 

  • Johnson RL, Laufer E, Riddle RD, Tabin C (1994) Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites. Cell 79: 1165–1173

    Article  PubMed  Google Scholar 

  • Kahane N, Cinnamon Y, Kalcheim C (1998) The cellular mechanism by which the dermomyotome contributes to the second wave of myotome development. Development 125: 4259–4271

    PubMed  CAS  Google Scholar 

  • Kahane N, Cinnamon Y, Bachelet I, Kalcheim C (2001) The third wave of myotome colonization by mitotically competent progenitors: regulating the balance between differentiation and proliferation during muscle development. Development 128: 2187–2198

    PubMed  CAS  Google Scholar 

  • Kastner S, Elias MC, Rivera AJ, Yablonka-Reuveni Z (2000) Gene expression patterns of the fibroblast growth factors and their receptors during myogenesis of rat satellite cells. J Histochem Cytochem 48: 1079–1096

    Article  PubMed  CAS  Google Scholar 

  • Kenny-Mobbs T, Thorogood P (1987) Autonomy of differentiation in avian branchial somites and the influence of adjacent tissues. Development 100: 449–462

    PubMed  CAS  Google Scholar 

  • Kiefer JC, Hauschka SD (2001) Myf-5 is transiently expressed in nonmuscle mesoderm and exhibits dynamic regional changes within the presegmented mesoderm and somites I-IV. Dev Biol 232: 77–90

    Article  PubMed  CAS  Google Scholar 

  • Kos L, Chiang C, Mahon KA (1998) Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-31 expression. Mech Dev 70: 25–34

    Article  PubMed  CAS  Google Scholar 

  • Kruger M, Mennerich D, Fees S, Schafer R, Mundlos S, Braun T (2001) Sonic hedgehog is a sur- vival factor for hypaxial muscles during mouse development. Development 128: 743–752

    PubMed  CAS  Google Scholar 

  • Kuratani S, Martin JF, Wawersik S, Lilly B, Eichele G, Olson EN (1994) The expression pattern of the chick homeobox gene gMHox suggests a role in patterning of the limbs and face and in compartmentalization of somites. Dev Biol 161: 357–369

    Article  PubMed  CAS  Google Scholar 

  • Langman J, Nelson GR (1968) A radioautographic study of the development of the somite in the chick embryo. J Embryol Exp Morphol 19: 217–226

    PubMed  CAS  Google Scholar 

  • Lassar AB, Münsterberg AE (1996) The role of positive and negative signals in somite patterning. Curr Opin Neurobiol 6: 57–63

    Article  PubMed  CAS  Google Scholar 

  • Lee CS, Buttitta LA, May NR, Kispert A, Fan CM (2000) SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm. Development 127: 109–118

    PubMed  CAS  Google Scholar 

  • Li L, Cserjesi P, Olson EN (1995) Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev Biol 172: 280–292

    Article  PubMed  CAS  Google Scholar 

  • Lyons KM, Hogan BL, Robertson EJ (1995) Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech Dev 50: 71–83

    Article  PubMed  CAS  Google Scholar 

  • Marcelle C, Eichmann A, Halevy O, Breant C, Le Douarin NM (1994) Distinct developmental expression of a new avian fibroblast growth factor receptor. Development 120: 683–694

    PubMed  CAS  Google Scholar 

  • Marcelle C, Wolf J, Bronner-Fraser M (1995) The in vivo expression of the FGF receptor FREK mRNA in avian myoblasts suggests a role in muscle growth and differentiation. Dev Biol 172: 100–114

    Article  PubMed  CAS  Google Scholar 

  • Marcelle C, Stark MR, Bronner-Fraser M (1997) Coordinate actions of BMPs, Wnts, Shh and noggin mediate patterning of the dorsal somite. Development 124: 3955–3963

    Google Scholar 

  • Marcelle C, Ahlgren S, Bronner-Fraser M (1999) In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog. Dev Biol 214: 277–287

    Article  PubMed  CAS  Google Scholar 

  • Maroto M, Pourquié 0 (2001) A molecular clock involved in somite segmentation. Curr Top Dev Biol 51: 221–248

    CAS  Google Scholar 

  • Maroto M, Reshef R, Münsterberg AE, Koester S, Goulding M, Lassar AB (1997) Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue. Cell 89: 139–148

