Multigrain Crystallography

Abstract

Traditionally, x-ray crystallography is based on either powder diffraction data or single-crystal studies. Both methods have their distinct advantages. Single-crystal data are indispensable for structural refinement of large molecules, in particular proteins, and for high-accuracy work such as the generation of charge density maps. Powder diffraction, on the other hand, is required for in situ dynamic studies and for use whenever suitable single crystals are not available. This includes most applied studies. ...