Abstract
In radiation therapy, patient positioning uncertainty and organ motion require that a volume larger than the actual tumour (named the planning target volume [PTV]) be irradiated to ensure that the tumour receives the prescribed dose. Image-guided patient positioning can correct targeting errors, thus reducing the uncertainty in the position of the tumour, and therefore, the size of the PTV. Positioning uncertainties are reduced with frequent imaging, but require increasing the overall time of a treatment session. We compare conventional ‘off-line’ error correction protocols to our ‘on-line’ correction protocol for prostate cancer patients. Simulations indicate that our on-line protocol leads to much smaller residual uncertainty than off-line protocols, leading to much smaller PTV margins. Our on-line protocol allows the irradiation of substantially smaller volumes than conventional off-line protocols, leading to reduced normal tissue complications. Introducing an “intervention threshold” has retained some of the efficiency of the off-line strategy.
Chapter PDF
Similar content being viewed by others
Keywords
- Planning Target Volume
- Dose Distribution
- Clinical Target Volume
- Portal Imaging
- Electronic Portal Imaging Device
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
International Commission on Radiation Units, and Measurements. ICRU Report 50: Prescribing, recording, and reporting photon beam therapy. Bethesda, MD: International Commission on Radiation Units and Measurements (1993)
Herman, M.G., Balter, J.M., Jaffray, D.A., McGee, K.P., Munro, P., Shalev, S., van Herk, M., Wong, J.W.: Clinical use of electronic portal imaging: report of AAPM Radiation Therapy Committee Task Group 58. Medical Physics 28, 712–737 (2001)
Wu, J., Haycocks, T., Alasti, H., Ottewell, G., Middlemiss, N., Abdolell, M., Warde, P., Toi, A., Catton, C.: Positioning errors and prostate motion during conformal prostate radiotherapy using on-line isocentre set-up verification and implanted prostate markers. Radiotherapy and Oncology 61, 127–133 (2001)
Bel, A., van Herk, M., Bartelink, H., et al.: A verification procedure to improve patient setup accuracy using portal images. Radiotherapy and Oncology 29, 253–260 (1993)
de Boer, H.C.J., Heijmen, B.J.M.: A protocol for the reduction of systematic patient setup errors with minimal portal imaging workload. International Journal of Radiation Oncology Biology Physics 50, 1350–1365 (2001)
van Herk, M., Bruce, A., Kroes, A.P.G., Shouman, T., Touw, A., Lebesque, J.V.: Quantification of organ motion during conformal radiotherapy of the prostate by three dimensional image registration. International Journal of Radiation Oncology Biology Physics 33, 1311–1320 (1995)
Bel, A., Vos, P.H., Rodrigus, P.T.R., Creutzberg, C.L., Visser, A.G., Stroom, J.C., Lebesque, J.V.: High-precision prostate cancer irradiation by clinical application of an offline setup verification procedure using portal imaging. International Journal of Radiation Oncology Biology Physics 35, 321–332 (1996)
van Herk, M., Remeijer, P., Lebesque, J.V.: Inclusion of geometric uncertainties in treatment plan evaluation. International Journal of Radiation Oncology Biology Physics 52, 1407–1422 (2002)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Craig, T., Sharpe, M., Haycocks, T., Bissionnette, JP., Catton, C., Jaffray, D. (2003). Comparison of Correction Protocols for Image-Guided Radiation Therapy. In: Ellis, R.E., Peters, T.M. (eds) Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003. MICCAI 2003. Lecture Notes in Computer Science, vol 2879. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-39903-2_33
Download citation
DOI: https://doi.org/10.1007/978-3-540-39903-2_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-20464-0
Online ISBN: 978-3-540-39903-2
eBook Packages: Springer Book Archive