    Article  PubMed  CAS  Google Scholar 

  • McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP (1998) Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev 12: 1438–1452

    Article  PubMed  CAS  Google Scholar 

  • Muller TS, Ebensperger C, Neubuser A, Koseki H, Balling R, Christ B, Wilting J (1996) Expression of avian Paxl and Pax9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm. Dev Biol 178: 403417

    Google Scholar 

  • Münsterberg AE, Lassar AB (1995) Combinatorial signals from the neural tube, floor plate and notochord induce myogenic bHLH gene expression in the somite. Development 121: 651–660

    PubMed  Google Scholar 

  • Münsterberg AE, Kitajewski J, Bumcrot DA, McMahon AP, Lassar AB (1995) Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev 9: 2911–2922

    Article  PubMed  Google Scholar 

  • Murtaugh LC, Chyung JH, Lassar AB (1999) Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. Genes Dev 13: 225–237

    Article  PubMed  CAS  Google Scholar 

  • Nicolas JF, Mathis L, Bonnerot C, Saurin W (1996) Evidence in the mouse for self-renewing stem cells in the formation of a segmented longitudinal structure, the myotome. Development 122: 2933–2946

    PubMed  CAS  Google Scholar 

  • Nicolet G (1971) Avian gastrulation. Advan Morphogen 9: 231–262

    CAS  Google Scholar 

  • Nishita M, Hashimoto MK, Ogata S, Laurent MN, Ueno N, Shibuya H, Cho KW (2000) Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann’s organizer. Nature 403: 781–785

    Article  PubMed  CAS  Google Scholar 

  • Noden DM (1990) Origins and assembly of avian embryonic blood vessels. Ann NY Acad Sci 588: 236–249

    Article  PubMed  CAS  Google Scholar 

  • O’Hare JM (1972) Differentiation of chick embryo somites in chorioallantoic culture. J Embryol Exp Morph 27: 215–228

    PubMed  Google Scholar 

  • Olivera-Martinez I, Coltey M, Dhouailly D, Pourquié 0 (2000) Mediolateral somitic origin of ribs and dermis determined by quail-chick chimeras. Development 127: 4611–4617

    CAS  Google Scholar 

  • Ooi VE, Sanders EJ, Bellairs R (1986) The contribution of the primitive streak to the somites in the avian embryo. J Embryol Exp Morphol 92: 193–206

    PubMed  CAS  Google Scholar 

  • Ordahl CP (2000) Somitogenesis (parts 1 and 2) In: Current topics in developmental biology, vol 47. Academic Press, London

    Google Scholar 

  • Ordahl CP, Le Douarin NM (1992) Two myogenic lineages within the developing somite. Development 114: 339–353

    PubMed  CAS  Google Scholar 

  • Ordahl CP, Berdougo E, Venters SJ, Denetclaw WF (2001) The dermomyotome dorsomedial lip drives growth and morphogenesis of both the primary myotome and dermomyotome epithelium. Development 128: 1731–1744

    PubMed  CAS  Google Scholar 

  • Ott MO, Bober E, Lyons G, Arnold H, Buckingham M (1991) Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo. Development 111: 1097–1107

    PubMed  CAS  Google Scholar 

  • Parr BA, McMahon AP (1994) Wnt genes and vertebrate development. Curr Opin Genet Dev 4: 523–528

    Article  PubMed  CAS  Google Scholar 

  • Parr BA, Shea MJ, Vassileva G, McMahon AP (1993) Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119: 247–261

    PubMed  CAS  Google Scholar 

  • Pourquié O, Coltey M, Teillet MA, Ordahl C, Le Douarin NM (1993) Control of dorsoventral patterning of somitic derivatives by notochord and floor plate. Proc Natl Acad Sci USA 90: 5242–5246

    Article  PubMed  Google Scholar 

  • Pourquié O, Fan CM, Coltey M, Hirsinger E, Watanabe Y, Breant C, Francis-West P, Brickell P, Tessier-Lavigne M, Le Douarin NM (1996) Lateral and axial signals involved in avian somite patterning: a role for BMP4 Cell 84: 461–471

    Google Scholar 

  • Pownall ME, Emerson CP Jr (1992) Sequential activation of three myogenic regulatory genes during somite morphogenesis in quail embryos. Dev Biol 151: 67–79

