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Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials pp 373–392Cite as

TEM Study of Bone and Scaffold Materials

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Abstract

This chapter summarizes the application of transmission electron microscopy (TEM) to study the structure of normal and pathological bone, the interface between bone and scaffold materials, and the nucleation and structure of calcium phosphate on various scaffold materials. The principles of different TEM techniques, including bright-field image, dark-field image, electron diffraction, and high-resolution TEM are also briefly reviewed. The protocol of biological tissue processing for TEM is introduced. The typical TEM applications in investigation of bone and scaffold materials are high-lighted as reference for related study and application.

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Author information

Authors and Affiliations

  1. Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Material Science and Engineering, Southwest Jiaotong University, Chengdu, China

    Shu-Xin Qu & Xiong Lu

  2. Department of Mechanical Engineering, Hong Kong University of Science and Technology, Hong Kong, China

    Xiong Lu & Yang Leng

Authors
  1. Shu-Xin Qu
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  2. Xiong Lu
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  3. Yang Leng
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Corresponding author

Correspondence to Shu-Xin Qu .

Editor information

Editors and Affiliations

  1. Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China

    Ling Qin (Professor) & Kwok Sui Leung (Professor of Department of Orthopaedics & Traumatology) (Professor) &  (Professor of Department of Orthopaedics & Traumatology)

  2. University of California, San Francisco

    Harry K. Genant (Professor Emeritus, Chairman Emeritus and Board of Directors) (Professor Emeritus, Chairman Emeritus and Board of Directors)

  3. Synarc, Inc, USA

    Harry K. Genant (Professor Emeritus, Chairman Emeritus and Board of Directors) (Professor Emeritus, Chairman Emeritus and Board of Directors)

  4. Department of Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong SAR, China

    James F. Griffith

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© 2007 Springer-Verlag Berlin Heidelberg

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Qu, SX., Lu, X., Leng, Y. (2007). TEM Study of Bone and Scaffold Materials. In: Qin, L., Genant, H.K., Griffith, J.F., Leung, K.S. (eds) Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-45456-4_22

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  • DOI: https://doi.org/10.1007/978-3-540-45456-4_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-45454-0

  • Online ISBN: 978-3-540-45456-4

  • eBook Packages: MedicineMedicine (R0)

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