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Characteristics of Biological Networks

  • Albert-László Barabási
  • Zoltán N. Oltvai
  • Stefan Wuchty
Part IV Biological Networks
Part of the Lecture Notes in Physics book series (LNP, volume 650)

Abstract

Network principles describe uniformly systems as diverse as the cell or the Internet. The emergence of these networks is driven by self-organizing processes that are governed by simple but generic laws. While unraveling the complex and interwoven systems of different interacting units, it has become clear that the topology of networks of different origin share the same characteristics on the large scale. In biological systems, networks appear in many different disguises ranging from protein interactions to metabolic networks. In this paper, we survey the most prominent characteristics of biological networks focusing on the emergence of scale-free architecture and hierarchical arrangement of functional modules. Finally, we present empirical evidence that cohesive parts of the protein interaction network have a significantly higher tendency to be evolutionary conserved.

Keywords

Metabolic Network Random Graph Degree Distribution Random Network Biological Network 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Authors and Affiliations

  • Albert-László Barabási
    • 1
  • Zoltán N. Oltvai
    • 2
  • Stefan Wuchty
    • 1
  1. 1.Department of Physics, University of Notre Dame, Notre Dame, IN 46556USA
  2. 2.Department of Pathology, Northwestern University, Chicago, IL 60611USA

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