    Article  PubMed  CAS  Google Scholar 

  • Pownall ME, Strunk KE, Emerson CP Jr (1996) Notochord signals control the transcriptional cascade of myogenic bHLH genes in somites of quail embryos. Development 122: 1475–1488

    PubMed  CAS  Google Scholar 

  • Psychoyos D, Stern CD (1996) Fates and migratory routes of primitive streak cells in the chickembryo. Development 122: 1523–1534

    PubMed  CAS  Google Scholar 

  • Reshef R, Maroto M, Lassar AB (1998) Regulation of dorsal somitic cell fates: BMPs and Noggincontrol the timing and pattern of myogenic regulator expression. Gene Dev 12: 290–303

    Google Scholar 

  • Richardson MK, Allen SP, Wright GM, Raynaud A, Hanken J (1998) Somite number and vertebrate evolution. Development 125: 151–160

    PubMed  CAS  Google Scholar 

  • Roelink H, Porter JA, Chiang C, Tanabe Y, Chang DT, Beachy PA, Jessell TM (1995) Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 81: 445–455

    Article  PubMed  CAS  Google Scholar 

  • Rong PM, Teillet MA, Ziller C, Le Douarin NM (1992) The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation. Development 115: 657–672

    PubMed  CAS  Google Scholar 

  • Sasaki H, Hui C, Nakafuku M, Kondoh H (1997) A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 124: 1313–1322

    PubMed  CAS  Google Scholar 

  • Sato SM, Sargent TD (1989) Development of neural inducing capacity in dissociated Xenopus embryos. Dev Biol 134: 263–266

    Article  PubMed  CAS  Google Scholar 

  • Scaal M, Fuchtbauer EM, Brand-Saberi B (2001) cDermo-1 expression indicates a role in avian skin development. Anat Embryol (Berl) 203: 1–7

    Google Scholar 

  • Schoenwolf GC, Garcia-Martinez V, Dias MS (1992) Mesoderm movement and fate during avian gastrulation and neurulation. Dev Dyn 193: 235–248

    Article  PubMed  CAS  Google Scholar 

  • Selleck MA, Stern CD (1991) Fate mapping and cell lineage analysis of Hensen’s node in the chick embryo. Development 112: 615–626

    PubMed  CAS  Google Scholar 

  • Solloway MJ, Robertson EJ (1999) Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126: 1753–1768

    PubMed  CAS  Google Scholar 

  • Solursh M, Drake C, Meier S (1987) The migration of myogenic cells from the somites at the wing level in avian embryos. Dev Biol 121: 389–396

    Article  PubMed  CAS  Google Scholar 

  • Sosic D, Brand-Saberi B, Schmidt C, Christ B, Olson EN (1997) Regulation of paraxis expression and somite formation by ectoderm-and neural tube-derived signals. Dev Biol 185: 229–243

    Article  PubMed  CAS  Google Scholar 

  • Spence MS, Yip J, Erickson CA (1996) The dorsal neural tube organizes the dermamyotome and induces axial myocytes in the avian embryo. Development 122: 231–241

    PubMed  CAS  Google Scholar 

  • Spratt NT (1955) Analysis of the organizer center in the early chick embryo. I. Localisation of the prospective notochord and somite cells. J Exp Zool 128: 121–162

    Article  Google Scholar 

  • Stern CD, Bellairs R (1984) Mitotic activity during somite segmentation in the early chick embryo. Anat Embryol 169: 97–102

    Article  PubMed  CAS  Google Scholar 

  • Stern HM, Hauschka SD (1995) Neural tube and notochord promote in vitro myogenesis in single somite explants. Dev Biol 167: 87–103

    Article  PubMed  CAS  Google Scholar 

  • Stern HM, Brown AM, Hauschka SD (1995) Myogenesis in paraxial mesoderm: preferential induction by dorsal neural tube and by cells expressing Wnt-1 Development 121: 3675–3686

    CAS  Google Scholar 

  • Stockdale FE, Nikovits W Jr, Christ B (2000) Molecular and cellular biology of avian somite development. Dev Dyn 219: 304–321

    Article  PubMed  CAS  Google Scholar 

  • Stone DM, Hynes M, Armanini M, Swanson TA, Gu Q, Johnson RL, Scott MP, Pennica D, Goddard A, Phillips H et al. (1996) The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384: 129–134

    Article  PubMed  CAS  Google Scholar 

  • Tabata T, Kornberg TB (1994) Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76: 89–102

    Article  PubMed  CAS  Google Scholar 

  • Tajbakhsh S, Buckingham M (2000) The birth of muscle progenitor cells in the mouse: spatiotemporal considerations. Curr Top Dev Biol 48: 225–268

    Article  PubMed  CAS  Google Scholar 

  • Tajbakhsh S, Borello U, Vivarelli E, Kelly R, Papkoff J, Duprez D, Buckingham M, Cossu G (1998) Differential activation of Myf5 and MyoD by different Wnts in explants of mouse paraxial mesoderm and the later activation of myogenesis in the absence of Myf5 Development 125: 4155–4162

    CAS  Google Scholar 

  • Teillet MA, Le Douarin NM (1983) Consequences of neural tube and notochord excision on the development of the peripheral nervous system in the chick embryo. Dev Biol 98: 192–211

    Article  PubMed  CAS  Google Scholar 

  • Teillet M, Watanabe Y, Jeffs P, Duprez D, Lapointe F, Le Douarin NM (1998) Sonic hedgehog is required for survival of both myogenic and chondrogenic somitic lineages. Development 125: 2019–2030

    PubMed  CAS  Google Scholar 

  • Valinsky JE, Le Douarin NM (1985) Production of plasminogen activator by migrating cephalic neural crest cells. EMBO J 4: 1403–1406

    PubMed  CAS  Google Scholar 

  • Veini M, Bellairs R (1991) Early mesoderm differentiation in the chick embryo. Anat Embryol 183: 143–149

    Article  PubMed  CAS  Google Scholar 

  • Vivarelli E, Cossu G (1986) Neural control of early myogenic differentiation in cultures of mouse somites. Dev Biol 117: 319–325

    Article  PubMed  CAS  Google Scholar 

  • Wachtler F, Christ B (1992) The basic embryology of skeletal muscle formation in vertebrates: the avian model. Semin Dev Biol 3: 217–227

    Google Scholar 

  • Wachtler F, Christ B, Jacob HJ (1982) Grafting experiments on determination and migratory behaviour of presomitic, somitic and somatopleural cells in avian embryos. Anat Embryol 164: 369–378

    Article  PubMed  CAS  Google Scholar 

  • Wagner J, Schmidt C, Nikowits W Jr, Christ B (2000) Compartmentalization of the somite and myogenesis in chick embryos are influenced by wnt expression. Dev Biol 228: 86–94

    Article  PubMed  CAS  Google Scholar 

  • Watterson R, Fowler I, Fowler BJ (1954) The role of the neural tube and notochord in the development of the axial skeleton of the chick. Am J Anat 95: 337–399

    Article  PubMed  CAS  Google Scholar 

  • Williams LW (1910) The somites of the chick. Am J Anat 11: 55–100

    Article  Google Scholar 

  • Williams BA, Ordahl CP (1994) Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification. Development 120: 785–796

    PubMed  CAS  Google Scholar 

  • Williams BA, Ordahl CP (1997) Emergence of determined myotome precursor cells in the somite. Development 124: 4983–4997

    PubMed  CAS  Google Scholar 

  • Wilson V, Beddington RS (1996) Cell fate and morphogenetic movement in the late mouse primitive streak. Mech Dev 55: 79–89

    Article  PubMed  CAS  Google Scholar 

  • Wilting J, Brand-Saberi B, Huang R, Zhi Q, Kontges G, Ordahl CP, Christ B (1995) Angiogenic potential of the avian somite. Dev Dyn 202: 165–171

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Developmental Biology Institute of Marseille, Campus de Luminy, University Aix-Marseille II, LGPD, CNRS UMR 6545, Case 907, 13288, Marseille cedex, France

    Claudia Linker

Authors
  1. Christophe Marcelle
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Cynthia Lesbros
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Claudia Linker
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute of Anatomy II, Albert Ludwigs University Freiburg, Albertstraße 17, 79104, Freiburg, Germany

    Beate Brand-Saberi

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Marcelle, C., Lesbros, C., Linker, C. (2002). Somite Patterning: a Few More Pieces of the Puzzle. In: Brand-Saberi, B. (eds) Vertebrate Myogenesis. Results and Problems in Cell Differentiation, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-45686-5_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-45686-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-07735-7

  • Online ISBN: 978-3-540-45686-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation